Q8R3U8 (Q8R3U8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mapkapk2 protein EMBL AAH24559.1

Gene names

Name:

Mapkapk2 EMBL AAH24559.1 MGI 109298

Organism

Mus musculus (Mouse) EMBL AAH24559.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	181 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	3'-UTR-mediated mRNA stabilization Inferred from electronic annotation. Source: Compara G2 DNA damage checkpoint Inferred from electronic annotation. Source: Compara cellular response to vascular endothelial growth factor stimulus Inferred from electronic annotation. Source: Compara inner ear development Inferred from direct assay PubMed 21795542. Source: MGI mRNA stabilization Inferred from mutant phenotype PubMed 11741878. Source: MGI peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara regulation of tumor necrosis factor production Inferred from electronic annotation. Source: Compara vascular endothelial growth factor receptor signaling pathway Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from direct assay PubMed 15538386. Source: MGI nucleus Inferred from direct assay PubMed 15538386. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH24559.1

Sequences

	Sequence		Length	Mass (Da)
	Q8R3U8 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: E603176BDB1443C9	FASTA	181	21,070
	10 20 30 40 50 60 LTTPCYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG YPPFYSNHGL AISPGMKTRI 70 80 90 100 110 120 RMGQYEFPNP EWSEVSEEVK MLIRNLLKTE PTQRMTITEF MNHPWIMQST KVPQTPLHTS 130 140 150 160 170 180 RVLKEDKERW EDVKEEMTSA LATMRVDYEQ IKIKKIEDAS NPLLLKRRKK ARAVEDAALA H

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: FVB/N-3 EMBL AAH24559.1. Tissue: Mammary tumor. MMTV-LTR/INT3 model. 5 month old mouse. Taken by biopsy. EMBL AAH24559.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC024559 mRNA. Translation: AAH24559.1.
IPI	IPI00113079.
UniGene	Mm.221235. Mm.490983.
3D structure databases
HSSP	HSSP built from PDB template 1KWP based on UniProtKB P49137.
ProteinModelPortal	Q8R3U8.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000016672. Q8R3U8.
Proteomic databases
PRIDE	Q8R3U8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:109298. Mapkapk2.
Phylogenomic databases
HOVERGEN	HBG106948.
InParanoid	Q8R3U8.
Gene expression databases
ArrayExpress	Q8R3U8.
Bgee	Q8R3U8.
Genevestigator	Q8R3U8.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	MAPKAPK2. mouse.
SOURCE	Search...

Entry information

Entry name

Q8R3U8_MOUSE

Accession

Primary (citable) accession number: Q8R3U8

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)