Q8R149 (BUD13_MOUSE) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 29, 2013.
Version 75.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: BUD13 homolog | ||
| Gene names |
| ||
| Organism | Mus musculus (Mouse) [Reference proteome] | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus |
Protein attributes
| Sequence length | 637 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Sequence similarities | Belongs to the CWC26 family. |
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Alternative splicing |
| Domain | Coiled coil |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| None. [Check GOA] | |
Alternative products
| This entry describes 2 isoforms produced by alternative splicing. [Align] [Select] | ||||||
| Isoform 1 (identifier: Q8R149-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. | ||||||
| Isoform 2 (identifier: Q8R149-2) The sequence of this isoform differs from the canonical sequence as follows: 608-637: Missing. | ||||||
| Note: No experimental confirmation available. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 637 | 637 | BUD13 homolog | PRO_0000287689 | |||||
Regions | |||||||||
| Coiled coil | 490 – 538 | 49 | Potential | ||||||
| Compositional bias | 123 – 228 | 106 | Pro-rich | ||||||
Amino acid modifications | |||||||||
| Modified residue | 157 | 1 | Phosphothreonine Ref.4 | ||||||
| Modified residue | 170 | 1 | Phosphothreonine Ref.4 | ||||||
| Modified residue | 174 | 1 | Phosphoserine Ref.4 | ||||||
| Modified residue | 209 | 1 | Phosphothreonine Ref.4 | ||||||
| Modified residue | 213 | 1 | Phosphoserine Ref.4 | ||||||
| Modified residue | 222 | 1 | Phosphothreonine Ref.4 | ||||||
| Modified residue | 226 | 1 | Phosphoserine Ref.4 | ||||||
| Modified residue | 238 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 259 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 264 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 272 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 297 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 341 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 344 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 371 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 373 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 376 | 1 | Phosphoserine Ref.3 | ||||||
| Modified residue | 512 | 1 | Phosphotyrosine By similarity | ||||||
Natural variations | |||||||||
| Alternative sequence | 608 – 637 | 30 | Missing in isoform 2. | VSP_025591 | |||||
Experimental info | |||||||||
| Sequence conflict | 174 | 1 | S → Y in BAC34509. Ref.1 | ||||||
| Sequence conflict | 189 | 1 | P → H in BAC34509. Ref.1 | ||||||
Sequences
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References
| [1] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.  Hayashizaki Y.Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2). Strain: C57BL/6J. Tissue: Thymus and Vagina. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: FVB/N. Tissue: Mammary tumor. |
| [3] | "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341; SER-344; SER-371; SER-373 AND SER-376, MASS SPECTROMETRY. Tissue: Liver. |
| [4] | "Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-157; THR-170; SER-174; THR-209; SER-213; THR-222 AND SER-226, MASS SPECTROMETRY. Tissue: Melanoma. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AK037134 mRNA. Translation: BAC29716.1. AK038126 mRNA. Translation: BAE20531.1. AK051047 mRNA. Translation: BAC34509.1. BC025490 mRNA. Translation: AAH25490.1. |
| IPI | IPI00153284. IPI00845543. |
| RefSeq | NP_666112.1. NM_146000.2. |
| UniGene | Mm.32648. |
3D structure databases | |
| ProteinModelPortal | Q8R149. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q8R149. 11 interactions. |
| MINT | MINT-4118536. |
PTM databases | |
| PhosphoSite | Q8R149. |
Proteomic databases | |
| PaxDb | Q8R149. |
| PRIDE | Q8R149. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUST00000074957; ENSMUSP00000074490; ENSMUSG00000032077. |
| GeneID | 215051. |
| KEGG | mmu:215051. |
| UCSC | uc009phi.1. mouse. |
Organism-specific databases | |
| CTD | 84811. |
| MGI | MGI:2443443. Bud13. |
Phylogenomic databases | |
| eggNOG | NOG317350. |
| GeneTree | ENSGT00390000014500. |
| HOGENOM | HOG000273883. |
| HOVERGEN | HBG059757. |
| InParanoid | Q8R149. |
| KO | K13106. |
| OMA | SPRRVRH. |
| OrthoDB | EOG40ZQZ9. |
Gene expression databases | |
| Bgee | Q8R149. |
| CleanEx | MM_BUD13. |
| Genevestigator | Q8R149. |
Family and domain databases | |
| InterPro | IPR018609. Bud13. [Graphical view] |
| Pfam | PF09736. Bud13. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 374592. |
| SOURCE | Search... |
Entry information
| Entry name | BUD13_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q8R149 Secondary accession number(s): Q8BQC0, Q8CB03 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |