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Q8R9T6

- PKN1_CALS4

UniProt

Q8R9T6 - PKN1_CALS4

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Protein

Probable serine/threonine-protein kinase Sps1

Gene

sps1

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATPPROSITE-ProRule annotation
Active sitei134 – 1341Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase Sps1 (EC:2.7.11.1)
Gene namesi
Name:sps1
Ordered Locus Names:TTE1500
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
ProteomesiUP000000555: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 625625Probable serine/threonine-protein kinase Sps1PRO_0000171246Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273068.TTE1500.

Structurei

3D structure databases

ProteinModelPortaliQ8R9T6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 271262Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini344 – 41067PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini411 – 47767PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini478 – 54568PASTA 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 3 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiKVLRPEY.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R9T6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIGRMLGNRY EILEKIGEGG MAKVYKAKCH LLNRIVAIKI LRPEFAADEN
60 70 80 90 100
FVKKFKRESQ AAASLSHPNI VGIYDVGQEG DIYYIVMEYV KGRTLKELIR
110 120 130 140 150
ENGGPLEVKR AVEIASQVCR ALDHAHKNKI IHRDIKPQNI LVTDEDVVKV
160 170 180 190 200
TDFGIARAAN GATITYTGDV IGTAYYFSPE QAKGSIVDER TDIYSLGIVL
210 220 230 240 250
FEMLTGKVPF EGDSPISVAL KHIQEDILPP SRLNEKVPEE LDKIVLKATQ
260 270 280 290 300
KDPNLRYQTA SEFLKDLDTF LKNPKDLKFE EKDFEKTKVM PSREAEELKR
310 320 330 340 350
AALKREREKK RKEIRKKVGI VLLVLLLLAS LSYGTVYVLN NFFKVNDVVV
360 370 380 390 400
PNVVGLSLSQ ASKVLSEHNL KMEISEERYS DKPENTILEQ DPPQGALVKP
410 420 430 440 450
GTTVYVVISK GRQMVIVPNV IGRDYLEAKN VLENAGLKVN IIENYNEQYQ
460 470 480 490 500
KGYVFDQNPR YGVQVEYGTT IDVYVSKGPK PSIVPNVVNM NLDEAKASLE
510 520 530 540 550
SAGLTLGKVI YKEADNVPEN TVLEQSVPPD TEVQKGSPID LIVSKLPQNS
560 570 580 590 600
LQQQTKNVII NLPNKDGPMK VEVYVIQDGQ KNLVYSGEHT SSDSPLTVPV
610 620
TAHKGKAVIE VDIDGQVYSR VEARF
Length:625
Mass (Da):69,850
Last modified:June 1, 2002 - v1
Checksum:i2F10C267A028347E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM24718.1.
RefSeqiNP_623114.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM24718; AAM24718; TTE1500.
GeneIDi997918.
KEGGitte:TTE1500.
PATRICi23897708. VBITheTen82880_1507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM24718.1 .
RefSeqi NP_623114.1. NC_003869.1.

3D structure databases

ProteinModelPortali Q8R9T6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273068.TTE1500.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM24718 ; AAM24718 ; TTE1500 .
GeneIDi 997918.
KEGGi tte:TTE1500.
PATRICi 23897708. VBITheTen82880_1507.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi KVLRPEY.
OrthoDBi EOG6B35XT.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Entry informationi

Entry nameiPKN1_CALS4
AccessioniPrimary (citable) accession number: Q8R9T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3