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Protein

Uronate isomerase

Gene

uxaC

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:TTE1939
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
Proteomesi
  • UP000000555 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uronate isomerasePRO_0000172790Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273068.TTE1939.

Structurei

3D structure databases

ProteinModelPortaliQ8R8Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8R8Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKFMDEDFL LTNETAVKLY HQYAKDMSIY DFHCHLSPKE IYEDRRFKNI
60 70 80 90 100
TEVWLYGDHY KWRLMRANGI DEKYITGDAD DYEKFVAYAK TIPMAIGNPV
110 120 130 140 150
YHWTHLELQR YFGIYDLLNE KTAKSIWERA NEVISQEDFS ARNILKKSNV
160 170 180 190 200
KVVITTDDPV DSLEYHIKLK EEKDFDIKVL PAFRPDKGLN IEKDDFLSWI
210 220 230 240 250
KKLESASGIK ITTYDDFLQA LEKRIEFFHS VGCRISDHAL DYVFYQKTSK
260 270 280 290 300
QEAEKVFKKV LTEQHLTKEE IDSFKTYTMI FLGKKYAELN WVMQLHIGAM
310 320 330 340 350
RNNNTKMYRI LGPDTGYDSI GDFPIAYSLS RLLDSLEIEG ALPKTILYTL
360 370 380 390 400
NPAANYVIAT MIGNFQDGKI AGKMQFGAAW WFNDNKDGIK EQLKTLANVG
410 420 430 440 450
LLGRFVGMVT DSRSFLSYAR HEYFRRILCD LIGEWVENGE VPNDIELLGK
460
IVQDISFNNA KEYMGV
Length:466
Mass (Da):54,325
Last modified:June 1, 2002 - v1
Checksum:i7DA89D68B258EFB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM25118.1.
RefSeqiWP_011026082.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM25118; AAM25118; TTE1939.
KEGGitte:TTE1939.
PATRICi23898619. VBITheTen82880_1947.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM25118.1.
RefSeqiWP_011026082.1. NC_003869.1.

3D structure databases

ProteinModelPortaliQ8R8Q6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273068.TTE1939.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM25118; AAM25118; TTE1939.
KEGGitte:TTE1939.
PATRICi23898619. VBITheTen82880_1947.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_CALS4
AccessioniPrimary (citable) accession number: Q8R8Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.