Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8R154

- Q8R154_MOUSE

UniProt

Q8R154 - Q8R154_MOUSE

Protein
Submitted name:

Trim24 protein

Gene

Trim24

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. chromatin binding Source: MGI
    2. ligand-dependent nuclear receptor binding Source: MGI
    3. protein binding Source: MGI
    4. protein kinase activity Source: MGI
    5. sequence-specific DNA binding Source: MGI
    6. zinc ion binding Source: InterPro

    GO - Biological processi

    1. calcium ion homeostasis Source: MGI
    2. negative regulation of cell proliferation Source: MGI
    3. negative regulation of transcription, DNA-templated Source: MGI
    4. positive regulation of gene expression Source: MGI
    5. positive regulation of transcription, DNA-templated Source: MGI
    6. protein autophosphorylation Source: MGI
    7. protein phosphorylation Source: MGI
    8. regulation of signal transduction by p53 class mediator Source: MGI
    9. regulation of vitamin D receptor signaling pathway Source: MGI

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Trim24 proteinImported
    Gene namesi
    Name:Trim24Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:109275. Trim24.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. nuclear euchromatin Source: MGI
    3. nucleus Source: MGI
    4. perichromatin fibrils Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ8R154.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000031859.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8R154.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Zinc-fingerSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000252971.
    HOVERGENiHBG054599.
    InParanoidiQ8R154.

    Family and domain databases

    Gene3Di1.20.920.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProiIPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF00439. Bromodomain. 1 hit.
    PF00628. PHD. 1 hit.
    [Graphical view]
    PRINTSiPR00503. BROMODOMAIN.
    SMARTiSM00297. BROMO. 1 hit.
    SM00249. PHD. 1 hit.
    [Graphical view]
    SUPFAMiSSF47370. SSF47370. 1 hit.
    SSF57903. SSF57903. 1 hit.
    PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    PS50016. ZF_PHD_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8R154-1 [UniParc]FASTAAdd to Basket

    « Hide

    PRVRGRVGQN VPRQTTIKPN PLQMAFLAQQ AIKQWQISSV QAPPTTASSS    50
    SSTPSSPTIT SAAGYDGKAF SSPMIDLSAP VGGSYNLPSL PDIDCSSTIM 100
    LDNIARKDTG VDHAQPRPPS NRTVQSPNSS VPSPGLAGPV TMTSVHPPIR 150
    SPSASSVGSR GSSGSSSKPA GADSTHKVPV VMLEPIRIKQ ENSGPPENYD 200
    FPVVIVKQES DEESRPQNTN YPRSILTSLL LNSSQSSASE ETVLRSDAPD 250
    STGDQPGLHQ ENSSNGKSEW SDASQKSPVH VGETRKEDDP NEDWCAVCQN 300
    GGELLCCEKC PKVFHLTCHV PTLTNFPSGE WICTFCRDLS KPEVDYDCDV 350
    PSHHSEKRKS EGLTKLTPID KRKCERLLLF LYCHEMSLAF QDPVPLTVPD 400
    YYKIIKNPMD LSTIKKRLQE DYCMYTKPED FVADFRLIFQ NCAEFNEPDS 450
    EVANAGIKLE SYFEELLKNL YPEKRFPKVE FRHEAEDCKF SDDSDDDFVQ 500
    PRKKRLKSTE DRQLLK 516
    Length:516
    Mass (Da):57,114
    Last modified:June 1, 2002 - v1
    Checksum:i3B20FB95ED64F299
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC025482 mRNA. Translation: AAH25482.1.
    UniGeneiMm.41063.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC025482 mRNA. Translation: AAH25482.1 .
    UniGenei Mm.41063.

    3D structure databases

    ProteinModelPortali Q8R154.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000031859.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:109275. Trim24.

    Phylogenomic databases

    HOGENOMi HOG000252971.
    HOVERGENi HBG054599.
    InParanoidi Q8R154.

    Miscellaneous databases

    ChiTaRSi TRIM24. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8R154.

    Family and domain databases

    Gene3Di 1.20.920.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProi IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF00439. Bromodomain. 1 hit.
    PF00628. PHD. 1 hit.
    [Graphical view ]
    PRINTSi PR00503. BROMODOMAIN.
    SMARTi SM00297. BROMO. 1 hit.
    SM00249. PHD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47370. SSF47370. 1 hit.
    SSF57903. SSF57903. 1 hit.
    PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    PS50016. ZF_PHD_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Mix FVB/NImported.
      Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.

    Entry informationi

    Entry nameiQ8R154_MOUSE
    AccessioniPrimary (citable) accession number: Q8R154
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)