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Q8R9T6

- PKN1_THETN

UniProt

Q8R9T6 - PKN1_THETN

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Protein
Probable serine/threonine-protein kinase Sps1
Gene
sps1, TTE1500
Organism
Thermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATP By similarity
Active sitei134 – 1341Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase Sps1 (EC:2.7.11.1)
Gene namesi
Name:sps1
Ordered Locus Names:TTE1500
OrganismiThermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
ProteomesiUP000000555: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 625625Probable serine/threonine-protein kinase Sps1
PRO_0000171246Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273068.TTE1500.

Structurei

3D structure databases

ProteinModelPortaliQ8R9T6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 271262Protein kinase
Add
BLAST
Domaini344 – 41067PASTA 1
Add
BLAST
Domaini411 – 47767PASTA 2
Add
BLAST
Domaini478 – 54568PASTA 3
Add
BLAST

Sequence similaritiesi

Contains 3 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiKVLRPEY.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R9T6-1 [UniParc]FASTAAdd to Basket

« Hide

MIGRMLGNRY EILEKIGEGG MAKVYKAKCH LLNRIVAIKI LRPEFAADEN    50
FVKKFKRESQ AAASLSHPNI VGIYDVGQEG DIYYIVMEYV KGRTLKELIR 100
ENGGPLEVKR AVEIASQVCR ALDHAHKNKI IHRDIKPQNI LVTDEDVVKV 150
TDFGIARAAN GATITYTGDV IGTAYYFSPE QAKGSIVDER TDIYSLGIVL 200
FEMLTGKVPF EGDSPISVAL KHIQEDILPP SRLNEKVPEE LDKIVLKATQ 250
KDPNLRYQTA SEFLKDLDTF LKNPKDLKFE EKDFEKTKVM PSREAEELKR 300
AALKREREKK RKEIRKKVGI VLLVLLLLAS LSYGTVYVLN NFFKVNDVVV 350
PNVVGLSLSQ ASKVLSEHNL KMEISEERYS DKPENTILEQ DPPQGALVKP 400
GTTVYVVISK GRQMVIVPNV IGRDYLEAKN VLENAGLKVN IIENYNEQYQ 450
KGYVFDQNPR YGVQVEYGTT IDVYVSKGPK PSIVPNVVNM NLDEAKASLE 500
SAGLTLGKVI YKEADNVPEN TVLEQSVPPD TEVQKGSPID LIVSKLPQNS 550
LQQQTKNVII NLPNKDGPMK VEVYVIQDGQ KNLVYSGEHT SSDSPLTVPV 600
TAHKGKAVIE VDIDGQVYSR VEARF 625
Length:625
Mass (Da):69,850
Last modified:June 1, 2002 - v1
Checksum:i2F10C267A028347E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008691 Genomic DNA. Translation: AAM24718.1.
RefSeqiNP_623114.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM24718; AAM24718; TTE1500.
GeneIDi997918.
KEGGitte:TTE1500.
PATRICi23897708. VBITheTen82880_1507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008691 Genomic DNA. Translation: AAM24718.1 .
RefSeqi NP_623114.1. NC_003869.1.

3D structure databases

ProteinModelPortali Q8R9T6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273068.TTE1500.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM24718 ; AAM24718 ; TTE1500 .
GeneIDi 997918.
KEGGi tte:TTE1500.
PATRICi 23897708. VBITheTen82880_1507.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi KVLRPEY.
OrthoDBi EOG6B35XT.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Entry informationi

Entry nameiPKN1_THETN
AccessioniPrimary (citable) accession number: Q8R9T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: June 1, 2002
Last modified: September 3, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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