Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

Preferred order of sections

Names and origin

Protein names

Recommended name:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

Alternative name(s):
Centaurin-delta-3
Short name=Cnt-d3
Dual specificity Rho- and Arf-GTPase-activating protein 1

Gene names

Name:	Arap3
Synonyms:	Centd3, Drag1, Kiaa4097

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1538 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts preferentially on ARF5 and on RHOA. Ref.1
Subunit structure	Interacts with INPPL1/SHIP2 By similarity.
Subcellular location	Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm › cytoskeleton. Cell projection › lamellipodium. Cell projection › ruffle. Note: Cytoplasmic, and associated with F-actin-rich membrane ruffles and lamellipodia. Ref.1
Post-translational modification	Tyrosine phosphorylated at a low basal level. PDGF treatment stimulates phosphorylation. Tyrosine phosphorylation is increased in cells that are in the process of becoming attached to a substrate and that start spreading and flattening. Ref.1 Ref.5
Sequence similarities	Contains 1 Arf-GAP domain. Contains 5 PH domains. Contains 1 Ras-associating domain. Contains 1 Rho-GAP domain. Contains 1 SAM (sterile alpha motif) domain.
Sequence caution	The sequence AAL78678.1 differs from that shown. Reason: Erroneous initiation. The sequence BAD90507.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell membrane Cell projection Cytoplasm Cytoskeleton Membrane
Coding sequence diversity	Alternative splicing
Domain	Repeat
Molecular function	GTPase activation
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	negative regulation of Rac protein signal transduction Inferred from direct assay Ref.1. Source: MGI negative regulation of Rho protein signal transduction Inferred from direct assay Ref.1. Source: MGI negative regulation of cell migration Inferred from direct assay Ref.1. Source: MGI regulation of ARF GTPase activity Inferred from electronic annotation. Source: InterPro regulation of cell shape Inferred from direct assay Ref.1. Source: MGI signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell lamellipodium Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell ruffle Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ARF GTPase activator activity Inferred from electronic annotation. Source: InterPro Rho GTPase activator activity Inferred from direct assay Ref.1. Source: MGI protein binding Inferred from physical interaction Ref.1. Source: IntAct zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
LYN	P07948	2	EBI-621463,EBI-79452	From a different organism.
SRC	P12931	3	EBI-621463,EBI-621482	From a different organism.

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8R5G7-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8R5G7-2) Also known as: ARAP3 delta-SAM; The sequence of this isoform differs from the canonical sequence as follows: 1-78: Missing.

Isoform 3 (identifier: Q8R5G7-3) The sequence of this isoform differs from the canonical sequence as follows: 1-618: Missing. 1446-1538: KASMLGHEER...SNPPSSQPLT → GPSPFVCTMKSLKEGEG
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1538

1538

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

PRO_0000074216

Regions

Domain

4 – 68

65

SAM

Domain

282 – 374

93

PH 1

Domain

389 – 478

90

PH 2

Domain

479 – 606

128

Arf-GAP

Domain

671 – 785

115

PH 3

Domain

795 – 901

107

PH 4

Domain

903 – 1084

182

Rho-GAP

Domain

1113 – 1206

94

Ras-associating

Domain

1219 – 1321

103

PH 5

Compositional bias

1493 – 1536

44

Pro-rich

Amino acid modifications

Modified residue

1399

1

Phosphotyrosine Ref.1

Modified residue

1404

1

Phosphotyrosine Ref.1 Ref.5

Modified residue

1438

1

Phosphoserine By similarity

Natural variations

Alternative sequence

1 – 618

618

Missing in isoform 3.

VSP_015002

Alternative sequence

1 – 78

78

Missing in isoform 2.

VSP_015003

Alternative sequence

1446 – 1538

93

KASML…SQPLT → GPSPFVCTMKSLKEGEG in isoform 3.

