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Protein
Submitted name:

Efemp1 protein

Gene

Efemp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. epidermal growth factor-activated receptor activity Source: MGI
  3. epidermal growth factor receptor binding Source: MGI

GO - Biological processi

  1. epidermal growth factor receptor signaling pathway Source: MGI
  2. negative regulation of chondrocyte differentiation Source: MGI
  3. peptidyl-tyrosine phosphorylation Source: MGI
  4. regulation of transcription, DNA-templated Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Efemp1 proteinImported
Gene namesi
Name:Efemp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339998. Efemp1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: Ensembl
  2. extracellular space Source: MGI
  3. extracellular vesicular exosome Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8R1U8.

Expressioni

Gene expression databases

BgeeiQ8R1U8.
ExpressionAtlasiQ8R1U8. baseline and differential.
GenevestigatoriQ8R1U8.

Structurei

3D structure databases

ProteinModelPortaliQ8R1U8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG051560.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
[Graphical view]
PfamiPF07645. EGF_CA. 1 hit.
[Graphical view]
PROSITEiPS01186. EGF_2. 1 hit.
PS01187. EGF_CA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8R1U8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QYQCVNEPGK FSCMCPQGYE VVRSRTCQDI NECETTNECR EDEMCWNYHG
60 70 80 90 100
GFRCYPRNPC QDHYVLTSEN RCVCPVSNTM CRELPQSIVY KYMSIRSDRS
110 120 130 140 150
VPSDIFQIQA TMIYANTINT FRIKSGNENG EFYLRQTSPV SAMLVLVKSL
160 170 180
SGPREYIVDL EMLTVSSIGT FRTSSVLRLT IIVGPFSF
Length:188
Mass (Da):21,564
Last modified:May 31, 2002 - v1
Checksum:i427A790838F116CB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023060 mRNA. Translation: AAH23060.1.
UniGeneiMm.44176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023060 mRNA. Translation: AAH23060.1.
UniGeneiMm.44176.

3D structure databases

ProteinModelPortaliQ8R1U8.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ8R1U8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1339998. Efemp1.

Phylogenomic databases

HOVERGENiHBG051560.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ8R1U8.
ExpressionAtlasiQ8R1U8. baseline and differential.
GenevestigatoriQ8R1U8.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR018097. EGF_Ca-bd_CS.
[Graphical view]
PfamiPF07645. EGF_CA. 1 hit.
[Graphical view]
PROSITEiPS01186. EGF_2. 1 hit.
PS01187. EGF_CA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.

Entry informationi

Entry nameiQ8R1U8_MOUSE
AccessioniPrimary (citable) accession number: Q8R1U8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2002
Last sequence update: May 31, 2002
Last modified: February 3, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.