Q8R8M3 (COMB_THETN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	TTE1972

Organism

Thermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis) [Complete proteome] [HAMAP]

Taxonomic identifier

273068 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Caldanaerobacter

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081479

Sequences

	Sequence		Length	Mass (Da)
	Q8R8M3 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 101C39E246E79969	FASTA	241	27,221
	10 20 30 40 50 60 MFLQTYETYN SINDRDLKEK NVVVIDTLRA TSVITTALFN GAKEVIPVSE VEEAIELSKN 70 80 90 100 110 120 FDRDTFLLAG ERNSQKIEGF DLSNSPLEYV PEKVKGKTII FTTTNGTRAL KKVASAEEVI 130 140 150 160 170 180 LGCLLNVSAV ARYISKSNKD TVIVCAGTEG KFSFDDILTA GAIYEKLKSL TDFESDDLSK 190 200 210 220 230 240 ASYFLYKPYE NNLYDIMKYG YHLRRLEELG YTEDIKFCLT VDKFDIVPKL KNGIVRTSQD F

References

[1]

"A complete sequence of the T. tengcongensis genome." Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. , Wang J., Yu J., Yang H. Genome Res. 12:689-700(2002) [PubMed: 11997336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008691 Genomic DNA. Translation: AAM25151.1.
RefSeq	NP_623547.1. NC_003869.1.
3D structure databases
ProteinModelPortal	Q8R8M3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	997168.
GenomeReviews	Gene locus TTE1972 in contig AE008691_GR.
KEGG	tte:TTE1972.
NMPDR	fig|273068.3.peg.1942.
PATRIC	23898691. VBITheTen82880_1983.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG633644.
OMA	GWEGAYS.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	TTEN273068:TTE1972-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_THETN

Accession

Primary (citable) accession number: Q8R8M3

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program