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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei302NucleophileUniRule annotation1
Active sitei343Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciFNUC190304:G1FZS-1439-MONOMER
UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:FN0856
OrganismiFusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Taxonomic identifieri190304 [NCBI]
Taxonomic lineageiBacteriaFusobacteriaFusobacterialesFusobacteriaceaeFusobacterium
Proteomesi
  • UP000002521 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887081 – 6111,4-alpha-glucan branching enzyme GlgBAdd BLAST611

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi190304.FN0856

Structurei

3D structure databases

ProteinModelPortaliQ8RF62
SMRiQ8RF62
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA
HOGENOMiHOG000283037
InParanoidiQ8RF62
KOiK00700
OMAiEVVHGKS

Family and domain databases

Gene3Di2.60.40.101 hit
2.60.40.11801 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 1 hit
PfamiView protein in Pfam
PF00128 Alpha-amylase, 2 hits
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q8RF62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILMSGQMEQ YLFHRGEFRQ AYEYFGAHPT RSSTIFRIWA PSAKSVAVVG
60 70 80 90 100
DFNDWRAREE DYCHKLTNEG IWEVEIKKIK KGNLYKYQIE TSWGEKILKS
110 120 130 140 150
DPYAFYSELR PQTASIVNGK PKFRWADKRW LNNREIGYAK PINIYEVHLG
160 170 180 190 200
SWKKKEDGTY YNYKEIAELL VEYMLEMNYT HIEIMPIIEY PFDGSWGYQG
210 220 230 240 250
TGYYSVTSRY GTPDDFMYFV NYFHKNNLGV ILDWVPGHFC KDSHGLYRFD
260 270 280 290 300
GSACYEYEDP SLGENEWGSA NFNVSRNEVR SFLLSNLYFW IKEFHIDGIR
310 320 330 340 350
MDAVSNMLYY KDGLSENKHS VEFLQYLNQS LHEEYPDVML IAEDSSAWPL
360 370 380 390 400
VTKYQADGGL GFDFKWNMGW MNDTLKYMEQ DPFFRKSHHG KLTFSFMYAF
410 420 430 440 450
SENFILPLSH DEIVHGKNSI LNKMPGYYED KLAHVKNLYS YQMAHPGKKL
460 470 480 490 500
NFMGNEFVQG LEWRYYEQLE WQLLKDNKGS QDIQKYVKAL NKLYLEEEAL
510 520 530 540 550
WYDGQDGFEW IEHENINENM LIFLRKTPNM EDFIIAVFNF SGKDHEIYPL
560 570 580 590 600
GVPLEDGEYE VILDSNEKKF GGSYQGRKRK YKSIKKSWNY REQYIEIKIA
610
KNSAVFLKYK K
Length:611
Mass (Da):72,562
Last modified:June 1, 2002 - v1
Checksum:iF022C62F303CC741
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009951 Genomic DNA Translation: AAL95052.1
RefSeqiNP_603753.1, NC_003454.1
WP_011016704.1, NC_003454.1

Genome annotation databases

EnsemblBacteriaiAAL95052; AAL95052; FN0856
GeneIDi991540
KEGGifnu:FN0856
PATRICifig|190304.8.peg.1417

Similar proteinsi

Entry informationi

Entry nameiGLGB_FUSNN
AccessioniPrimary (citable) accession number: Q8RF62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: June 1, 2002
Last modified: February 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome