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Protein

Interferon alpha-inducible protein 27-like protein 2A

Gene

Ifi27l2a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

  • aging Source: MGI
  • response to virus Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Interferon alpha-inducible protein 27-like protein 2A
Alternative name(s):
Interferon-stimulated gene 12 protein
Short name:
ISG12
Gene namesi
Name:Ifi27l2a
Synonyms:Ifi27, Isg12
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1924183. Ifi27l2a.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalSequence analysisAdd
BLAST
Transmembranei67 – 8923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 9066Interferon alpha-inducible protein 27-like protein 2APRO_0000416107Add
BLAST

Proteomic databases

PaxDbiQ8R412.

PTM databases

PhosphoSiteiQ8R412.

Expressioni

Gene expression databases

BgeeiENSMUSG00000079017.
GenevisibleiQ8R412. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054698.

Structurei

3D structure databases

ProteinModelPortaliQ8R412.
SMRiQ8R412. Positions 23-90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IFI6/IFI27 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000002592.
HOGENOMiHOG000112988.
InParanoidiQ8R412.
OMAiSSAMAEC.
TreeFamiTF340510.

Family and domain databases

InterProiIPR009311. IFI6/IFI27.
[Graphical view]
PANTHERiPTHR16932. PTHR16932. 1 hit.
PfamiPF06140. Ifi-6-16. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8R412-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGTLFGSAI GGALAVAGAP VALAAMGFTG TGIAAASIAA KMMSAAAIAN
60 70 80 90
GGGVAAGSLV ATLQSAGVLG LSTSTNAILG AAGAAVGALL
Length:90
Mass (Da):7,929
Last modified:June 1, 2002 - v1
Checksum:iE4EEE1E956031607
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK160503 mRNA. Translation: BAE35827.1.
AC154347 Genomic DNA. No translation available.
CH466549 Genomic DNA. Translation: EDL18827.1.
BC100588 mRNA. Translation: AAI00589.1.
AY090098 mRNA. Translation: AAM10443.1.
BN000231 mRNA. Translation: CAE00398.1.
CCDSiCCDS49153.1.
RefSeqiNP_084079.1. NM_029803.3.
UniGeneiMm.271275.
Mm.446878.

Genome annotation databases

EnsembliENSMUST00000055071; ENSMUSP00000054698; ENSMUSG00000079017.
GeneIDi76933.
KEGGimmu:76933.
UCSCiuc007ovn.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK160503 mRNA. Translation: BAE35827.1.
AC154347 Genomic DNA. No translation available.
CH466549 Genomic DNA. Translation: EDL18827.1.
BC100588 mRNA. Translation: AAI00589.1.
AY090098 mRNA. Translation: AAM10443.1.
BN000231 mRNA. Translation: CAE00398.1.
CCDSiCCDS49153.1.
RefSeqiNP_084079.1. NM_029803.3.
UniGeneiMm.271275.
Mm.446878.

3D structure databases

ProteinModelPortaliQ8R412.
SMRiQ8R412. Positions 23-90.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054698.

PTM databases

PhosphoSiteiQ8R412.

Proteomic databases

PaxDbiQ8R412.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000055071; ENSMUSP00000054698; ENSMUSG00000079017.
GeneIDi76933.
KEGGimmu:76933.
UCSCiuc007ovn.3. mouse.

Organism-specific databases

CTDi76933.
MGIiMGI:1924183. Ifi27l2a.

Phylogenomic databases

GeneTreeiENSGT00390000002592.
HOGENOMiHOG000112988.
InParanoidiQ8R412.
OMAiSSAMAEC.
TreeFamiTF340510.

Miscellaneous databases

ChiTaRSiIfi27l2a. mouse.
PROiQ8R412.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000079017.
GenevisibleiQ8R412. MM.

Family and domain databases

InterProiIPR009311. IFI6/IFI27.
[Graphical view]
PANTHERiPTHR16932. PTHR16932. 1 hit.
PfamiPF06140. Ifi-6-16. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIF27A_MOUSE
AccessioniPrimary (citable) accession number: Q8R412
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.