VSP_015004

Experimental info

Mutagenesis

938

1

R → L: Loss of Rho GAP activity. Enhances cell spreading. Ref.1

Mutagenesis

1399

1

Y → F: Strongly reduces phosphorylation by CSK; when associated with F-1404. Ref.1

Mutagenesis

1404

1

Y → F: Strongly reduces phosphorylation by CSK; when associated with F-1399. Ref.1

Sequence conflict

144

1

Q → H in AAH68145. Ref.3

Sequence conflict

167

1

R → Q in AAL78677. Ref.1

Sequence conflict

167

1

R → Q in AAL78678. Ref.1

Sequence conflict

1304

1

M → T in AAL78677. Ref.1

Sequence conflict

1304

1

M → T in AAL78678. Ref.1

Sequence conflict

1500

1

S → P in AAL78677. Ref.1

Sequence conflict

1500

1

S → P in AAL78678. Ref.1

Sequences

Sequence		Length	Mass (Da)
Isoform 1 [UniParc]. Last modified July 27, 2011. Version 3. Checksum: D7E55C57FD4B83ED Show »	FASTA	1,538	169,741
10 20 30 40 50 60 MAAPQDLDIA VWLALVHLEQ YADTFRRHGL ATAGAAQHLG HEELRHLGIS ATGHRKRILR 70 80 90 100 110 120 LLRAGSAEGF LDSHLDNTME PTPSPAPDAQ PPKPVPKPRT VFGLSNPATA QRPGLSPIFW 130 140 150 160 170 180 DPEVSRNSEC TQRSSPLLPS SSEQPSVPNT MEMMPNAIYF GLDLRGRAQA AQDVTPDSSQ 190 200 210 220 230 240 ATVPTPAFRP TTGTVHIMDP GCLYYGVQPV GIPGASDRRD GRGVCQERAE HRQDLETRED 250 260 270 280 290 300 AGYASLELPG DSILSLPTQD AETSDDLISP YASFSSTADR PVPLLSGWLD KLSPQGNYVF 310 320 330 340 350 360 QRRFVQFNGR SLMYFGSDKD PFPKGVIPLT AIEMTRSSKD NKFQVITGQR VFVFRTESEA 370 380 390 400 410 420 QRDLWCSTLQ SCLKEQRLLG HPRPPHPPRP LRTGTLELRG HKAKVFAALI PGELALYKSE 430 440 450 460 470 480 QAFSLGIGIC FIELQGCSVR ETKSRSFDLL TPHRCFSFTA ESGGARQSWA AALQEAVTET 490 500 510 520 530 540 LSDYEVAEKV WSNPANRHCA DCRASRPDWA AVNLGVVICK QCAGQHRALG SGISKVQSLK 550 560 570 580 590 600 LDTSVWSNEI VQLFIVLGND RANCFWAGAL PPGEGLHPDS APGPRGEFIS RKYKLGLFRK 610 620 630 640 650 660 PHPRHPDHSQ LLQALCAAMA GPNLLKNMAQ LLCVETSEGE EPLSPSALNG SLLSLLPSDS 670 680 690 700 710 720 PGVYNEVVVP ATYRGFLYCG SISNKAGAPP LRRGRDAPPR LWCVLGAALE MFASESSPEP 730 740 750 760 770 780 LSLLQPQDIV CLGVSPPPAD PGDLDRFPFS FELILTGGRI QHFATDGADS LEAWISAVGK 790 800 810 820 830 840 WFSPLSCHQL LGPGLLRMGR LWLRSPSHAG LAPGLWLSGF GLLRGDHLFL CPAPGPGPPA 850 860 870 880 890 900 PEDMVHLRRL QEISVVSAAD TPDKKEHLVL VETGRTLYLQ GEGRLDFAAW NTAIGGAAGG 910 920 930 940 950 960 GGTGLQEQQM SRGDIPIIVD ACISFVTQHG LRLEGVYRKG GARARSLRLL AEFRRDARSV 970 980 990 1000 1010 1020 KLRPREHFVE DVTDTLKRFF RELDDPVTSA RLLPRWREAA ELSQKNQRLE KYKEVISCLP 1030 1040 1050 1060 1070 1080 RVNRRTLATL IGHLYRVQKC ASLNQMCTRN LALLFAPSVF QTDGRGEHEV RVLQELIDGY 1090 1100 1110 1120 1130 1140 ISVFDIDSDQ AAQIDLEVSL ITTWKDVQLS QAGDLIMEVY IEQQLPDNCV TLKVSPTLTA 1150 1160 1170 1180 1190 1200 EELTNQVLEM