Q8RF65 (GLGA_FUSNN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	FN0853

Organism

Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)

Taxonomic identifier

190304 [NCBI]

Taxonomic lineage

Bacteria › Fusobacteria › Fusobacterales › Fusobacteriaceae › Fusobacterium

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 461	461	Glycogen synthase HAMAP MF_00484		PRO_0000188616
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8RF65 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: A03722CDA94337C4	FASTA	461	53,586
	10 20 30 40 50 60 MKVLFATGEA FPFVKTGGLG DVSYSLPKTL KQKENVDIRV ILPKYSKISN ELLKDARHLG 70 80 90 100 110 120 HKEIWVAHHN EYVGIEEVEL EGVIYYFVDN ERYFKRPNVY GEFDDCERFL FFCKAVVETM 130 140 150 160 170 180 DITKFKPDII HCNDWQSALI PIYLKERGIY DVKTIFTIHN LRFQGFFFNN VIEDLLEIDR 190 200 210 220 230 240 AKYFQEDGLK YYDMISFLKG GVVYSDYITT VSDSYAEEIK TQELGEGIHG LFQKYDYKLS 250 260 270 280 290 300 GIVNGIDKIS YPLSKKPHKI LKADLQKKLG LDVEEDTPLI VIITRLDRQK GLDYIVEKFD 310 320 330 340 350 360 EMMSLGIQFI LLGTGEKRYE HFFAYQEYLH KGQVCSYIGF NQELSTEIYA GADIFLMPSV 370 380 390 400 410 420 FEPCGLSQMI AMRYGCIPVV RETGGLKDTV KPYNEYTGEG DGFGFKQANA DDMIKTLKYA 430 440 450 460 IKMYHRPNVW QEIIKNAKKR DNSWDKPAKR YKELYQRLIE G

References

[1]

"Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586." Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A., Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N. , D'Souza M., Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C., Overbeek R. J. Bacteriol. 184:2005-2018(2002) [PubMed: 11889109] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009951 Genomic DNA. Translation: AAL95049.1.
RefSeq	NP_603750.1. NC_003454.1.
3D structure databases
ProteinModelPortal	Q8RF65.
ModBase	Search...
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	993091.
GenomeReviews	Gene locus FN0853 in contig AE009951_GR.
KEGG	fnu:FN0853.
NMPDR	fig|190304.1.peg.1429.
PATRIC	21951463. VBIFusNuc122357_1414.
Phylogenomic databases
HOGENOM	HBG596384.
OMA	EALSHES.
PhylomeDB	Q8RF65.
Enzyme and pathway databases
BioCyc	FNUC190304:FN0853-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_FUSNN

Accession

Primary (citable) accession number: Q8RF65

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program