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Q8RDV3

- GLSA_FUSNN

UniProt

Q8RDV3 - GLSA_FUSNN

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Protein

Glutaminase

Gene

glsA

Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611SubstrateUniRule annotation
Binding sitei113 – 1131SubstrateUniRule annotation
Binding sitei158 – 1581SubstrateUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Binding sitei189 – 1891SubstrateUniRule annotation
Binding sitei240 – 2401SubstrateUniRule annotation
Binding sitei258 – 2581Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:FN1397
OrganismiFusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Taxonomic identifieri190304 [NCBI]
Taxonomic lineageiBacteriaFusobacteriaFusobacterialesFusobacteriaceaeFusobacterium
ProteomesiUP000002521: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminasePRO_0000110613Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi190304.FN1397.

Structurei

3D structure databases

ProteinModelPortaliQ8RDV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
InParanoidiQ8RDV3.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8RDV3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKELLKELVE KNRKFTADGN VANYIPELDK ADKNALGIYV TTLDGQEFFA
60 70 80 90 100
GDYNTKFTIQ SISKIISLML AILDNGEEYV FSKVGMEPSG DPFNSIRKLE
110 120 130 140 150
TSSRKKPYNP MINAGAIAVA SMIKGKDDRE KFSRLLNFAK LITEDDSLDL
160 170 180 190 200
NYKIYIGESD TGFRNYSMAY FLKGEGIIEG NVNEALTVYF KQCSIEGTAK
210 220 230 240 250
TISTLGKFLA NDGVLSNGER ILTTRMAKII KTLMVTCGMY DSSGEFAVRV
260 270 280 290 300
GIPSKSGVGG GICSVVPGKM GIGVYGPSLD KKGNSLAGGH LLEDLSAELS

LNIF
Length:304
Mass (Da):33,083
Last modified:June 1, 2002 - v1
Checksum:i35DB9C87DDE6EA57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009951 Genomic DNA. Translation: AAL95590.1.
RefSeqiNP_604291.1. NC_003454.1.

Genome annotation databases

EnsemblBacteriaiAAL95590; AAL95590; FN1397.
GeneIDi992298.
KEGGifnu:FN1397.
PATRICi21952557. VBIFusNuc122357_1958.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009951 Genomic DNA. Translation: AAL95590.1 .
RefSeqi NP_604291.1. NC_003454.1.

3D structure databases

ProteinModelPortali Q8RDV3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190304.FN1397.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL95590 ; AAL95590 ; FN1397 .
GeneIDi 992298.
KEGGi fnu:FN1397.
PATRICi 21952557. VBIFusNuc122357_1958.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
InParanoidi Q8RDV3.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131.

Entry informationi

Entry nameiGLSA_FUSNN
AccessioniPrimary (citable) accession number: Q8RDV3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3