Q8RKI7 (TARA_BACPZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative N-acetylmannosaminyltransferase
EC=2.4.1.187

Alternative name(s):
N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase
UDP-N-acetylmannosamine transferase

Gene names

Name:	tarA
Ordered Locus Names:	BSUW23_17555

Organism

Bacillus subtilis subsp. spizizenii (strain ATCC 23059 / NRRL B-14472 / W23) [Complete proteome] [HAMAP]

Taxonomic identifier

655816 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid Potential. Ref.1
Catalytic activity	UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol = UDP + N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.
Pathway	Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
Subcellular location	Secreted › cell wall By similarity.
Sequence similarities	Belongs to the glycosyltransferase 26 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation Teichoic acid biosynthesis
Cellular component	Secreted
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW teichoic acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	Putative N-acetylmannosaminyltransferase		PRO_0000208439

Sequences

	Sequence		Length	Mass (Da)
	Q8RKI7 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: C10CE10C0337A56F	FASTA	257	29,140
	10 20 30 40 50 60 MQTKPINQLD FVDSELTSFV SHLETTYLDQ NKGAFIVTAN PEIGFEAMQN PRYEAVLSSA 70 80 90 100 110 120 DFILPDGIGV VMVSKLIGKP LQSRIAGYDL FTSLLDKADQ KKKRVFFYGA AKHVIAETIE 130 140 150 160 170 180 RVKRDFPGIE IAGYSDGYVK DQREVADKIA ASTPDMVFVA LGYPNQEFFI HKYRHLFPQA 190 200 210 220 230 240 VAVGLGGSFD VFSGNVKRAP SFFIRFHLEW MYRLLTNPAR WRRMLSIPKY VTAVLKHERA 250 SAKPHYTGQV KDQSRHL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparison of ribitol and glycerol teichoic acid genes in Bacillus subtilis W23 and 168: identical function, similar divergent organization, but different regulation." Lazarevic V., Abellan F.-X., Beggah Moeller S., Karamata D., Maueel C. Microbiology 148:815-824(2002) [PubMed: 11882717] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PUTATIVE FUNCTION. Strain: ATCC 23059 / NRRL B-14472 / W23.
[2]	"Minor teichoic acid of Bacillus subtilis W23." Soldo B., Freymond P.P., Karamata D., Lazarevic V. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 23059 / NRRL B-14472 / W23.
[3]	"Complete genome sequence of Bacillus subtilis subsp. spizizenii str. W23." Zeigler D.R. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23059 / NRRL B-14472 / W23.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ313428 Genomic DNA. Translation: CAC86111.1. AM260209 Genomic DNA. Translation: CAJ97398.1. CP002183 Genomic DNA. Translation: ADM39546.1.
RefSeq	YP_003867855.1. NC_014479.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT26. Glycosyltransferase Family 26.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9724519.
GenomeReviews	Gene locus BSUW23_17555 in contig CP002183_GR.
KEGG	bss:BSUW23_17555.
PATRIC	42193279. VBIBacSub57968_3587.
Organism-specific databases
CMR	Search...
Family and domain databases
InterPro	IPR004629. WecB_TagA_CpsF. [Graphical view]
KO	K05946.
Pfam	PF03808. Glyco_tran_WecB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00696. WecB_tagA_cpsF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TARA_BACPZ

Accession

Primary (citable) accession number: Q8RKI7
Secondary accession number(s): B7ZDK9, E0U4X5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2003
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program