Voltage-gated calcium channel alpha-1D subunit - Rattus norvegicus (Rat)

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Unreviewed, UniProtKB/TrEMBL Q8R2F3 (Q8R2F3_RAT)

Last modified January 19, 2010. Version 46. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Voltage-gated calcium channel alpha-1D subunit EMBL AAL89642.1

Gene names

Name:

Cacna1d RGD 70973

Organism

Rattus norvegicus (Rat) EMBL AAL89642.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	236 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU003808V0.
Sequence similarities	Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]

Ontologies

Keywords
Biological process	Calcium transport Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378V0
Ligand	Calcium
Molecular function	Calcium channel RuleBase RU003808V0 Ionic channel Voltage-gated channel RuleBase RU003808V0
Gene Ontology (GO)
Biological process	calcium ion transport Inferred from electronic annotation. Source: UniProtKB-KW calcium-mediated signaling Inferred from direct assay. Source: RGD memory Inferred from expression pattern. Source: RGD transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	apical plasma membrane Inferred from direct assay. Source: RGD voltage-gated calcium channel complex Traceable author statement. Source: RGD
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW voltage-gated calcium channel activity Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAL89642.1

Non-terminal residue

1

EMBL AAL89642.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q8R2F3-1 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 9520F30DA7C9F524
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236

27,546

        10         20         30         40         50         60 
EYALKARPLR RYIPKNPYQY KFWYVVNSSP FEYMMFVLIM LNTLCLAMQH YEQSKMFNDA 

        70         80         90        100        110        120 
MDILNMVFTG VFTVEMVLKV IAFKPKHYFT DAWNTFDALI VVGSVVDIAI TEVNNSEESN 

       130        140        150        160        170        180 
RISITFFRLF RVMRLVKLLS RGEGIRTLLW TFIKSFQALP YVALLIAMLF FIYAVIGMQM 

       190        200        210        220        230 
FGKVAMRDNN QINRNNNFQT FPQAVLLLFR CATGEAWQEI MLACLPGKLC DPDSDY

References

[1]

"Voltage-gated Ca2+ channel Ca(V)1.3 subunit expressed in the hair cell epithelium of the sacculus of the trout Oncorhynchus mykiss: cloning and comparison across vertebrate classes."
Ramakrishnan N.A., Green G.E., Pasha R., Drescher M.J., Swanson G.S., Perin P.C., Lakhani R.S., Ahsan S.F., Hatfield J.S., Khan K.M., Drescher D.G.
Brain Res. Mol. Brain Res. 109:69-83(2002) [PubMed: 12531517] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Organ of Corti EMBL AAL89642.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF422932 mRNA. Translation: AAL89642.1.
IPI	IPI00568196.
UniGene	Rn.89671
3D structure databases
SMR	Q8R2F3. Positions 23-221.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8R2F3.
Genome annotation databases
Ensembl	ENSRNOT00000046889; ENSRNOP00000043131; ENSRNOG00000013147; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	Q8R2F3.
Gene expression databases
ArrayExpress	Q8R2F3.
Genevestigator	Q8R2F3.
Family and domain databases
InterPro	IPR005821. Ion_trans. IPR002077. VDCCAlpha1. [Graphical view]
Pfam	PF00520. Ion_trans. 1 hit. [Graphical view]
PRINTS	PR00167. CACHANNEL.
ProtoNet	Search...

Entry information

Entry name

Q8R2F3_RAT

Accession

Primary (citable) accession number: Q8R2F3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 19, 2010
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information