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Protein
Submitted name:

Cadherin 13

Gene

Cdh13

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_312354. Adherens junctions interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin 13Imported
Submitted name:
Protein Cdh13Imported
Submitted name:
T-cadherinImported
Gene namesi
Name:Cdh13Imported
ORF Names:rCG_51389Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi619745. Cdh13.

Subcellular locationi

GO - Cellular componenti

  • caveola Source: Ensembl
  • external side of plasma membrane Source: Ensembl
  • extracellular exosome Source: Ensembl
  • extracellular space Source: Ensembl
  • focal adhesion Source: Ensembl
  • neuron projection Source: Ensembl
  • perinuclear region of cytoplasm Source: RGD
  • plasma membrane Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

MembraneSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019298.

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiNOG304703.
GeneTreeiENSGT00760000118906.
HOGENOMiHOG000231254.
HOVERGENiHBG106438.
KOiK06808.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR014868. Cadherin_pro_dom.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08758. Cadherin_pro. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
SM01055. Cadherin_pro. 1 hit.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R490-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPRTPLTLC VLLSQVLLVT SAGDLDCTPG FQQKVLHIHQ PAEFIEDQPV
60 70 80 90 100
LNLTFSDCKG NKKLHYEVSS PYFKVNSDGT LVAVRNITAV GRTLFVHART
110 120 130 140 150
PHAEDMAELV IVGGKDIQGS LQDIFKFART SPVPRQKRSI VVSPILIPEN
160 170 180 190 200
QRQPFPRDVG KVVDSDRPEG SKFRLTGKGV DQDPKGTFRI NENTGSVSVT
210 220 230 240 250
RTLDRETIAT YQLFVETTDA SGRTLEGPVP LEVIVIDQND NRPIFREGPY
260 270 280 290 300
IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
310 320 330 340 350
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT
360 370 380 390 400
IVIDDKNDHS PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PATGAWRAAY
410 420 430 440 450
TIINGNPGQS FEIHTNPQTN EGMLSVVKPL DYEISAFHTL LIKVENEDPL
460 470 480 490 500
VPDVSYGPSS TATVHITVLD VNEGPVFYPD PMMVTKQENI SVGSVLLTVN
510 520 530 540 550
ATDPDSLQHQ TIRYSVYKDP AGWLSINPIN GTVDTTAVLD RESPFVHNSV
560 570 580 590 600
YTALFLAIDS GNPPATGTGT LMITLEDVND NAPVIYPTVA EVCDDARNLS
610 620 630 640 650
VVILGASDKD LHPNTDPFKF EIHKQTVPDK VWKISKINNT HALVSLLQNL
660 670 680 690 700
NKANYNLPIM VTDSGKPPMT NITDLRVQVC SCKNSKVDCN AAGTLHLSLS
710
LLLLFSLLSL LSGL
Length:714
Mass (Da):78,086
Last modified:June 1, 2002 - v1
Checksum:i7E56142B8162F864
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07043979 Genomic DNA. No translation available.
AABR07043980 Genomic DNA. No translation available.
AABR07043981 Genomic DNA. No translation available.
AABR07043982 Genomic DNA. No translation available.
AABR07043983 Genomic DNA. No translation available.
AABR07043984 Genomic DNA. No translation available.
AABR07043985 Genomic DNA. No translation available.
AABR07043986 Genomic DNA. No translation available.
AABR07043987 Genomic DNA. No translation available.
AABR07043988 Genomic DNA. No translation available.
AABR07043989 Genomic DNA. No translation available.
AABR07043990 Genomic DNA. No translation available.
AABR07043991 Genomic DNA. No translation available.
AABR07043992 Genomic DNA. No translation available.
AABR07043993 Genomic DNA. No translation available.
AABR07043994 Genomic DNA. No translation available.
AABR07043995 Genomic DNA. No translation available.
AABR07043996 Genomic DNA. No translation available.
AABR07043997 Genomic DNA. No translation available.
AABR07043998 Genomic DNA. No translation available.
AABR07043999 Genomic DNA. No translation available.
AABR07044000 Genomic DNA. No translation available.
AABR07044001 Genomic DNA. No translation available.
BC085699 mRNA. Translation: AAH85699.1.
AF494095 mRNA. Translation: AAM14607.1.
CH473972 Genomic DNA. Translation: EDL92658.1.
RefSeqiNP_620244.1. NM_138889.2.
UniGeneiRn.23806.

Genome annotation databases

EnsembliENSRNOT00000077053; ENSRNOP00000068368; ENSRNOG00000014371.
GeneIDi192248.
KEGGirno:192248.
UCSCiRGD:619745. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07043979 Genomic DNA. No translation available.
AABR07043980 Genomic DNA. No translation available.
AABR07043981 Genomic DNA. No translation available.
AABR07043982 Genomic DNA. No translation available.
AABR07043983 Genomic DNA. No translation available.
AABR07043984 Genomic DNA. No translation available.
AABR07043985 Genomic DNA. No translation available.
AABR07043986 Genomic DNA. No translation available.
AABR07043987 Genomic DNA. No translation available.
AABR07043988 Genomic DNA. No translation available.
AABR07043989 Genomic DNA. No translation available.
AABR07043990 Genomic DNA. No translation available.
AABR07043991 Genomic DNA. No translation available.
AABR07043992 Genomic DNA. No translation available.
AABR07043993 Genomic DNA. No translation available.
AABR07043994 Genomic DNA. No translation available.
AABR07043995 Genomic DNA. No translation available.
AABR07043996 Genomic DNA. No translation available.
AABR07043997 Genomic DNA. No translation available.
AABR07043998 Genomic DNA. No translation available.
AABR07043999 Genomic DNA. No translation available.
AABR07044000 Genomic DNA. No translation available.
AABR07044001 Genomic DNA. No translation available.
BC085699 mRNA. Translation: AAH85699.1.
AF494095 mRNA. Translation: AAM14607.1.
CH473972 Genomic DNA. Translation: EDL92658.1.
RefSeqiNP_620244.1. NM_138889.2.
UniGeneiRn.23806.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019298.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000077053; ENSRNOP00000068368; ENSRNOG00000014371.
GeneIDi192248.
KEGGirno:192248.
UCSCiRGD:619745. rat.

Organism-specific databases

CTDi1012.
RGDi619745. Cdh13.

Phylogenomic databases

eggNOGiNOG304703.
GeneTreeiENSGT00760000118906.
HOGENOMiHOG000231254.
HOVERGENiHBG106438.
KOiK06808.

Enzyme and pathway databases

ReactomeiREACT_312354. Adherens junctions interactions.

Miscellaneous databases

NextBioi622888.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR014868. Cadherin_pro_dom.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08758. Cadherin_pro. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
SM01055. Cadherin_pro. 1 hit.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of rat T-cadherin."
    Niermann T., Schmutz S.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HeartImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.
  3. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  6. Ensembl
    Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ8R490_RAT
AccessioniPrimary (citable) accession number: Q8R490
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: July 22, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.