Reviewed, UniProtKB/Swiss-Prot Q8R8W3 (SELD_THETN)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	TTE1873

Organism

Thermoanaerobacter tengcongensis [Complete proteome] [HAMAP]

Taxonomic identifier

119072 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Thermoanaerobacter

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.
Sequence caution	The sequence AAM25060.1 differs from that shown. Reason: Erroneous termination at position 16. Translated as Sec.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Selenide, water dikinase HAMAP MF_00625		PRO_0000127641
Regions
	Nucleotide binding	226 – 232	7	ATP Potential
Sites
	Active site	16	1	Potential
	Site	19	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	16	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8R8W3-1 [UniParc]. Last modified February 26, 2008. Version 3. Checksum: D7265B7FB3B82035	FASTA	344	37,570
	10 20 30 40 50 60 MIEKIKLTQF TKSAGUAAKI GPEALAQVLC QLEITWNENL LVGLNTNDDA AVYRLNEDIA 70 80 90 100 110 120 IVHTVDYFTP VVDDPYDFGQ IAAANALSDV YAMGAVPLFA LNVVCFPAAY IDVLKEVLRG 130 140 150 160 170 180 GNDKVKEAGA LIAGGHTIED EEPKYGLSVT GIVHPEKVIK NSTAKPGDVL ILTKPLGIGV 190 200 210 220 230 240 INTAIKGEMC PSETYLLAVE VMKYLNKEAS EIMKEVGVNA CTDITGFGLL GHAYEMAFSS 250 260 270 280 290 300 GVTIEFDKDS IPLIEGAREL AQMGLIPGGC YRNKKYLKGK VCIKVEEDEV IDLMFDPQTS 310 320 330 340 GGLLISVSEE KAEELYRRLN KKLKFGAFIV GRVKEKQEYD IYVR

References

[1]

"A complete sequence of the T. tengcongensis genome." Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. , Wang J., Yu J., Yang H. Genome Res. 12:689-700(2002) [PubMed: 11997336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008691 Genomic DNA. Translation: AAM25060.1. Sequence problems.
RefSeq	NP_623456.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	997067.
GenomeReviews	Gene locus TTE1873 in contig AE008691_GR.
KEGG	tte:TTE1873.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8R8W3.
Enzyme and pathway databases
BioCyc	TTEN273068:TTE1873-MON.
BRENDA	2.7.9.3. 276887.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_THETN

Accession

Primary (citable) accession number: Q8R8W3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	February 26, 2008
Last modified:	October 13, 2009
This is version 38 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)