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Protein

Glycogen synthase

Gene

glgA

Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:FN0853
OrganismiFusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Taxonomic identifieri190304 [NCBI]
Taxonomic lineageiBacteriaFusobacteriaFusobacterialesFusobacteriaceaeFusobacterium
ProteomesiUP000002521 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 461461Glycogen synthasePRO_0000188616Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi190304.FN0853.

Structurei

3D structure databases

ProteinModelPortaliQ8RF65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
InParanoidiQ8RF65.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8RF65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLFATGEA FPFVKTGGLG DVSYSLPKTL KQKENVDIRV ILPKYSKISN
60 70 80 90 100
ELLKDARHLG HKEIWVAHHN EYVGIEEVEL EGVIYYFVDN ERYFKRPNVY
110 120 130 140 150
GEFDDCERFL FFCKAVVETM DITKFKPDII HCNDWQSALI PIYLKERGIY
160 170 180 190 200
DVKTIFTIHN LRFQGFFFNN VIEDLLEIDR AKYFQEDGLK YYDMISFLKG
210 220 230 240 250
GVVYSDYITT VSDSYAEEIK TQELGEGIHG LFQKYDYKLS GIVNGIDKIS
260 270 280 290 300
YPLSKKPHKI LKADLQKKLG LDVEEDTPLI VIITRLDRQK GLDYIVEKFD
310 320 330 340 350
EMMSLGIQFI LLGTGEKRYE HFFAYQEYLH KGQVCSYIGF NQELSTEIYA
360 370 380 390 400
GADIFLMPSV FEPCGLSQMI AMRYGCIPVV RETGGLKDTV KPYNEYTGEG
410 420 430 440 450
DGFGFKQANA DDMIKTLKYA IKMYHRPNVW QEIIKNAKKR DNSWDKPAKR
460
YKELYQRLIE G
Length:461
Mass (Da):53,586
Last modified:June 1, 2002 - v1
Checksum:iA03722CDA94337C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009951 Genomic DNA. Translation: AAL95049.1.
RefSeqiNP_603750.1. NC_003454.1.

Genome annotation databases

EnsemblBacteriaiAAL95049; AAL95049; FN0853.
GeneIDi993091.
KEGGifnu:FN0853.
PATRICi21951463. VBIFusNuc122357_1414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009951 Genomic DNA. Translation: AAL95049.1.
RefSeqiNP_603750.1. NC_003454.1.

3D structure databases

ProteinModelPortaliQ8RF65.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190304.FN0853.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL95049; AAL95049; FN0853.
GeneIDi993091.
KEGGifnu:FN0853.
PATRICi21951463. VBIFusNuc122357_1414.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
InParanoidiQ8RF65.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131.

Entry informationi

Entry nameiGLGA_FUSNN
AccessioniPrimary (citable) accession number: Q8RF65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: June 1, 2002
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.