Unreviewed, UniProtKB/TrEMBL Q8R382 (Q8R382_MOUSE)

Names and origin

Protein names

Submitted name:
    Frizzled homolog 6 (Drosophila) EMBL AAH26150.1

Gene names

Name:

Fzd6 EMBL AAH26150.1

Organism

Mus musculus (Mouse) EMBL AAH26150.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	709 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 FZ (frizzled) domain.

Ontologies

Keywords
Biological process	Wnt signaling pathway Spearmint SPM017981
Cellular component	Membrane
Domain	Transmembrane Spearmint SPM000539
Molecular function	Developmental protein Spearmint SPM000539 G-protein coupled receptor Spearmint SPM000539 Receptor Transducer
Gene Ontology (GO)
Biological process	G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW non-G-protein coupled 7TM receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8R382-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 03C5FA90977119D7	FASTA	709	79,093
	10 20 30 40 50 60 MERSPFLLAC ILLPLVRGHS LFTCEPITVP RCMKMTYNMT FFPNLMGHYD QGIAAVEMGH 70 80 90 100 110 120 FLHLANLECS PNIEMFLCQA FIPTCTEQIH VVLPCRKLCE KIVSDCKKLM DTFGIRWPEE 130 140 150 160 170 180 LECNRLPHCD DTVPVTSHPH TELSGPQKKS DQVPRDIGFW CPKHLRTSGD QGYRFLGIEQ 190 200 210 220 230 240 CAPPCPNMYF KSDELDFAKS FIGIVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC 250 260 270 280 290 300 YSIVSLMYFV GFLLGNSTAC NKADEKLELG DTVVLGSKNK ACSVVFMFLY FFTMAGTVWW 310 320 330 340 350 360 VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGAPGFLTV MLLAMNKVEG DNISGVCFVG 370 380 390 400 410 420 LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 430 440 450 460 470 480 SGLYLVPLVT LLGCYVYELV NRITWEMTWF SDHCHQYRIP CPYQANPKAR PELALFMIKY 490 500 510 520 530 540 LMTLIVGISA VFWVGSKKTC TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK 550 560 570 580 590 600 KKHGAPGPHR LKVISKSMGT STGATTNHGT SAMAIADHDY LGQETSTEVH TSPEASVKEG 610 620 630 640 650 660 RADRANTPSA KDRDCGEPAG PSSKLSGDRN GRESRAGGLK ERSNGSEGAP SEGRVSPKSS 670 680 690 700 VPETGLIDCS TSQAASSPEP TSLKGSTSLP VHSASRARKE QGAGSHSDA

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Czech II EMBL AAH26150.1. Tissue: Mammary tumor metastatized to lung. Tumor arose spontaneously EMBL AAH26150.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC026150 mRNA. Translation: AAH26150.1.
IPI	IPI00117095.
UniGene	Mm.4769
3D structure databases
HSSP	HSSP built from PDB template 1IJY based on UniProtKB Q61091.
SMR	Q8R382. Positions 23-133.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8R382.
Genome annotation databases
Ensembl	ENSMUST00000022906; ENSMUSP00000022906; ENSMUSG00000022297; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:108474. Fzd6.
Phylogenomic databases
HOVERGEN	Q8R382.
InParanoid	Q8R382.
Gene expression databases
ArrayExpress	Q8R382.
Bgee	Q8R382.
Genevestigator	Q8R382.
Family and domain databases
InterPro	IPR000539. Frizzled. IPR020067. Frizzled-like_dom. IPR000024. Frizzled_Cys-rich. IPR020068. Frizzled_dom_subgr. IPR015526. Frizzled_related. IPR017981. GPCR_2-like. [Graphical view]
Gene3D	G3DSA:1.10.2000.10. Frizzled_Cys-rich. 1 hit.
PANTHER	PTHR11309. Fz_related. 1 hit.
Pfam	PF01534. Frizzled. 1 hit. PF01392. Fz. 1 hit. [Graphical view]
PRINTS	PR00489. FRIZZLED.
SMART	SM00063. FRI. 1 hit. [Graphical view]
PROSITE	PS50038. FZ. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	285845.
SOURCE	Search...

Entry information

Entry name

Q8R382_MOUSE

Accession

Primary (citable) accession number: Q8R382

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	February 9, 2010
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)