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Q8R4G7

- Q8R4G7_RAT

UniProt

Q8R4G7 - Q8R4G7_RAT

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Protein
Submitted name: Transforming growth factor-beta type II receptor
Gene
Tgfbr2
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. glycosaminoglycan binding Source: Ensembl
  2. transforming growth factor beta-activated receptor activity Source: Ensembl

GO - Biological processi

  1. activation of protein kinase activity Source: Ensembl
  2. brain development Source: Ensembl
  3. bronchus morphogenesis Source: Ensembl
  4. cartilage development Source: Ensembl
  5. embryonic cranial skeleton morphogenesis Source: Ensembl
  6. embryonic hemopoiesis Source: Ensembl
  7. gastrulation Source: Ensembl
  8. heart development Source: Ensembl
  9. in utero embryonic development Source: Ensembl
  10. lens development in camera-type eye Source: Ensembl
  11. lens fiber cell apoptotic process Source: Ensembl
  12. lung lobe morphogenesis Source: Ensembl
  13. mammary gland morphogenesis Source: Ensembl
  14. myeloid dendritic cell differentiation Source: Ensembl
  15. palate development Source: Ensembl
  16. pathway-restricted SMAD protein phosphorylation Source: Ensembl
  17. patterning of blood vessels Source: Ensembl
  18. peptidyl-serine phosphorylation Source: Ensembl
  19. peptidyl-threonine phosphorylation Source: Ensembl
  20. positive regulation of B cell tolerance induction Source: Ensembl
  21. positive regulation of NK T cell differentiation Source: Ensembl
  22. positive regulation of T cell tolerance induction Source: Ensembl
  23. positive regulation of epithelial cell migration Source: Ensembl
  24. positive regulation of mesenchymal cell proliferation Source: Ensembl
  25. positive regulation of reactive oxygen species metabolic process Source: Ensembl
  26. positive regulation of tolerance induction to self antigen Source: Ensembl
  27. response to cholesterol Source: Ensembl
  28. response to drug Source: Ensembl
  29. smoothened signaling pathway Source: Ensembl
  30. trachea formation Source: Ensembl
  31. transforming growth factor beta receptor signaling pathway Source: Ensembl
  32. vasculogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor-beta type II receptorImported
Gene namesi
Name:Tgfbr2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi69651. Tgfbr2.

Subcellular locationi

GO - Cellular componenti

  1. caveola Source: Ensembl
  2. external side of plasma membrane Source: Ensembl
  3. integral component of membrane Source: Ensembl
  4. receptor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ8R4G7.
GenevestigatoriQ8R4G7.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000231495.
InParanoidiQ8R4G7.

Sequencei

Sequence statusi: Fragment.

Q8R4G7-1 [UniParc]FASTAAdd to Basket

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MGRGLLRGLW PLHIVLWTRI ASTIPPHVPK S                       31
Length:31
Mass (Da):3,503
Last modified:June 1, 2002 - v1
Checksum:i6BD2D2AE85396B5F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei31 – 311Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF474028 Genomic DNA. Translation: AAL82610.1.
UniGeneiRn.9954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF474028 Genomic DNA. Translation: AAL82610.1 .
UniGenei Rn.9954.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 69651. Tgfbr2.

Phylogenomic databases

HOGENOMi HOG000231495.
InParanoidi Q8R4G7.

Gene expression databases

ArrayExpressi Q8R4G7.
Genevestigatori Q8R4G7.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Transcriptional and post-transcriptional regulation of transforming growth factor beta type II receptor expression in osteoblasts."
    Chang W., Parra M., Ji C., Liu Y., Eickelberg O., McCarthy T.L., Centrella M.
    Gene 299:65-77(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ8R4G7_RAT
AccessioniPrimary (citable) accession number: Q8R4G7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: July 9, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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