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Protein

snRNA-activating protein complex subunit 5

Gene

Snapc5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
snRNA-activating protein complex subunit 5
Short name:
SNAPc subunit 5
Alternative name(s):
Small nuclear RNA-activating complex polypeptide 5
snRNA-activating protein complex 19 kDa subunit
Short name:
SNAPc 19 kDa subunit
Gene namesi
Name:Snapc5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1914282. Snapc5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000720291 – 98snRNA-activating protein complex subunit 5Add BLAST98

Proteomic databases

PaxDbiQ8R2K7.
PRIDEiQ8R2K7.

PTM databases

PhosphoSitePlusiQ8R2K7.

Interactioni

Subunit structurei

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4 (By similarity).By similarity

Protein-protein interaction databases

BioGridi237056. 2 interactors.
STRINGi10090.ENSMUSP00000034965.

Structurei

3D structure databases

ProteinModelPortaliQ8R2K7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi86 – 95Poly-Glu10

Phylogenomic databases

eggNOGiENOG410J33C. Eukaryota.
ENOG4112ANI. LUCA.
HOGENOMiHOG000013144.
HOVERGENiHBG055993.
InParanoidiQ8R2K7.
KOiK15211.
PhylomeDBiQ8R2K7.

Family and domain databases

InterProiIPR029138. SNAPC5.
[Graphical view]
PfamiPF15497. SNAPc19. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8R2K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRLQELRK EEETLLRLKA ALHDQLNRLK VEELALQSMI NSRGRTETLS
60 70 80 90
SQPAPEQLCD MSLHVDNEVT INQTTLKLST RSPMEEEEEE EEEEESDS
Length:98
Mass (Da):11,340
Last modified:June 1, 2002 - v1
Checksum:iB33117DFA0A2FCE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028529 mRNA. Translation: AAH28529.1.
RefSeqiNP_899139.2. NM_183316.2.
UniGeneiMm.24082.

Genome annotation databases

GeneIDi330959.
KEGGimmu:330959.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028529 mRNA. Translation: AAH28529.1.
RefSeqiNP_899139.2. NM_183316.2.
UniGeneiMm.24082.

3D structure databases

ProteinModelPortaliQ8R2K7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi237056. 2 interactors.
STRINGi10090.ENSMUSP00000034965.

PTM databases

PhosphoSitePlusiQ8R2K7.

Proteomic databases

PaxDbiQ8R2K7.
PRIDEiQ8R2K7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi330959.
KEGGimmu:330959.

Organism-specific databases

CTDi10302.
MGIiMGI:1914282. Snapc5.

Phylogenomic databases

eggNOGiENOG410J33C. Eukaryota.
ENOG4112ANI. LUCA.
HOGENOMiHOG000013144.
HOVERGENiHBG055993.
InParanoidiQ8R2K7.
KOiK15211.
PhylomeDBiQ8R2K7.

Miscellaneous databases

ChiTaRSiSnapc5. mouse.
PROiQ8R2K7.
SOURCEiSearch...

Family and domain databases

InterProiIPR029138. SNAPC5.
[Graphical view]
PfamiPF15497. SNAPc19. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSNPC5_MOUSE
AccessioniPrimary (citable) accession number: Q8R2K7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: June 1, 2002
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.