RGAASGTDLW VTFEILEHGE LERPLHPKEK VLEQALQWCQ LPEPCSASLL 1210 1220 1230 1240 1250 1260 LRKVSMAHAG CLFTGVRRES PRVGLLRCRE EPPRLLGNRF QERFFLVRGR CLLLLKEKKS 1270 1280 1290 1300 1310 1320 SKPEREWSLE GAKVYLGIRK KLKPPTLWGF TLILEKMHLC LSCMDEEEMW DWTTSILKAQ 1330 1340 1350 1360 1370 1380 HDDQQSVVLR RRSSSDLARQ KFGTMPLLPI RGDDSGATLL SANQTLRRLH NRRTLSMFFP 1390 1400 1410 1420 1430 1440 MKSPQGSVEE QDELEEPVYE EPVYEEVGAF PELTKDTTFS STWEWSAKSD PSLTSQRSFD 1450 1460 1470 1480 1490 1500 QPPLSKASML GHEERIPDPP PGPPSKSSSQ ARGSLEEQLL QELNNLILRK GEPASCPESS 1510 1520 1530 SQPTSPQAPS PTSLPTPTPS LPTQPPCTSN PPSSQPLT « Hide
Isoform 2 (ARAP3 delta-SAM) [UniParc]. Checksum: C00130DB36CA8116 Show »	FASTA	1,460	161,171
10 20 30 40 50 60 MEPTPSPAPD AQPPKPVPKP RTVFGLSNPA TAQRPGLSPI FWDPEVSRNS ECTQRSSPLL 70 80 90 100 110 120 PSSSEQPSVP NTMEMMPNAI YFGLDLRGRA QAAQDVTPDS SQATVPTPAF RPTTGTVHIM 130 140 150 160 170 180 DPGCLYYGVQ PVGIPGASDR RDGRGVCQER AEHRQDLETR EDAGYASLEL PGDSILSLPT 190 200 210 220 230 240 QDAETSDDLI SPYASFSSTA DRPVPLLSGW LDKLSPQGNY VFQRRFVQFN GRSLMYFGSD 250 260 270 280 290 300 KDPFPKGVIP LTAIEMTRSS KDNKFQVITG QRVFVFRTES EAQRDLWCST LQSCLKEQRL 310 320 330 340 350 360 LGHPRPPHPP RPLRTGTLEL RGHKAKVFAA LIPGELALYK SEQAFSLGIG ICFIELQGCS 370 380 390 400 410 420 VRETKSRSFD LLTPHRCFSF TAESGGARQS WAAALQEAVT ETLSDYEVAE KVWSNPANRH 430 440 450 460 470 480 CADCRASRPD WAAVNLGVVI CKQCAGQHRA LGSGISKVQS LKLDTSVWSN EIVQLFIVLG 490 500 510 520 530 540 NDRANCFWAG ALPPGEGLHP DSAPGPRGEF ISRKYKLGLF RKPHPRHPDH SQLLQALCAA 550 560 570 580 590 600 MAGPNLLKNM AQLLCVETSE GEEPLSPSAL NGSLLSLLPS DSPGVYNEVV VPATYRGFLY 610 620 630 640 650 660 CGSISNKAGA PPLRRGRDAP PRLWCVLGAA LEMFASESSP EPLSLLQPQD IVCLGVSPPP 670 680 690 700 710 720 ADPGDLDRFP FSFELILTGG RIQHFATDGA DSLEAWISAV GKWFSPLSCH QLLGPGLLRM 730 740 750 760 770 780 GRLWLRSPSH AGLAPGLWLS GFGLLRGDHL FLCPAPGPGP PAPEDMVHLR RLQEISVVSA 790 800 810 820 830 840 ADTPDKKEHL VLVETGRTLY LQGEGRLDFA AWNTAIGGAA GGGGTGLQEQ QMSRGDIPII 850 860 870 880 890 900 VDACISFVTQ HGLRLEGVYR KGGARARSLR LLAEFRRDAR SVKLRPREHF VEDVTDTLKR 910 920 930 940 950 960 FFRELDDPVT SARLLPRWRE AAELSQKNQR LEKYKEVISC LPRVNRRTLA TLIGHLYRVQ 970 980 990 1000 1010 1020 KCASLNQMCT RNLALLFAPS VFQTDGRGEH EVRVLQELID GYISVFDIDS DQAAQIDLEV 1030 1040 1050 1060 1070 1080 SLITTWKDVQ LSQAGDLIME VYIEQQLPDN CVTLKVSPTL TAEELTNQVL EMRGAASGTD 1090 1100 1110 1120 1130 1140 LWVTFEILEH GELERPLHPK EKVLEQALQW CQLPEPCSAS LLLRKVSMAH AGCLFTGVRR 1150 1160 1170 1180 1190 1200 ESPRVGLLRC REEPPRLLGN RFQERFFLVR GRCLLLLKEK KSSKPEREWS LEGAKVYLGI 1210 1220 1230 1240 1250 1260 RKKLKPPTLW GFTLILEKMH LCLSCMDEEE MWDWTTSILK AQHDDQQSVV LRRRSSSDLA 1270 1280 1290 1300 1310 1320 RQKFGTMPLL PIRGDDSGAT LLSANQTLRR LHNRRTLSMF FPMKSPQGSV EEQDELEEPV 1330 1340 1350 1360 1370 1380 YEEPVYEEVG AFPELTKDTT FSSTWEWSAK SDPSLTSQRS FDQPPLSKAS MLGHEERIPD 1390 1400 1410 1420 1430 1440 PPPGPPSKSS SQARGSLEEQ LLQELNNLIL RKGEPASCPE SSSQPTSPQA PSPTSLPTPT 1450 1460 PSLPTQPPCT SNPPSSQPLT « Hide
