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Q8R8R7 (GAL1_THETN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Galactokinase
EC=2.7.1.6
Alternative name(s):
Galactose kinase
Gene names
Name:galK
Ordered Locus Names:TTE1928
OrganismThermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis) [Complete proteome] [HAMAP]
Taxonomic identifier273068 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Caldanaerobacter

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate. HAMAP MF_00246

Pathway

Carbohydrate metabolism; galactose metabolism. HAMAP MF_00246

Subcellular location

Cytoplasm Potential HAMAP MF_00246.

Sequence similarities

Belongs to the GHMP kinase family. GalK subfamily.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Galactose metabolism
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgalactose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

galactokinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390Galactokinase HAMAP MF_00246
PRO_0000184633

Regions

Nucleotide binding120 – 13011ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8R8R7 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: CE70AB7110B5907D

FASTA39043,749
        10         20         30         40         50         60 
MEIAVVEALE KFYGKSDREI RLFYSPGRVN LIGEHTDYNG GYVFPCALDF GTYAAIRKRD 

        70         80         90        100        110        120 
DKKVFMASLN FDLKVEVDLD SIFYDKEHDW ANYPKGVLKI LQEEGYEFSG FEIVFGGNIP 

       130        140        150        160        170        180 
VGAGLSSSAS IEMVTAVAVN EVFNLNIDRI NLVKLCQRAE NTFVGVNCGI MDQFAVGMGK 

       190        200        210        220        230        240 
KGHAILLKSD TLEYSYVPLN LEGYKILITN TNKKRGLLDS KYNERRSECE KALTYLKKAL 

       250        260        270        280        290        300 
PVKNLSEVTV ERFEEYKDLI PDEVLRKRAR HVITENKRVL DAVKALNDND IVKFGKLMIE 

       310        320        330        340        350        360 
SHNSLRNDFE VTGKELDTLV EEALKLKGVV GSRMTGAGFG GCTVSIVKED AVEEFIEVVT 

       370        380        390 
RNYTQKIGYA PTVYVTGVGE GAGEVEYLRR

« Hide

References

[1]"A complete sequence of the T. tengcongensis genome."
Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. expand/collapse author list , Wang J., Yu J., Yang H.
Genome Res. 12:689-700(2002) [PubMed: 11997336] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE008691 Genomic DNA. Translation: AAM25107.1.
RefSeqNP_623503.1. NC_003869.1.

3D structure databases

ProteinModelPortalQ8R8R7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID997123.
GenomeReviewsGene locus TTE1928 in contig AE008691_GR.
KEGGtte:TTE1928.
NMPDRfig|273068.3.peg.1790.
PATRIC23898597. VBITheTen82880_1936.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG725121.
OMAEYVGAPT.
ProtClustDBPRK05322.

Enzyme and pathway databases

BioCycTTEN273068:TTE1928-MONOMER.

Family and domain databases

HAMAPMF_00246. Galactokinase.
[Tree]
InterProIPR000705. Galactokinase.
IPR022963. Galactokinase_bac.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00849.
PfamPF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000530. Galactokinase. 1 hit.
PRINTSPR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00131. Gal_kin. 1 hit.
PROSITEPS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGAL1_THETN
AccessionPrimary (citable) accession number: Q8R8R7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2002
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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