Q8RR32 (PPNK2_THEEB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2
Short name=Poly(P)/ATP NAD kinase 2
EC=2.7.1.23

Gene names

Name:	ppnK2
Ordered Locus Names:	tlr0484

Organism

Thermosynechococcus elongatus (strain BP-1)

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361		PRO_0000120677

Sequences

	Sequence		Length	Mass (Da)
	Q8RR32 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: AEF9B16BCCAA9FA7	FASTA	306	33,683
	10 20 30 40 50 60 MQLNQVIVVH KAGDRQSKEW ADRASRQLQQ RGANVLVGPS GPKDNPYPVF MASVTEPIDL 70 80 90 100 110 120 AVVLGGDGTS LAAARHLAAA GVPILAVNVG GHLGFLTEPL ELFRDMEAVW DRLERDEYAM 130 140 150 160 170 180 QQRMMLQAQV FEGSKAHPEA VGDRYYALNE MCIKPASADR MITAILEMEI DGDVVDQYQG 190 200 210 220 230 240 DGLLVATPTG STCYTVAANG PILHPGMEAL VVTPICPLSL SSRPIVLPAR SSVSIWPLED 250 260 270 280 290 300 HSLNTKLWMD GVLATSIWPG QRVQVTMADC QARFIILRDH YSFYQTLREK LAWAGARIPY HNNHRN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Circadian clock gene cluster kaiABC in Synechococcus elongatus." Uzumaki T., Hayashi F., Onai K., Ishiura M. Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB071375 Genomic DNA. Translation: BAB85986.1. BA000039 Genomic DNA. Translation: BAC08036.1.
RefSeq	NP_681274.1. NC_004113.1.
3D structure databases
ProteinModelPortal	Q8RR32.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8RR32.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1012214.
GenomeReviews	Gene locus tlr0484 in contig BA000039_GR.
KEGG	tel:tlr0484.
NMPDR	fig|197221.1.peg.483.
PATRIC	23926212. VBITheElo119873_0509.
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	TGSTCYT.
ProtClustDB	PRK02645.
Enzyme and pathway databases
BioCyc	TELO197221:TLR0484-MONOMER.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPNK2_THEEB

Accession

Primary (citable) accession number: Q8RR32

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 22, 2003
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program