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Protein

snRNA-activating protein complex subunit 5

Gene

Snapc5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
snRNA-activating protein complex subunit 5
Short name:
SNAPc subunit 5
Alternative name(s):
Small nuclear RNA-activating complex polypeptide 5
snRNA-activating protein complex 19 kDa subunit
Short name:
SNAPc 19 kDa subunit
Gene namesi
Name:Snapc5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1914282. Snapc5.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000720291 – 98snRNA-activating protein complex subunit 5Add BLAST98

Proteomic databases

PaxDbiQ8R2K7.
PRIDEiQ8R2K7.

PTM databases

PhosphoSitePlusiQ8R2K7.

Interactioni

Subunit structurei

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4 (By similarity).By similarity

Protein-protein interaction databases

BioGridi237056. 2 interactors.
STRINGi10090.ENSMUSP00000034965.

Structurei

3D structure databases

ProteinModelPortaliQ8R2K7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi86 – 95Poly-Glu10

Phylogenomic databases

eggNOGiENOG410J33C. Eukaryota.
ENOG4112ANI. LUCA.
HOGENOMiHOG000013144.
HOVERGENiHBG055993.
InParanoidiQ8R2K7.
KOiK15211.
PhylomeDBiQ8R2K7.

Family and domain databases

InterProiView protein in InterPro
IPR029138. SNAPC5.
PfamiView protein in Pfam
PF15497. SNAPc19. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8R2K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRLQELRK EEETLLRLKA ALHDQLNRLK VEELALQSMI NSRGRTETLS
60 70 80 90
SQPAPEQLCD MSLHVDNEVT INQTTLKLST RSPMEEEEEE EEEEESDS
Length:98
Mass (Da):11,340
Last modified:June 1, 2002 - v1
Checksum:iB33117DFA0A2FCE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028529 mRNA. Translation: AAH28529.1.
RefSeqiNP_899139.2. NM_183316.2.
UniGeneiMm.24082.

Genome annotation databases

GeneIDi330959.
KEGGimmu:330959.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028529 mRNA. Translation: AAH28529.1.
RefSeqiNP_899139.2. NM_183316.2.
UniGeneiMm.24082.

3D structure databases

ProteinModelPortaliQ8R2K7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi237056. 2 interactors.
STRINGi10090.ENSMUSP00000034965.

PTM databases

PhosphoSitePlusiQ8R2K7.

Proteomic databases

PaxDbiQ8R2K7.
PRIDEiQ8R2K7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi330959.
KEGGimmu:330959.

Organism-specific databases

CTDi10302.
MGIiMGI:1914282. Snapc5.

Phylogenomic databases

eggNOGiENOG410J33C. Eukaryota.
ENOG4112ANI. LUCA.
HOGENOMiHOG000013144.
HOVERGENiHBG055993.
InParanoidiQ8R2K7.
KOiK15211.
PhylomeDBiQ8R2K7.

Miscellaneous databases

ChiTaRSiSnapc5. mouse.
PROiQ8R2K7.
SOURCEiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR029138. SNAPC5.
PfamiView protein in Pfam
PF15497. SNAPc19. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSNPC5_MOUSE
AccessioniPrimary (citable) accession number: Q8R2K7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: June 1, 2002
Last modified: March 15, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.