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Protein
Submitted name:

Hypoxanthine-guanine phosphoribosyltransferase

Gene

Hpt

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi101MagnesiumCombined sources1
Metal bindingi102MagnesiumCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Keywords - Ligandi

MagnesiumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BRENDAi2.4.2.8. 6784.
SABIO-RKQ8R7L0.

Names & Taxonomyi

Protein namesi
Submitted name:
Hypoxanthine-guanine phosphoribosyltransferaseImported
Gene namesi
Name:HptImported
Ordered Locus Names:TTE2394Imported
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)Imported
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
Proteomesi
  • UP000000555 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8R7L0.

Interactioni

Protein-protein interaction databases

STRINGi273068.TTE2394.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1R3UX-ray2.50A/B1-181[»]
1YFZX-ray2.20A/B1-181[»]
2GEBX-ray1.70A1-181[»]
ProteinModelPortaliQ8R7L0.
SMRiQ8R7L0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8R7L0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 162PribosyltranInterPro annotationAdd BLAST147

Phylogenomic databases

eggNOGiENOG4108UGV. Bacteria.
COG0634. LUCA.
HOGENOMiHOG000236520.
KOiK00760.
OMAiTPVTMDW.
OrthoDBiPOG091H02F3.

Family and domain databases

CDDicd06223. PRTases_typeI. 1 hit.
Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8R7L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPMEDIEE ILITEEQLKA KVKELGEMIT RDYEGKDLVL IGVLKGAIMF
60 70 80 90 100
MSDLSRAIDL PLSIDFMAVS SYGSSTKSSG IVKIIKDHDI DIEGKDVLIV
110 120 130 140 150
EDIIDSGLTL AYLRETLLGR KPRSLKICTI LDKPERREAD VKVDYCGFKI
160 170 180
PDKFVVGYGL DYAEKYRNLP FIGVLKPELY K
Length:181
Mass (Da):20,379
Last modified:June 1, 2002 - v1
Checksum:i4B9907E434A093E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM25533.1.
RefSeqiWP_011026425.1. NC_003869.1.

Genome annotation databases

EnsemblBacteriaiAAM25533; AAM25533; TTE2394.
KEGGitte:TTE2394.
PATRICi23899523. VBITheTen82880_2384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA. Translation: AAM25533.1.
RefSeqiWP_011026425.1. NC_003869.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1R3UX-ray2.50A/B1-181[»]
1YFZX-ray2.20A/B1-181[»]
2GEBX-ray1.70A1-181[»]
ProteinModelPortaliQ8R7L0.
SMRiQ8R7L0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273068.TTE2394.

Proteomic databases

PRIDEiQ8R7L0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM25533; AAM25533; TTE2394.
KEGGitte:TTE2394.
PATRICi23899523. VBITheTen82880_2384.

Phylogenomic databases

eggNOGiENOG4108UGV. Bacteria.
COG0634. LUCA.
HOGENOMiHOG000236520.
KOiK00760.
OMAiTPVTMDW.
OrthoDBiPOG091H02F3.

Enzyme and pathway databases

BRENDAi2.4.2.8. 6784.
SABIO-RKQ8R7L0.

Miscellaneous databases

EvolutionaryTraceiQ8R7L0.
PROiQ8R7L0.

Family and domain databases

CDDicd06223. PRTases_typeI. 1 hit.
Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8R7L0_CALS4
AccessioniPrimary (citable) accession number: Q8R7L0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: November 2, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.