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Q8RA71 (MUTS_THETN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length869 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity By similarity. HAMAP-Rule MF_00096

Sequence similarities

Belongs to the DNA mismatch repair MutS family.

Ontologies

Keywords
   Biological processDNA damage
DNA repair
   LigandATP-binding
DNA-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmismatch repair

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

damaged DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

mismatched DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 869869DNA mismatch repair protein MutS HAMAP-Rule MF_00096
PRO_0000115161

Regions

Nucleotide binding619 – 6268ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8RA71 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 74F6A4F5624A5882

FASTA86999,087
        10         20         30         40         50         60 
MLKMSVTPMM EQYLKIKEKY KDAILFFRLG DFYEMFYEDA EIAAKELEIA LTGRDAGTEE 

        70         80         90        100        110        120 
RAPMAGVPYH AADFYIDKLV KKGYKVAICE QLEDPSKAKG LVKRDVVRIY TPGTIINPES 

       130        140        150        160        170        180 
MDEKSNNYLV SVYREKDNYG ICAVDVTTGE LYATEIKNCK NGKRIYDEIA KYSPSEIISN 

       190        200        210        220        230        240 
EEFLKNNKYI KVFKNNNCAV NAYKPLNYEA SSELIEKQFD KKVEELELED KKFVIHSLGA 

       250        260        270        280        290        300 
LLSYLKELQK TSLKHINKLT LYQDNSYMGL DSNAIRNLEI LESNRNKSKK GSLLGVLDRT 

       310        320        330        340        350        360 
VTPMGGRLLK KWLEEPLIDK DEIEKRLDAV EELFNNYRER IELKELLNKV YDLERLASKI 

       370        380        390        400        410        420 
VYQSVTPKDF ISIKLSLQNL PKIKNILSKF SSRLLKEIYE KLDVLQDVYE LIDKSIKDDP 

       430        440        450        460        470        480 
SNQLKEGNII KDGYNEMVDK LRKASTEGKN WIANLEADER EKTGIKNLRI GYNKVFGYYI 

       490        500        510        520        530        540 
EVTKSNIPQV PDRYIRKQTL ANAERYVTPE LKEIEETILG AEEKLIELEY ELFNEIREKV 

       550        560        570        580        590        600 
ELQIVRIQNT AKYIAIIDVL ISFAEVAETN KYVKPIVDYE DRIVIKEGRH PVVETISDEG 

       610        620        630        640        650        660 
FVANDIDIGP ENPIMIITGP NMAGKSTYMR QVALIVLMAQ VGCFVPASYA RIGIVDKIFT 

       670        680        690        700        710        720 
RVGASDDIFA GQSTFMVEMS EVANILHSAT SKSLIILDEV GRGTSTYDGM SIAQAVIEYI 

       730        740        750        760        770        780 
HEKIKAKTLF ATHYHELTKL EGKLRGVRNF NVSVEEREDD IIFLHKIVPG GSDRSYGIQV 

       790        800        810        820        830        840 
SKLAGLPYSI IERAKEILEA LERDKAVKNE LEEAVSQFAF TQIDIFSSAK DALIEEIANC 

       850        860 
DPDNMTPLQA LTYLYKLKEK AASLRSGVI 

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References

[1]"A complete sequence of the T. tengcongensis genome."
Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. expand/collapse author list , Wang J., Yu J., Yang H.
Genome Res. 12:689-700(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008691 Genomic DNA. Translation: AAM24579.1.
RefSeqNP_622975.1. NC_003869.1.

3D structure databases

ProteinModelPortalQ8RA71.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273068.TTE1357.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM24579; AAM24579; TTE1357.
GeneID997769.
KEGGtte:TTE1357.
PATRIC23897428. VBITheTen82880_1367.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0249.
HOGENOMHOG000221406.
KOK03555.
OMAASMRDGG.
OrthoDBEOG6Q5NPV.

Family and domain databases

Gene3D3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00096. MutS.
InterProIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsTIGR01070. mutS1. 1 hit.
PROSITEPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMUTS_THETN
AccessionPrimary (citable) accession number: Q8RA71
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: June 1, 2002
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families