SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8R154

- Q8R154_MOUSE

UniProt

Q8R154 - Q8R154_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Trim24 protein
Gene
Trim24
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. ligand-dependent nuclear receptor binding Source: MGI
  3. protein binding Source: MGI
  4. protein kinase activity Source: MGI
  5. sequence-specific DNA binding Source: MGI
  6. zinc ion binding Source: InterPro

GO - Biological processi

  1. calcium ion homeostasis Source: MGI
  2. negative regulation of cell proliferation Source: MGI
  3. negative regulation of transcription, DNA-templated Source: MGI
  4. positive regulation of gene expression Source: MGI
  5. positive regulation of transcription, DNA-templated Source: MGI
  6. protein autophosphorylation Source: MGI
  7. protein phosphorylation Source: MGI
  8. regulation of signal transduction by p53 class mediator Source: MGI
  9. regulation of vitamin D receptor signaling pathway Source: MGI
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Trim24 proteinImported
Gene namesi
Name:Trim24Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109275. Trim24.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. nuclear euchromatin Source: MGI
  3. nucleus Source: MGI
  4. perichromatin fibrils Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8R154.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031859.

Structurei

3D structure databases

ProteinModelPortaliQ8R154.

Family & Domainsi

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

HOGENOMiHOG000252971.
HOVERGENiHBG054599.
InParanoidiQ8R154.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
PF00628. PHD. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8R154-1 [UniParc]FASTAAdd to Basket

« Hide

PRVRGRVGQN VPRQTTIKPN PLQMAFLAQQ AIKQWQISSV QAPPTTASSS    50
SSTPSSPTIT SAAGYDGKAF SSPMIDLSAP VGGSYNLPSL PDIDCSSTIM 100
LDNIARKDTG VDHAQPRPPS NRTVQSPNSS VPSPGLAGPV TMTSVHPPIR 150
SPSASSVGSR GSSGSSSKPA GADSTHKVPV VMLEPIRIKQ ENSGPPENYD 200
FPVVIVKQES DEESRPQNTN YPRSILTSLL LNSSQSSASE ETVLRSDAPD 250
STGDQPGLHQ ENSSNGKSEW SDASQKSPVH VGETRKEDDP NEDWCAVCQN 300
GGELLCCEKC PKVFHLTCHV PTLTNFPSGE WICTFCRDLS KPEVDYDCDV 350
PSHHSEKRKS EGLTKLTPID KRKCERLLLF LYCHEMSLAF QDPVPLTVPD 400
YYKIIKNPMD LSTIKKRLQE DYCMYTKPED FVADFRLIFQ NCAEFNEPDS 450
EVANAGIKLE SYFEELLKNL YPEKRFPKVE FRHEAEDCKF SDDSDDDFVQ 500
PRKKRLKSTE DRQLLK 516
Length:516
Mass (Da):57,114
Last modified:June 1, 2002 - v1
Checksum:i3B20FB95ED64F299
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC025482 mRNA. Translation: AAH25482.1.
UniGeneiMm.41063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC025482 mRNA. Translation: AAH25482.1 .
UniGenei Mm.41063.

3D structure databases

ProteinModelPortali Q8R154.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000031859.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:109275. Trim24.

Phylogenomic databases

HOGENOMi HOG000252971.
HOVERGENi HBG054599.
InParanoidi Q8R154.

Miscellaneous databases

ChiTaRSi TRIM24. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8R154.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProi IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF00439. Bromodomain. 1 hit.
PF00628. PHD. 1 hit.
[Graphical view ]
PRINTSi PR00503. BROMODOMAIN.
SMARTi SM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Mix FVB/NImported.
    Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.

Entry informationi

Entry nameiQ8R154_MOUSE
AccessioniPrimary (citable) accession number: Q8R154
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi