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Q8R9T6

- PKN1_THETN

UniProt

Q8R9T6 - PKN1_THETN

Protein

Probable serine/threonine-protein kinase Sps1

Gene

sps1

Organism
Thermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391ATPPROSITE-ProRule annotation
    Active sitei134 – 1341Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi16 – 249ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase Sps1 (EC:2.7.11.1)
    Gene namesi
    Name:sps1
    Ordered Locus Names:TTE1500
    OrganismiThermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis)
    Taxonomic identifieri273068 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
    ProteomesiUP000000555: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 625625Probable serine/threonine-protein kinase Sps1PRO_0000171246Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273068.TTE1500.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8R9T6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 271262Protein kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini344 – 41067PASTA 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini411 – 47767PASTA 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini478 – 54568PASTA 3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 3 PASTA domains.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000037185.
    KOiK08884.
    OMAiKVLRPEY.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 3 hits.
    SM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8R9T6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIGRMLGNRY EILEKIGEGG MAKVYKAKCH LLNRIVAIKI LRPEFAADEN    50
    FVKKFKRESQ AAASLSHPNI VGIYDVGQEG DIYYIVMEYV KGRTLKELIR 100
    ENGGPLEVKR AVEIASQVCR ALDHAHKNKI IHRDIKPQNI LVTDEDVVKV 150
    TDFGIARAAN GATITYTGDV IGTAYYFSPE QAKGSIVDER TDIYSLGIVL 200
    FEMLTGKVPF EGDSPISVAL KHIQEDILPP SRLNEKVPEE LDKIVLKATQ 250
    KDPNLRYQTA SEFLKDLDTF LKNPKDLKFE EKDFEKTKVM PSREAEELKR 300
    AALKREREKK RKEIRKKVGI VLLVLLLLAS LSYGTVYVLN NFFKVNDVVV 350
    PNVVGLSLSQ ASKVLSEHNL KMEISEERYS DKPENTILEQ DPPQGALVKP 400
    GTTVYVVISK GRQMVIVPNV IGRDYLEAKN VLENAGLKVN IIENYNEQYQ 450
    KGYVFDQNPR YGVQVEYGTT IDVYVSKGPK PSIVPNVVNM NLDEAKASLE 500
    SAGLTLGKVI YKEADNVPEN TVLEQSVPPD TEVQKGSPID LIVSKLPQNS 550
    LQQQTKNVII NLPNKDGPMK VEVYVIQDGQ KNLVYSGEHT SSDSPLTVPV 600
    TAHKGKAVIE VDIDGQVYSR VEARF 625
    Length:625
    Mass (Da):69,850
    Last modified:June 1, 2002 - v1
    Checksum:i2F10C267A028347E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008691 Genomic DNA. Translation: AAM24718.1.
    RefSeqiNP_623114.1. NC_003869.1.

    Genome annotation databases

    EnsemblBacteriaiAAM24718; AAM24718; TTE1500.
    GeneIDi997918.
    KEGGitte:TTE1500.
    PATRICi23897708. VBITheTen82880_1507.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008691 Genomic DNA. Translation: AAM24718.1 .
    RefSeqi NP_623114.1. NC_003869.1.

    3D structure databases

    ProteinModelPortali Q8R9T6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273068.TTE1500.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM24718 ; AAM24718 ; TTE1500 .
    GeneIDi 997918.
    KEGGi tte:TTE1500.
    PATRICi 23897708. VBITheTen82880_1507.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000037185.
    KOi K08884.
    OMAi KVLRPEY.
    OrthoDBi EOG6B35XT.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 3 hits.
    SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

    Entry informationi

    Entry nameiPKN1_THETN
    AccessioniPrimary (citable) accession number: Q8R9T6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3