##gff-version 3
Q8R4P5	UniProtKB	Chain	1	757	.	.	.	ID=PRO_0000185381;Note=Transmembrane channel-like protein 1	
Q8R4P5	UniProtKB	Topological domain	1	193	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	194	214	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	215	266	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	267	287	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	288	359	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	360	380	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	381	434	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	435	455	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	456	631	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	632	652	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	653	696	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Transmembrane	697	717	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Topological domain	718	757	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8R4P5	UniProtKB	Region	1	74	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8R4P5	UniProtKB	Region	81	130	.	.	.	Note=Required for interaction with CIB2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28663585;Dbxref=PMID:28663585	
Q8R4P5	UniProtKB	Region	298	352	.	.	.	Note=Required for interaction with CIB2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Compositional bias	20	44	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8R4P5	UniProtKB	Compositional bias	53	74	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8R4P5	UniProtKB	Alternative sequence	1	545	.	.	.	ID=VSP_006435;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:16141072;Dbxref=PMID:16141072	
Q8R4P5	UniProtKB	Alternative sequence	546	562	.	.	.	ID=VSP_006436;Note=In isoform 2. FVRFCNYCWCWDLEYGY->MQQIPDALHSSPIALYE;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:16141072;Dbxref=PMID:16141072	
Q8R4P5	UniProtKB	Alternative sequence	751	757	.	.	.	ID=VSP_006437;Note=In isoform 2. AAAAGGQ->GWRCGFVWRFCVPNSPYTLALPMRHSMARHHRPWELIPRFLPSIISDLPKHLSEALISFPWEWIKKKKKDGKFQ;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:16141072;Dbxref=PMID:16141072	
Q8R4P5	UniProtKB	Natural variant	412	412	.	.	.	Note=In BTH. M->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11850623;Dbxref=PMID:11850623	
Q8R4P5	UniProtKB	Mutagenesis	312	312	.	.	.	Note=Disrupts interaction with CIB2 and CIB3. F->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	315	315	.	.	.	Note=Disrupts interaction with CIB2 and CIB3. W->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	317	317	.	.	.	Note=Disrupts interaction with CIB2 and CIB3. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	321	321	.	.	.	Note=No impact on interaction with CIB2 and CIB3. N->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	323	323	.	.	.	Note=No impact on interaction with CIB2 and CIB3. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	332	332	.	.	.	Note=Disrupts interaction with CIB2 and CIB3. I->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	336	336	.	.	.	Note=Disrupts interaction with CIB2 and CIB3. F->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Mutagenesis	337	337	.	.	.	Note=No impact on interaction with CIB2 and CIB3. K->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34089643;Dbxref=PMID:34089643	
Q8R4P5	UniProtKB	Helix	306	312	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WUD	
Q8R4P5	UniProtKB	Helix	322	346	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WUD