Reviewed, UniProtKB/Swiss-Prot Q8RKI9 (TARI_BACSU)

Names and origin

Protein names

Recommended name:
    Putative ribitol-5-phosphate cytidylyltransferase
    EC=2.7.7.40

Gene names

Name:

tarI

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	237 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides activated ribitol phosphate for teichoic acid synthesis Potential.
Catalytic activity	CTP + D-ribitol 5-phosphate = diphosphate + CDP-ribitol. HAMAP MF_00108
Pathway	Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis. HAMAP MF_00108
Sequence similarities	Belongs to the ispD family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation Teichoic acid biosynthesis
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW teichoic acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW terpenoid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity Inferred from electronic annotation. Source: HAMAP D-ribitol-5-phosphate cytidylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 237	237	Putative ribitol-5-phosphate cytidylyltransferase HAMAP MF_00108		PRO_0000075685

Sequences

	Sequence		Length	Mass (Da)
	Q8RKI9-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 0B03F2F41D6CE5AB	FASTA	237	26,848
	10 20 30 40 50 60 MIYAEILAGG KGSRMGNVNM PKQFLPLNKR PIIIHTVEKF LLNDRFDKIL IVSPKEWINH 70 80 90 100 110 120 TKDILKKFIG QDDRLVVVEG GSDRNESIMS GIRYIEKEFG IQDNDVIITH DSVRPFLTHR 130 140 150 160 170 180 IIDENIDAVL QYGAVDTVIS AIDTIIASED QEFISDIPVR DNMYQGQTPQ SFRISKLVEL 190 200 210 220 230 YNKLSDEQKA VLTDACKICS LAGEKVKLVR GEVFNIKVTT PYDLKVANAI LQERISQ

References

[1]

"Comparison of ribitol and glycerol teichoic acid genes in Bacillus subtilis W23 and 168: identical function, similar divergent organization, but different regulation." Lazarevic V., Abellan F.-X., Beggah Moeller S., Karamata D., Maueel C. Microbiology 148:815-824(2002) [PubMed: 11882717] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PUTATIVE FUNCTION. Strain: W23.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ313428 Genomic DNA. Translation: CAC86109.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.7.40. 150.
Family and domain databases
HAMAP	MF_00108. Divergent sequence. [Tree]
InterPro	IPR001228. ISPD_synthase. IPR018294. ISPD_synthase_CS. [Graphical view]
Pfam	PF01128. IspD. 1 hit. [Graphical view]
PROSITE	PS01295. ISPD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TARI_BACSU

Accession

Primary (citable) accession number: Q8RKI9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	June 1, 2002
Last modified:	May 5, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)