Q8R8R6 (GALT_THETN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase
Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	TTE1929

Organism

Thermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis) [Complete proteome] [HAMAP]

Taxonomic identifier

273068 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Caldanaerobacter

Protein attributes

Sequence length	519 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 519	519	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169922

Sequences

	Sequence		Length	Mass (Da)
	Q8R8R6 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 0BF788A4DA08ED75	FASTA	519	60,468
	10 20 30 40 50 60 MTQKDAAFHI ERLLKFALKK GLIEELDVIP SRNALMDLFK IEKPYEGEVP EEELDTPSPI 70 80 90 100 110 120 LNKLLDYGVE IGLIEDTVTY RDLMDARIMG LLMPRESEVV RKFNEIASKD GIEKATEYFY 130 140 150 160 170 180 ELSKASNYIR MDRTSQNLYW RTPTEYGALE ITINLSKPEK DPKEIEKAKK IPQSGYPKCL 190 200 210 220 230 240 LCIENVGFAG NLNHPARQNL RIIPVKVAGE QWYFQYSPYV YYNEHCILLH EEHIPMKISE 250 260 270 280 290 300 KTFVRLFDFI DQFPHYFMGS NADLPIVGGS ILVHEHFQGG RHTFPMEEAP IEEYFIHPKY 310 320 330 340 350 360 KEVKAGILKW PMSVIRLSSK DREKLTKLSS HILNVWKGYS DESVDVLAYS EKDGKIVPHN 370 380 390 400 410 420 TITPIARFNK EGEYEIDLVL RNNRTTDKYP YGIFHPHEEL HHIKKENIGL IEVMGLAVLP 430 440 450 460 470 480 GRLKFELEEI RKILTGKEKF NKDMYDENHP LYKHLHWIEE LIVKYGTHCT EEEAENYIKQ 490 500 510 EVGNKFLQVL LDAGVFKRDE KGKKAFEKFM ETAGFKKLS

References

[1]

"A complete sequence of the T. tengcongensis genome." Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. , Wang J., Yu J., Yang H. Genome Res. 12:689-700(2002) [PubMed: 11997336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008691 Genomic DNA. Translation: AAM25108.1.
RefSeq	NP_623504.1. NC_003869.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	997124.
GenomeReviews	Gene locus TTE1929 in contig AE008691_GR.
KEGG	tte:TTE1929.
NMPDR	fig|273068.3.peg.1791.
PATRIC	23898599. VBITheTen82880_1937.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG337915.
OMA	HYFIGSN.
ProtClustDB	PRK05270.
Enzyme and pathway databases
BioCyc	TTEN273068:TTE1929-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. GalT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_THETN

Accession

Primary (citable) accession number: Q8R8R6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program