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Q8R4G7

- Q8R4G7_RAT

UniProt

Q8R4G7 - Q8R4G7_RAT

Protein
Submitted name:

Transforming growth factor-beta type II receptor

Gene

Tgfbr2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. glycosaminoglycan binding Source: Ensembl
    2. transforming growth factor beta-activated receptor activity Source: Ensembl

    GO - Biological processi

    1. activation of protein kinase activity Source: Ensembl
    2. brain development Source: Ensembl
    3. bronchus morphogenesis Source: Ensembl
    4. cartilage development Source: Ensembl
    5. embryonic cranial skeleton morphogenesis Source: Ensembl
    6. embryonic hemopoiesis Source: Ensembl
    7. gastrulation Source: Ensembl
    8. heart development Source: Ensembl
    9. in utero embryonic development Source: Ensembl
    10. lens development in camera-type eye Source: Ensembl
    11. lens fiber cell apoptotic process Source: Ensembl
    12. lung lobe morphogenesis Source: Ensembl
    13. mammary gland morphogenesis Source: Ensembl
    14. myeloid dendritic cell differentiation Source: Ensembl
    15. palate development Source: Ensembl
    16. pathway-restricted SMAD protein phosphorylation Source: Ensembl
    17. patterning of blood vessels Source: Ensembl
    18. peptidyl-serine phosphorylation Source: Ensembl
    19. peptidyl-threonine phosphorylation Source: Ensembl
    20. positive regulation of B cell tolerance induction Source: Ensembl
    21. positive regulation of epithelial cell migration Source: Ensembl
    22. positive regulation of mesenchymal cell proliferation Source: Ensembl
    23. positive regulation of NK T cell differentiation Source: Ensembl
    24. positive regulation of reactive oxygen species metabolic process Source: Ensembl
    25. positive regulation of T cell tolerance induction Source: Ensembl
    26. positive regulation of tolerance induction to self antigen Source: Ensembl
    27. response to cholesterol Source: Ensembl
    28. response to drug Source: Ensembl
    29. smoothened signaling pathway Source: Ensembl
    30. trachea formation Source: Ensembl
    31. transforming growth factor beta receptor signaling pathway Source: Ensembl
    32. vasculogenesis Source: Ensembl

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Transforming growth factor-beta type II receptorImported
    Gene namesi
    Name:Tgfbr2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi69651. Tgfbr2.

    Subcellular locationi

    GO - Cellular componenti

    1. caveola Source: Ensembl
    2. external side of plasma membrane Source: Ensembl
    3. integral component of membrane Source: Ensembl
    4. receptor complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ8R4G7.
    GenevestigatoriQ8R4G7.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000231495.
    InParanoidiQ8R4G7.

    Sequencei

    Sequence statusi: Fragment.

    Q8R4G7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRGLLRGLW PLHIVLWTRI ASTIPPHVPK S                       31
    Length:31
    Mass (Da):3,503
    Last modified:June 1, 2002 - v1
    Checksum:i6BD2D2AE85396B5F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei31 – 311Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF474028 Genomic DNA. Translation: AAL82610.1.
    UniGeneiRn.9954.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF474028 Genomic DNA. Translation: AAL82610.1 .
    UniGenei Rn.9954.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 69651. Tgfbr2.

    Phylogenomic databases

    HOGENOMi HOG000231495.
    InParanoidi Q8R4G7.

    Gene expression databases

    ArrayExpressi Q8R4G7.
    Genevestigatori Q8R4G7.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Transcriptional and post-transcriptional regulation of transforming growth factor beta type II receptor expression in osteoblasts."
      Chang W., Parra M., Ji C., Liu Y., Eickelberg O., McCarthy T.L., Centrella M.
      Gene 299:65-77(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiQ8R4G7_RAT
    AccessioniPrimary (citable) accession number: Q8R4G7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)