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Q8R311 (CTGE5_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
cTAGE family member 5

Short name=Protein cTAGE-5
Alternative name(s):
Meningioma-expressed antigen 6
Gene names
Name:Ctage5
Synonyms:Mea6, Mgea6
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length779 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the cTAGE family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainCoiled coil
Transmembrane
Transmembrane helix
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 779779cTAGE family member 5
PRO_0000189542

Regions

Transmembrane10 – 3021Helical; Potential
Coiled coil62 – 250189 Potential
Coiled coil297 – 470174 Potential
Compositional bias531 – 5366Poly-Gly
Compositional bias652 – 774123Pro-rich

Amino acid modifications

Modified residue5141Phosphoserine Ref.2 Ref.3 Ref.4
Modified residue5261Phosphoserine Ref.4
Modified residue5611Phosphoserine Ref.3
Modified residue6541Phosphoserine Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q8R311 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 77F6FC898BA833D8

FASTA77987,718
        10         20         30         40         50         60 
MRADFNPSGF SLELAVCVLS VGLLAVVLFL WRGFRSIRSR FYVGREKKLA LELSALIEEK 

        70         80         90        100        110        120 
CKLLDKVSIV QKEYEGLESS LKEASFEKES TEAQSLEFVE GSQISEATYE NLEQSKSKLE 

       130        140        150        160        170        180 
DEILLLEEKL EEERAKHSEQ DELMADISKR IQSLEDESKS LKSQVAEAKT TFRIFEINEE 

       190        200        210        220        230        240 
RLKGAIKDAL NENSQLQESQ KQLLQETEMM KEQVNDLDKQ KVALEESRAQ AEQALSEKES 

       250        260        270        280        290        300 
QIETLVTSLL KMKDWAAVLG EDIADDGNLD LDMKSGLENT AALDNQPKGA LKKLIYAAKL 

       310        320        330        340        350        360 
NASLKALEGE RNQVYTQLSE VDQVKEDLTE HIKSLESKQA SLQSEKTEFE SESQKLQQKL 

       370        380        390        400        410        420 
KVITELYQEN EMKLHRKLTV EENYRLEKEE KLSKVDEKIS HATEELETCR QRAKDLEEEL 

       430        440        450        460        470        480 
ERTIHSYQGQ VISHEKKAHD NWLAARTLER NLNDLRKENA HNRQKLTETE FKFELLEKDP 

       490        500        510        520        530        540 
YALDVPNTAF GREHSPYGPS PLGRPPSETR AFLSPPTLLE GPLRLSPLLP GGGGRGSRGP 

       550        560        570        580        590        600 
ENLLDHQMNT ERGESSYDRL SDAPRAPSDR SLSPPWEQDR RMTAHPPPGQ PYSDPALQRQ 

       610        620        630        640        650        660 
DRFYPNSGRL SGPAELRSYN MPSLDKVDGP VPSEMESSGN GTKDNLGNSN VPDSPIPAEC 

       670        680        690        700        710        720 
EAAGRGFFPP PFPPVRDPLF PVDPRSQFMR RGPSFPPPPP GSIYAAPRDY FPPRDFPGPP 

       730        740        750        760        770 
LPPFPGRTVY APRGFPPYLP PRAGFFPPPP HPESRSELPP DLIPPSKEPA ADPPETQEA 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Liver and Mammary tumor.
[2]"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-514, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Liver.
[3]"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-514; SER-561 AND SER-654, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[4]"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-514 AND SER-526, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic fibroblast.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC024076 mRNA. Translation: AAH24076.1.
BC026864 mRNA. Translation: AAH26864.1.
UniGeneMm.244118.
Mm.438038.

3D structure databases

ProteinModelPortalQ8R311.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ8R311. 4 interactions.
MINTMINT-4092511.

PTM databases

PhosphoSiteQ8R311.

Proteomic databases

MaxQBQ8R311.
PaxDbQ8R311.
PRIDEQ8R311.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1346056. Ctage5.

Phylogenomic databases

eggNOGNOG133684.
HOGENOMHOG000112043.
HOVERGENHBG051216.
InParanoidQ8R311.
PhylomeDBQ8R311.

Gene expression databases

CleanExMM_CTAGE5.
GenevestigatorQ8R311.

Family and domain databases

ProtoNetSearch...

Other

ChiTaRSCTAGE5. mouse.
PROQ8R311.
SOURCESearch...

Entry information

Entry nameCTGE5_MOUSE
AccessionPrimary (citable) accession number: Q8R311
Secondary accession number(s): Q8CIE3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: June 1, 2002
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot