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Protein

Cytochrome b-c1 complex subunit 9

Gene

Uqcr10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit interacts with cytochrome c1 (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105. Respiratory electron transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b-c1 complex subunit 9
Alternative name(s):
Complex III subunit 9
Complex III subunit X
Cytochrome c1 non-heme 7 kDa protein
Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
Gene namesi
Name:Uqcr10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1913402. Uqcr10.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001935541 – 64Cytochrome b-c1 complex subunit 9Add BLAST64

Proteomic databases

EPDiQ8R1I1.
MaxQBiQ8R1I1.
PaxDbiQ8R1I1.
PRIDEiQ8R1I1.

PTM databases

iPTMnetiQ8R1I1.
PhosphoSitePlusiQ8R1I1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000059534.
CleanExiMM_1110020P15RIK.
ExpressionAtlasiQ8R1I1. baseline and differential.
GenevisibleiQ8R1I1. MM.

Interactioni

Subunit structurei

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).By similarity

Protein-protein interaction databases

BioGridi211253. 2 interactors.
CORUMiQ8R1I1.
IntActiQ8R1I1. 2 interactors.
STRINGi10090.ENSMUSP00000054856.

Structurei

3D structure databases

ProteinModelPortaliQ8R1I1.
SMRiQ8R1I1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UQCR10/QCR9 family.Curated

Phylogenomic databases

eggNOGiKOG3494. Eukaryota.
ENOG410XUZE. LUCA.
GeneTreeiENSGT00390000014052.
HOGENOMiHOG000215187.
HOVERGENiHBG056661.
InParanoidiQ8R1I1.
KOiK00419.
OMAiKQWKDIR.
OrthoDBiEOG091G18MS.
PhylomeDBiQ8R1I1.
TreeFamiTF324385.

Family and domain databases

Gene3Di1.20.5.260. 1 hit.
InterProiView protein in InterPro
IPR008027. QCR9.
IPR036656. QCR9_sf.
PANTHERiPTHR12980. PTHR12980. 1 hit.
PfamiView protein in Pfam
PF05365. UCR_UQCRX_QCR9. 1 hit.
SUPFAMiSSF81514. SSF81514. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8R1I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPTIPSRL YSLLFRRTST FALTIAVGAL FFERAFDQGA DAIYEHINEG
60
KLWKHIKHKY ENKE
Length:64
Mass (Da):7,446
Last modified:June 1, 2002 - v1
Checksum:i54DECD7452434CAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC024518 mRNA. Translation: AAH24518.1.
CCDSiCCDS36098.1.
RefSeqiNP_932096.1. NM_197979.2.
UniGeneiMm.269736.

Genome annotation databases

EnsembliENSMUST00000058407; ENSMUSP00000054856; ENSMUSG00000059534.
GeneIDi66152.
KEGGimmu:66152.
UCSCiuc007hvb.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQCR9_MOUSE
AccessioniPrimary (citable) accession number: Q8R1I1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: June 1, 2002
Last modified: October 25, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families