Isoform 3 [UniParc]. Checksum: 5742FA191BD0F796 Show »	FASTA	844	94,043
10 20 30 40 50 60 MAGPNLLKNM AQLLCVETSE GEEPLSPSAL NGSLLSLLPS DSPGVYNEVV VPATYRGFLY 70 80 90 100 110 120 CGSISNKAGA PPLRRGRDAP PRLWCVLGAA LEMFASESSP EPLSLLQPQD IVCLGVSPPP 130 140 150 160 170 180 ADPGDLDRFP FSFELILTGG RIQHFATDGA DSLEAWISAV GKWFSPLSCH QLLGPGLLRM 190 200 210 220 230 240 GRLWLRSPSH AGLAPGLWLS GFGLLRGDHL FLCPAPGPGP PAPEDMVHLR RLQEISVVSA 250 260 270 280 290 300 ADTPDKKEHL VLVETGRTLY LQGEGRLDFA AWNTAIGGAA GGGGTGLQEQ QMSRGDIPII 310 320 330 340 350 360 VDACISFVTQ HGLRLEGVYR KGGARARSLR LLAEFRRDAR SVKLRPREHF VEDVTDTLKR 370 380 390 400 410 420 FFRELDDPVT SARLLPRWRE AAELSQKNQR LEKYKEVISC LPRVNRRTLA TLIGHLYRVQ 430 440 450 460 470 480 KCASLNQMCT RNLALLFAPS VFQTDGRGEH EVRVLQELID GYISVFDIDS DQAAQIDLEV 490 500 510 520 530 540 SLITTWKDVQ LSQAGDLIME VYIEQQLPDN CVTLKVSPTL TAEELTNQVL EMRGAASGTD 550 560 570 580 590 600 LWVTFEILEH GELERPLHPK EKVLEQALQW CQLPEPCSAS LLLRKVSMAH AGCLFTGVRR 610 620 630 640 650 660 ESPRVGLLRC REEPPRLLGN RFQERFFLVR GRCLLLLKEK KSSKPEREWS LEGAKVYLGI 670 680 690 700 710 720 RKKLKPPTLW GFTLILEKMH LCLSCMDEEE MWDWTTSILK AQHDDQQSVV LRRRSSSDLA 730 740 750 760 770 780 RQKFGTMPLL PIRGDDSGAT LLSANQTLRR LHNRRTLSMF FPMKSPQGSV EEQDELEEPV 790 800 810 820 830 840 YEEPVYEEVG AFPELTKDTT FSSTWEWSAK SDPSLTSQRS FDQPPLSGPS PFVCTMKSLK EGEG « Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner." Stacey T.T.I., Nie Z., Stewart A., Najdovska M., Hall N.E., He H., Randazzo P.A., Lock P. J. Cell Sci. 117:6071-6084(2004) [PubMed: 15546919] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, MUTAGENESIS OF ARG-938; TYR-1399 AND TYR-1404, PHOSPHORYLATION AT TYR-1399 AND TYR-1404, SUBCELLULAR LOCATION. Strain: NIH Swiss. Tissue: Embryo.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: C57BL/6. Tissue: Brain.
[4]	"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O., Koga H. Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 619-1538 (ISOFORM 3). Tissue: Brain.
[5]	"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling." Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., Kawakami T., Salomon A.R. J. Immunol. 179:5864-5876(2007) [PubMed: 17947660] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1404, MASS SPECTROMETRY. Tissue: Mast cell.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF469621 mRNA. Translation: AAL78677.1. AF469622 mRNA. Translation: AAL78678.1. Different initiation. AC121886 Genomic DNA. No translation available. AC129315 Genomic DNA. No translation available. BC068145 mRNA. Translation: AAH68145.1. AK220486 mRNA. Translation: BAD90507.1. Different initiation.
