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Protein
Submitted name:

Pdk1 protein

Gene

Pdk1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Pdk1 proteinImported
Gene namesi
Name:Pdk1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1926119. Pdk1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: MGI
  • plasma membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8R2U8.
ExpressionAtlasiQ8R2U8. baseline and differential.
GenevestigatoriQ8R2U8.

Structurei

3D structure databases

ProteinModelPortaliQ8R2U8.
SMRiQ8R2U8. Positions 39-419.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG000511.

Family and domain databases

Gene3Di1.20.140.20. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR018955. BCDHK/PDK_N.
IPR003594. HATPase_C.
IPR005467. Sig_transdc_His_kinase_core.
[Graphical view]
PfamiPF10436. BCDHK_Adom3. 1 hit.
PF02518. HATPase_c. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
SSF69012. SSF69012. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R2U8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLARLLRGG TSVRPLCAVP CASRSLASAS GSGPASELGV PGQVDFYARF
60 70 80 90 100
SPSPLSMKQF LDFGSVNACE KTSFMFLRQE LPVRLANIMK EISLLPDNLL
110 120 130 140 150
RTPSVQLVQS WYIQSLQELL DFKDKSAEDA KTIYEFTDTV IRIRNRHNDV
160 170 180 190 200
IPTMAQGVTE YKESFGVDPV TSQNVQYFLD RFYMSRISIR MLLNQHSLLF
210 220 230 240 250
GGKGSPSHRK HIGSINPNCD VVEVIKDGYE NARRLCDLYY VNSPELELEE
260 270 280 290 300
LNAKSPGQTI QVVYVPSHLY HMVFELFKNA MRATMEHHAD KGVYPPIQVH
310 320 330 340 350
VTLGEEDLTV KMSDRGGGVP LRKIDRLFNY MYSTAPRPRV ETSRAVPLAG
360 370 380 390 400
FGYGLPISRL YAQYFQGDLK LYSLEGYGTD AVIYIKALST ESVERLPVYN
410 420 430
KAAWKHYKAN HEADDWCVPS REPKDMTTFR SS
Length:432
Mass (Da):48,837
Last modified:June 1, 2002 - v1
Checksum:i6682B5DEE68E62AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC027196 mRNA. Translation: AAH27196.1.
UniGeneiMm.34411.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC027196 mRNA. Translation: AAH27196.1.
UniGeneiMm.34411.

3D structure databases

ProteinModelPortaliQ8R2U8.
SMRiQ8R2U8. Positions 39-419.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1926119. Pdk1.

Phylogenomic databases

HOVERGENiHBG000511.

Miscellaneous databases

ChiTaRSiPdk1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ8R2U8.
ExpressionAtlasiQ8R2U8. baseline and differential.
GenevestigatoriQ8R2U8.

Family and domain databases

Gene3Di1.20.140.20. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR018955. BCDHK/PDK_N.
IPR003594. HATPase_C.
IPR005467. Sig_transdc_His_kinase_core.
[Graphical view]
PfamiPF10436. BCDHK_Adom3. 1 hit.
PF02518. HATPase_c. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
SSF69012. SSF69012. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.

Entry informationi

Entry nameiQ8R2U8_MOUSE
AccessioniPrimary (citable) accession number: Q8R2U8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: May 27, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.