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Q8R965

- PGK_CALS4

UniProt

Q8R965 - PGK_CALS4

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371SubstrateUniRule annotation
Binding sitei119 – 1191SubstrateUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Binding sitei202 – 2021ATPUniRule annotation
Binding sitei293 – 2931ATP; via carbonyl oxygenUniRule annotation
Binding sitei324 – 3241ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi350 – 3534ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:TTE1761
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
ProteomesiUP000000555: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Phosphoglycerate kinasePRO_0000146028Add
BLAST

Proteomic databases

PRIDEiQ8R965.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi273068.TTE1761.

Structurei

3D structure databases

ProteinModelPortaliQ8R965.
SMRiQ8R965. Positions 1-394.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni60 – 634Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R965 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKKTVRDID VSGKRVLVRV DFNVPMDENK NITDDRRIRE ALPTIEYLIN
60 70 80 90 100
HNAKVILVSH LGRPKGKFNP DYSLKPVAKR LSELLKKPVI MAEDVIGEDA
110 120 130 140 150
KVKAAALKEG EVLLLENVRF HAEEEKNDPE FAKELASLAD IYVNDAFGTA
160 170 180 190 200
HRAHASTAGV AKYLPAVAGF LIEKELSIMG EALENPKRPF VAILGGAKVS
210 220 230 240 250
DKIGVITNLL EKVDSLLIGG GMAYTFIKAK GYEIGKSLLE EDKIELAKEI
260 270 280 290 300
MEKAKQKGVN FMLPVDTVIA KELKSGVPYE VVDIDKMPED QIGVDIGPKT
310 320 330 340 350
IEEYSKVIKH AMTVVWNGPM GVFEIPEFAK GTKAIAKALS ECKGTTIVGG
360 370 380 390
GDSAAAIEQL GYADKVTHIS TGGGASLEFL EGKVLPGIDI LNDK
Length:394
Mass (Da):42,817
Last modified:June 1, 2002 - v1
Checksum:i983EA9E59C240A32
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008691 Genomic DNA. Translation: AAM24955.1.
RefSeqiNP_623351.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM24955; AAM24955; TTE1761.
GeneIDi996811.
KEGGitte:TTE1761.
PATRICi23898265. VBITheTen82880_1770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008691 Genomic DNA. Translation: AAM24955.1 .
RefSeqi NP_623351.1. NC_003869.1.

3D structure databases

ProteinModelPortali Q8R965.
SMRi Q8R965. Positions 1-394.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273068.TTE1761.

Proteomic databases

PRIDEi Q8R965.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM24955 ; AAM24955 ; TTE1761 .
GeneIDi 996811.
KEGGi tte:TTE1761.
PATRICi 23898265. VBITheTen82880_1770.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Entry informationi

Entry nameiPGK_CALS4
AccessioniPrimary (citable) accession number: Q8R965
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3