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Protein

Putative thymidine phosphorylase

Gene
N/A
Organism
Legionella pneumophila
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
OrganismiLegionella pneumophila
Taxonomic identifieri446 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000590951 – 517Putative thymidine phosphorylaseAdd BLAST517

Structurei

3D structure databases

ProteinModelPortaliQ8RNP4
SMRiQ8RNP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA

Family and domain databases

Gene3Di3.40.1030.10, 2 hits
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8RNP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHDSFLSANG GFVVSKKTPH GLRLKHLGIK TYHEAIIYMR EDCHVCHSEG
60 70 80 90 100
FEVQTRIQVT LGSRSIIATL NVVTSELLQP GEAGLSDYAW ESLHAKEGDE
110 120 130 140 150
IQVSHPKPLE SLSYVHAKIY GNELSFEQMK VIIDDVLSGR LSDVQISAFL
160 170 180 190 200
AASGAGRLTR TEVMKLTKAM IDSGDRLSWP SPLVVDKHCV GGLPGNRTTL
210 220 230 240 250
IVVPIVASFG LMIPKTSSRA ITSPAGTADT METLAPVHLS PQKMRQVVEQ
260 270 280 290 300
ENGCIVWGGA VSLSPADDVL IRVERAIDLD SEGQLVASIL SKKIATGATH
310 320 330 340 350
AVIDIPVGPT AKVRNQSMAL LLKQSLEEVG NELGLVVRAL FTDGSQPVGH
360 370 380 390 400
GIGPSLEARD VLAVLQGLPD APNDLRERAL TLAGAALECS SKVPPGLGKS
410 420 430 440 450
IATQLLESGQ AFKKFQAICE AQGGMRELTK ARFTYPVVAA KEGKVSLIDN
460 470 480 490 500
RKLAKIAKLA GAPKSKSAGI DLHAHVGESV EQGEPLFTIH SESLGELHYA
510
CDLLRDKQDI IILGENP
Length:517
Mass (Da):55,296
Last modified:June 1, 2002 - v1
Checksum:i3903064A69DFB546
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF480912 Genomic DNA Translation: AAM00626.1
RefSeqiWP_010946757.1, NZ_PQWZ01000008.1

Similar proteinsi

Entry informationi

Entry nameiTYPH_LEGPN
AccessioniPrimary (citable) accession number: Q8RNP4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health