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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTTEN273068:G1FZJ-2729-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:TTE2533
OrganismiCaldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)
Taxonomic identifieri273068 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeCaldanaerobacter
Proteomesi
  • UP000000555 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516291 – 562Arginine--tRNA ligaseAdd BLAST562

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi273068.TTE2533

Structurei

3D structure databases

ProteinModelPortaliQ8R786
SMRiQ8R786
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi136 – 146"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q8R786-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENIVQKAKE EIKDVVLKAL NEAKKEGLLN FESIQDVEVE EPKEKQHGDL
60 70 80 90 100
ATNFAMVMAR EAKMAPRKIA EIIASKMNTS GTFIEKVEVA GPGFINFFLN
110 120 130 140 150
QNFLIETLKL IHKRGKDYGR VNLGKGKKVQ VEFVSANPTG PMHMGNARGG
160 170 180 190 200
AIGDVLASIL DYAGYNVSRE FYINDAGNQI EKFGYSLEAR YLQLLGIDAE
210 220 230 240 250
VPEGGYHGED IIDRAKEFLE IHGDKYKDVP SEERRKALIE YGLKKNIEKM
260 270 280 290 300
KEDLVLYGIE YDVWFSEQSL YDSGEVYKVI EELTEKGYTY EKDGALWFKM
310 320 330 340 350
TLFGAEKDDV LVRSNGVPTY LASDIAYHKN KFVTRGFDWV INVWGADHHG
360 370 380 390 400
HVAPMKGAMK ALGIDPNRLD VVLMQLVKLI EGGQVVRMSK RTGKMITLRD
410 420 430 440 450
LIEEVGKDAA RFFFNMRSPD SPIEFDLDLA KQQTNENPVF YVQYAHARIC
460 470 480 490 500
SIIRQLEEMG VKIENIEDVD LGLLKEEEEV DLIKKLAYFP EEITIAAKTL
510 520 530 540 550
APHRITRYVI DVASLFHSFY NSHRVKGAEE NLMKARFALI LAVKTVLKNA
560
LDILKVTAPE RM
Length:562
Mass (Da):63,693
Last modified:June 1, 2002 - v1
Checksum:i5F49126E19BDC08B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008691 Genomic DNA Translation: AAM25662.1
RefSeqiWP_011026543.1, NC_003869.1

Genome annotation databases

EnsemblBacteriaiAAM25662; AAM25662; TTE2533
KEGGitte:TTE2533

Similar proteinsi

Entry informationi

Entry nameiSYR_CALS4
AccessioniPrimary (citable) accession number: Q8R786
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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