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Protein
Submitted name:

SGLT3-a

Gene

Slc5a4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. hydrogen ion transmembrane transporter activity Source: MGI

GO - Biological processi

  1. hydrogen ion transmembrane transport Source: GOC
  2. proton transport Source: MGI
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SGLT3-aImported
Gene namesi
Name:Slc5a4aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927848. Slc5a4a.

Subcellular locationi

Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ8R479.
ExpressionAtlasiQ8R479. baseline and differential.
GenevestigatoriQ8R479.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020450.

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG101080.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
PROSITEiPS00457. NA_SOLUT_SYMP_2. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8R479-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
QLVHYTEAIS SYLGPPIAAV FLVAVFCKRA NEQGAFWGLM VGLVMGLIRM
60 70 80 90 100
IAEFSYGTGS CLAPSSCPKI ICGVHYLYFA IILFFVCILV ILGVSYLTKP
110 120 130 140 150
IPDVHLHRLC WALRNSKEER IDLDAEDKEE NGADDRTEED QTEKPRGCLK
160 170 180 190 200
KTCDLFCGLQ RAEFKLTKVE EEALTDTTEK PFWRTVMNVN VILLLAVAAF

FYGYFA
Length:206
Mass (Da):23,177
Last modified:June 1, 2002 - v1
Checksum:i5B2EADF86F09CFDD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498304 mRNA. Translation: AAM18100.1.
UniGeneiMm.154797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498304 mRNA. Translation: AAM18100.1.
UniGeneiMm.154797.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020450.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1927848. Slc5a4a.

Phylogenomic databases

HOVERGENiHBG101080.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ8R479.
ExpressionAtlasiQ8R479. baseline and differential.
GenevestigatoriQ8R479.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
PROSITEiPS00457. NA_SOLUT_SYMP_2. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Mouse kidney expresses mRNA of four highly related sodium-glucose cotransporters: regulation by cadmium."
    Tabatabai N.M., Blumenthal S.S., Lewand D.L., Petering D.H.
    Kidney Int. 64:1320-1330(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ8R479_MOUSE
AccessioniPrimary (citable) accession number: Q8R479
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: January 7, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.