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Q8RR32 (PPNK2_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2

Short name=Poly(P)/ATP NAD kinase 2
EC=2.7.1.23
Gene names
Name:ppnK2
Ordered Locus Names:tlr0484
OrganismThermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP-Rule MF_00361
PRO_0000120677

Sequences

Sequence LengthMass (Da)Tools
Q8RR32 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: AEF9B16BCCAA9FA7

FASTA30633,683
        10         20         30         40         50         60 
MQLNQVIVVH KAGDRQSKEW ADRASRQLQQ RGANVLVGPS GPKDNPYPVF MASVTEPIDL 

        70         80         90        100        110        120 
AVVLGGDGTS LAAARHLAAA GVPILAVNVG GHLGFLTEPL ELFRDMEAVW DRLERDEYAM 

       130        140        150        160        170        180 
QQRMMLQAQV FEGSKAHPEA VGDRYYALNE MCIKPASADR MITAILEMEI DGDVVDQYQG 

       190        200        210        220        230        240 
DGLLVATPTG STCYTVAANG PILHPGMEAL VVTPICPLSL SSRPIVLPAR SSVSIWPLED 

       250        260        270        280        290        300 
HSLNTKLWMD GVLATSIWPG QRVQVTMADC QARFIILRDH YSFYQTLREK LAWAGARIPY 


HNNHRN 

« Hide

References

« Hide 'large scale' references
[1]"Circadian clock gene cluster kaiABC in Synechococcus elongatus."
Uzumaki T., Hayashi F., Onai K., Ishiura M.
Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB071375 Genomic DNA. Translation: BAB85986.1.
BA000039 Genomic DNA. Translation: BAC08036.1.
RefSeqNP_681274.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8RR32.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING197221.tlr0484.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC08036; BAC08036; BAC08036.
GeneID1012214.
KEGGtel:tlr0484.
PATRIC23926212. VBITheElo119873_0509.

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000227222.
KOK00858.
OMAKLHWAGS.
OrthoDBEOG6PZXDR.
ProtClustDBPRK02645.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK2_THEEB
AccessionPrimary (citable) accession number: Q8RR32
Entry history
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: June 1, 2002
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families