Reviewed, UniProtKB/Swiss-Prot Q8RHC9 (GALT_FUSNN)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	FN2108

Organism

Fusobacterium nucleatum subsp. nucleatum [Complete proteome] [HAMAP]

Taxonomic identifier

76856 [NCBI]

Taxonomic lineage

Bacteria › Fusobacteria › Fusobacterales › Fusobacteriaceae › Fusobacterium

Protein attributes

Sequence length	509 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 509	509	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169905

Sequences

	Sequence		Length	Mass (Da)
	Q8RHC9-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 80D270579047FEA1	FASTA	509	59,679
	10 20 30 40 50 60 MEICSLINRL IKYALKNSLI TEDDVMFVRN ELMALLHLKD WQDVKENCQI PEYPQEILDK 70 80 90 100 110 120 ICDYAVEQKI IEDGVTDRDI FDTEIMGKFT AFPREIIETF KELSQQNIKL ATDFFYNFSK 130 140 150 160 170 180 KTNYIRTERI EKNLYWKSLT EYGDLEITIN LSKPEKDPKE IERQKNMPQV NYPKCLLCYE 190 200 210 220 230 240 NVGFAGTLTH PARQNHRVIP LTLDNERWYF QYSPYVYYNE HAIIFCSEHR EMKINRDTFS 250 260 270 280 290 300 RTLDFINQFP HYFIGSNADL PIVGGSILSH DHYQGGNHEF PMAKSEIEKE VIFDKYPNIK 310 320 330 340 350 360 AGIVKWPMSV LRLKSLNRKD LVDLADKTLK AWREYSDEEV GVFAYTNSTP HNTITPIARK 370 380 390 400 410 420 RGDYFEIDLV LRNNRTDEAN PLGIFHPHSE HHNIKKENIG LIEVMGLAVL PGRLKFEMRK 430 440 450 460 470 480 IAEYLKDEDF EKKISDDKDT AKHLTWLKAF INKYSNLKTL SVDEILENIL NVEIGLTFSR 490 500 VLEDAGVFKR DEKGKNAFLK FINHIGGRF

References

[1]

"Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586." Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A., Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N. , D'Souza M., Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C., Overbeek R. J. Bacteriol. 184:2005-2018(2002) [PubMed: 11889109] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009951 Genomic DNA. Translation: AAL94192.1.
RefSeq	NP_602893.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	991987.
GenomeReviews	Gene locus FN2108 in contig AE009951_GR.
KEGG	fnu:FN2108.
NMPDR	fig|190304.1.peg.572.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG337915.
OMA	EHYQGGR.
Enzyme and pathway databases
BioCyc	FNUC190304:FN2108-MONOMER.
BRENDA	2.7.7.12. 289963.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_FUSNN

Accession

Primary (citable) accession number: Q8RHC9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	June 1, 2002
Last modified:	January 19, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)