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Q8R3U8

- Q8R3U8_MOUSE

UniProt

Q8R3U8 - Q8R3U8_MOUSE

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Protein
Submitted name:

Mapkapk2 protein

Gene

Mapkapk2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: Ensembl

GO - Biological processi

  1. 3'-UTR-mediated mRNA stabilization Source: Ensembl
  2. cellular response to vascular endothelial growth factor stimulus Source: Ensembl
  3. G2 DNA damage checkpoint Source: Ensembl
  4. inner ear development Source: MGI
  5. mRNA stabilization Source: MGI
  6. peptidyl-serine phosphorylation Source: Ensembl
  7. regulation of tumor necrosis factor production Source: Ensembl
  8. response to cytokine Source: Ensembl
  9. vascular endothelial growth factor receptor signaling pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mapkapk2 proteinImported
Gene namesi
Name:Mapkapk2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109298. Mapkapk2.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: Ensembl
  2. cytoplasm Source: MGI
  3. nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8R3U8.

Expressioni

Gene expression databases

BgeeiQ8R3U8.
ExpressionAtlasiQ8R3U8. baseline and differential.
GenevestigatoriQ8R3U8.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000016672.

Structurei

3D structure databases

ProteinModelPortaliQ8R3U8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG106948.

Family and domain databases

Gene3Di4.10.1170.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR027442. MAPKAPK_C.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8R3U8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LTTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG YPPFYSNHGL
60 70 80 90 100
AISPGMKTRI RMGQYEFPNP EWSEVSEEVK MLIRNLLKTE PTQRMTITEF
110 120 130 140 150
MNHPWIMQST KVPQTPLHTS RVLKEDKERW EDVKEEMTSA LATMRVDYEQ
160 170 180
IKIKKIEDAS NPLLLKRRKK ARAVEDAALA H
Length:181
Mass (Da):21,070
Last modified:June 1, 2002 - v1
Checksum:iE603176BDB1443C9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC024559 mRNA. Translation: AAH24559.1.
UniGeneiMm.221235.
Mm.490983.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC024559 mRNA. Translation: AAH24559.1 .
UniGenei Mm.221235.
Mm.490983.

3D structure databases

ProteinModelPortali Q8R3U8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000016672.

Proteomic databases

PRIDEi Q8R3U8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:109298. Mapkapk2.

Phylogenomic databases

HOVERGENi HBG106948.

Miscellaneous databases

ChiTaRSi MAPKAPK2. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q8R3U8.
ExpressionAtlasi Q8R3U8. baseline and differential.
Genevestigatori Q8R3U8.

Family and domain databases

Gene3Di 4.10.1170.10. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR027442. MAPKAPK_C.
IPR000719. Prot_kinase_dom.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N-3Imported.
    Tissue: Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by biopsy.Imported.

Entry informationi

Entry nameiQ8R3U8_MOUSE
AccessioniPrimary (citable) accession number: Q8R3U8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)