Reviewed, UniProtKB/Swiss-Prot Q8RKI7 (TARA_BACSU)

Names and origin

Protein names

Recommended name:
    Putative N-acetylmannosaminyltransferase
    EC=2.4.1.187
Alternative name(s):
    UDP-N-acetylmannosamine transferase
    N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase

Gene names

Name:

tarA

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid Potential.
Catalytic activity	UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol = UDP + N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.
Pathway	Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
Subcellular location	Secreted › cell wall By similarity.
Sequence similarities	Belongs to the glycosyltransferase 26 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation Teichoic acid biosynthesis
Cellular component	Secreted
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW teichoic acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	Putative N-acetylmannosaminyltransferase		PRO_0000208439

Sequences

	Sequence		Length	Mass (Da)
	Q8RKI7-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: C10CE10C0337A56F	FASTA	257	29,140
	10 20 30 40 50 60 MQTKPINQLD FVDSELTSFV SHLETTYLDQ NKGAFIVTAN PEIGFEAMQN PRYEAVLSSA 70 80 90 100 110 120 DFILPDGIGV VMVSKLIGKP LQSRIAGYDL FTSLLDKADQ KKKRVFFYGA AKHVIAETIE 130 140 150 160 170 180 RVKRDFPGIE IAGYSDGYVK DQREVADKIA ASTPDMVFVA LGYPNQEFFI HKYRHLFPQA 190 200 210 220 230 240 VAVGLGGSFD VFSGNVKRAP SFFIRFHLEW MYRLLTNPAR WRRMLSIPKY VTAVLKHERA 250 SAKPHYTGQV KDQSRHL

References

[1]

"Comparison of ribitol and glycerol teichoic acid genes in Bacillus subtilis W23 and 168: identical function, similar divergent organization, but different regulation." Lazarevic V., Abellan F.-X., Beggah Moeller S., Karamata D., Maueel C. Microbiology 148:815-824(2002) [PubMed: 11882717] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PUTATIVE FUNCTION. Strain: W23.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ313428 Genomic DNA. Translation: CAC86111.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT26. Glycosyltransferase Family 26.
Enzyme and pathway databases
BRENDA	2.4.1.187. 150.
Family and domain databases
InterPro	IPR004629. WecB_TagA_CpsF. [Graphical view]
Pfam	PF03808. Glyco_tran_WecB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00696. wecB_tagA_cpsF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TARA_BACSU

Accession

Primary (citable) accession number: Q8RKI7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2003
Last sequence update:	June 1, 2002
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)