Reviewed, UniProtKB/Swiss-Prot Q8R8M3 (COMB_THETN)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	TTE1972

Organism

Thermoanaerobacter tengcongensis [Complete proteome] [HAMAP]

Taxonomic identifier

119072 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Thermoanaerobacter

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081479

Sequences

	Sequence		Length	Mass (Da)
	Q8R8M3-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 101C39E246E79969	FASTA	241	27,221
	10 20 30 40 50 60 MFLQTYETYN SINDRDLKEK NVVVIDTLRA TSVITTALFN GAKEVIPVSE VEEAIELSKN 70 80 90 100 110 120 FDRDTFLLAG ERNSQKIEGF DLSNSPLEYV PEKVKGKTII FTTTNGTRAL KKVASAEEVI 130 140 150 160 170 180 LGCLLNVSAV ARYISKSNKD TVIVCAGTEG KFSFDDILTA GAIYEKLKSL TDFESDDLSK 190 200 210 220 230 240 ASYFLYKPYE NNLYDIMKYG YHLRRLEELG YTEDIKFCLT VDKFDIVPKL KNGIVRTSQD F

References

[1]

"A complete sequence of the T. tengcongensis genome." Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R. , Wang J., Yu J., Yang H. Genome Res. 12:689-700(2002) [PubMed: 11997336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15242 / JCM 11007 / NBRC 100824 / MB4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013149 Genomic DNA. Translation: AAM25151.1.
RefSeq	NP_623547.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	997168.
GenomeReviews	Gene locus TTE1972 in contig AE008691_GR.
KEGG	tte:TTE1972.
NMPDR	fig|273068.3.peg.1942.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8R8M3.
OMA	Q8R8M3. ATTTIAW.
Enzyme and pathway databases
BioCyc	TTEN273068:TTE1972-MON.
BRENDA	3.1.3.71. 276887.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_THETN

Accession

Primary (citable) accession number: Q8R8M3

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2002
Last sequence update:	June 1, 2002
Last modified:	June 16, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)