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Q8R691 (Q8R691_FUSNN) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase HAMAP MF_00388
EC=3.5.1.- HAMAP MF_00388
Alternative name(s):
UDP-3-O-acyl-GlcNAc deacetylase HAMAP MF_00388
Gene names
Name:lpxC HAMAP MF_00388
Ordered Locus Names:FN0593
OrganismFusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131) EMBL AAL94789.1
Taxonomic identifier190304 [NCBI]
Taxonomic lineageBacteria › Fusobacteria › Fusobacterales › Fusobacteriaceae › Fusobacterium

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00388

Catalytic activity

UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. HAMAP MF_00388

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. HAMAP MF_00388

Sequence similarities

Belongs to the LpxC family. HAMAP MF_00388

Sequences

Sequence LengthMass (Da)Tools
Q8R691 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: CB109E6BBEE9D25E

FASTA28332,267
        10         20         30         40         50         60 
MNRKGNMKRK TLKNIVEYDG IGLHKGEIIK MKLIPAKSGG IIFRMVNMPE GKNEILLDYR 

        70         80         90        100        110        120 
NIFDLTRGTN LKNEHGAMVF TIEHFLSALY VLGITDLVIE LNGNELPICD GSAIKFLDLF 

       130        140        150        160        170        180 
QESGIVELDE YVEEIIVKEP IFLSKGDKHV IALPYPDGYK LTYAIRFEHT FLKSQLAEFE 

       190        200        210        220        230        240 
ITEKNYRKEI ASARTFGFDY EVEYLKQNNL ALGGTLENAI VIKKDGVLNP DGLRFDDEFV 

       250        260        270        280 
RHKMLDIIGD LKILNRPIRA HIIAIKAGHL IDIEFAKILD NIK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE009951 Genomic DNA. Translation: AAL94789.1.
RefSeqNP_603490.1. NC_003454.1.

3D structure databases

HSSPHSSP built from PDB template 1P42 based on UniProtKB O67648.
ProteinModelPortalQ8R691.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID991847.
GenomeReviewsGene locus FN0593 in contig AE009951_GR.
KEGGfnu:FN0593.
NMPDRfig|190304.1.peg.1169.
PATRIC21950951. VBIFusNuc122357_1158.

Phylogenomic databases

HOGENOMHBG482342.
OMAKAYKSGH.
PhylomeDBQ8R691.
ProtClustDBPRK13186.

Family and domain databases

HAMAPMF_00388. LpxC.
[Tree]
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR004463. UDP-acyl_GlcNac_deAcase.
IPR011334. UDP-acyl_GlcNac_deAcase_C.
IPR015870. UDP-acyl_N-AcGlcN_deAcase_N.
[Graphical view]
Gene3DG3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit.
G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KOK02535.
PfamPF03331. LpxC. 1 hit.
[Graphical view]
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMsTIGR00325. LpxC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8R691_FUSNN
AccessionPrimary (citable) accession number: Q8R691
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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