IPI	IPI00469281. IPI00648850. IPI00649097.
RefSeq	NP_001192265.1. NM_001205336.1. NP_631945.2. NM_139206.2.
UniGene	Mm.247642.
3D structure databases
ProteinModelPortal	Q8R5G7.
SMR	Q8R5G7. Positions 1-80.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8R5G7. 2 interactions.
STRING	Q8R5G7.
PTM databases
PhosphoSite	Q8R5G7.
Proteomic databases
PRIDE	Q8R5G7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000042944; ENSMUSP00000035662; ENSMUSG00000024451.
GeneID	106952.
KEGG	mmu:106952.
UCSC	uc008erq.2. mouse. uc008err.2. mouse.
Organism-specific databases
CTD	64411.
MGI	MGI:2147274. Arap3.
Rouge	Search...
Phylogenomic databases
GeneTree	ENSGT00600000084201.
HOGENOM	HBG446850.
HOVERGEN	HBG069114.
InParanoid	Q8R5G7.
OrthoDB	EOG4G4GPK.
Gene expression databases
ArrayExpress	Q8R5G7.
Bgee	Q8R5G7.
Genevestigator	Q8R5G7.
GermOnline	ENSMUSG00000024451. Mus musculus.
Family and domain databases
InterPro	IPR001164. ArfGAP. IPR011993. PH_type. IPR001849. Pleckstrin_homology. IPR000159. Ras-assoc. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. IPR001660. SAM. IPR013761. SAM/pointed. IPR011510. SAM_2. [Graphical view]
Gene3D	G3DSA:2.30.29.30. PH_type. 4 hits. G3DSA:1.10.555.10. RhoGAP. 1 hit. G3DSA:1.10.150.50. SAM_type. 1 hit.
KO	K12490.
Pfam	PF01412. ArfGap. 1 hit. PF00169. PH. 1 hit. PF00788. RA. 1 hit. PF00620. RhoGAP. 1 hit. PF07647. SAM_2. 1 hit. [Graphical view]
PRINTS	PR00405. REVINTRACTNG.
SMART	SM00105. ArfGap. 1 hit. SM00233. PH. 5 hits. SM00324. RhoGAP. 1 hit. SM00454. SAM. 1 hit. [Graphical view]
SUPFAM	SSF57863. ArfGAP. 1 hit. SSF48350. Rho_GAP. 1 hit. SSF47769. SAM_homology. 1 hit.
PROSITE	PS50115. ARFGAP. 1 hit. PS50003. PH_DOMAIN. 3 hits. PS50200. RA. 1 hit. PS50238. RHOGAP. 1 hit. PS50105. SAM_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	358482.
SOURCE	Search...

Entry information

Entry name

ARAP3_MOUSE

Accession

Primary (citable) accession number: Q8R5G7
Secondary accession number(s): E9QMK7

Q8R5G6

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	July 27, 2011
Last modified:	November 16, 2011
This is version 90 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Alternative products

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Natural variations

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents