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Q8R0W0

- EPIPL_MOUSE

UniProt

Q8R0W0 - EPIPL_MOUSE

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Protein
Epiplakin
Gene
Eppk1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Epiplakin
Gene namesi
Name:Eppk1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:2386306. Eppk1.

Subcellular locationi

Cytoplasmcytoskeleton By similarity

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. cytoskeleton Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 65486548Epiplakin
PRO_0000078146Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1537 – 15371Phosphoserine1 Publication
Modified residuei2430 – 24301Phosphoserine By similarity
Modified residuei2508 – 25081Phosphoserine By similarity
Modified residuei2606 – 26061Phosphoserine1 Publication
Modified residuei2705 – 27051Phosphoserine1 Publication
Modified residuei2707 – 27071Phosphoserine By similarity
Modified residuei2945 – 29451Phosphoserine By similarity
Modified residuei3023 – 30231Phosphoserine By similarity
Modified residuei3121 – 31211Phosphoserine1 Publication
Modified residuei3220 – 32201Phosphoserine1 Publication
Modified residuei3636 – 36361Phosphoserine1 Publication
Modified residuei3735 – 37351Phosphoserine1 Publication
Modified residuei3737 – 37371Phosphoserine By similarity
Modified residuei3975 – 39751Phosphoserine By similarity
Modified residuei4053 – 40531Phosphoserine By similarity
Modified residuei4151 – 41511Phosphoserine1 Publication
Modified residuei4250 – 42501Phosphoserine1 Publication
Modified residuei4252 – 42521Phosphoserine By similarity
Modified residuei4490 – 44901Phosphoserine By similarity
Modified residuei4568 – 45681Phosphoserine By similarity
Modified residuei4666 – 46661Phosphoserine1 Publication
Modified residuei4765 – 47651Phosphoserine1 Publication
Modified residuei5181 – 51811Phosphoserine1 Publication
Modified residuei5280 – 52801Phosphoserine1 Publication
Modified residuei5282 – 52821Phosphoserine By similarity
Modified residuei5520 – 55201Phosphoserine By similarity
Modified residuei5598 – 55981Phosphoserine By similarity
Modified residuei5696 – 56961Phosphoserine1 Publication
Modified residuei5795 – 57951Phosphoserine1 Publication
Modified residuei6211 – 62111Phosphoserine1 Publication
Modified residuei6310 – 63101Phosphoserine1 Publication
Modified residuei6312 – 63121Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8R0W0.
PRIDEiQ8R0W0.

PTM databases

PhosphoSiteiQ8R0W0.

Expressioni

Tissue specificityi

High levels in skin, small intestine and salivary gland. Lower levels in lung, uterus and liver. Not detected in brain, kidney, muscle, heart or spleen. In skin, expressed in all epidermal layers but not in the dermis. In intestine, expressed exclusively in the epithelial cell layer of the villi. In liver, expressed at hepatocyte margins.1 Publication

Gene expression databases

CleanExiMM_EPPK1.
GenevestigatoriQ8R0W0.

Interactioni

Protein-protein interaction databases

BioGridi230168. 1 interaction.
IntActiQ8R0W0. 1 interaction.
MINTiMINT-1866986.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati41 – 7838Plectin 1
Add
BLAST
Repeati79 – 11638Plectin 2
Add
BLAST
Repeati117 – 15438Plectin 3
Add
BLAST
Repeati155 – 19238Plectin 4
Add
BLAST
Repeati285 – 32238Plectin 5
Add
BLAST
Repeati323 – 36038Plectin 6
Add
BLAST
Repeati362 – 39837Plectin 7
Add
BLAST
Repeati399 – 43638Plectin 8
Add
BLAST
Repeati437 – 47034Plectin 9
Add
BLAST
Repeati611 – 64838Plectin 10
Add
BLAST
Repeati649 – 68638Plectin 11
Add
BLAST
Repeati687 – 72438Plectin 12
Add
BLAST
Repeati725 – 76238Plectin 13
Add
BLAST
Repeati766 – 80035Plectin 14
Add
BLAST
Repeati931 – 96838Plectin 15
Add
BLAST
Repeati969 – 100638Plectin 16
Add
BLAST
Repeati1007 – 104438Plectin 17
Add
BLAST
Repeati1224 – 128461Plectin 18
Add
BLAST
Repeati1285 – 132238Plectin 19
Add
BLAST
Repeati1323 – 136038Plectin 20
Add
BLAST
Repeati1361 – 139838Plectin 21
Add
BLAST
Repeati1402 – 143635Plectin 22
Add
BLAST
Repeati1572 – 160938Plectin 23
Add
BLAST
Repeati1610 – 164738Plectin 24
Add
BLAST
Repeati1648 – 168538Plectin 25
Add
BLAST
Repeati1686 – 172338Plectin 26
Add
BLAST
Repeati1727 – 176135Plectin 27
Add
BLAST
Repeati1898 – 193538Plectin 28
Add
BLAST
Repeati1936 – 197338Plectin 29
Add
BLAST
Repeati1974 – 201138Plectin 30
Add
BLAST
Repeati2012 – 204938Plectin 31
Add
BLAST
Repeati2225 – 226743Plectin 32
Add
BLAST
Repeati2268 – 230538Plectin 33
Add
BLAST
Repeati2306 – 234338Plectin 34
Add
BLAST
Repeati2344 – 238138Plectin 35
Add
BLAST
Repeati2385 – 241935Plectin 36
Add
BLAST
Repeati2740 – 278243Plectin 37
Add
BLAST
Repeati2783 – 282038Plectin 38
Add
BLAST
Repeati2821 – 285838Plectin 39
Add
BLAST
Repeati2859 – 289638Plectin 40
Add
BLAST
Repeati2900 – 293435Plectin 41
Add
BLAST
Repeati3255 – 329743Plectin 42
Add
BLAST
Repeati3298 – 333538Plectin 43
Add
BLAST
Repeati3336 – 337338Plectin 44
Add
BLAST
Repeati3374 – 341138Plectin 45
Add
BLAST
Repeati3415 – 344935Plectin 46
Add
BLAST
Repeati3770 – 381243Plectin 47
Add
BLAST
Repeati3813 – 385038Plectin 48
Add
BLAST
Repeati3851 – 388838Plectin 49
Add
BLAST
Repeati3889 – 392638Plectin 50
Add
BLAST
Repeati3930 – 396435Plectin 51
Add
BLAST
Repeati4285 – 432743Plectin 52
Add
BLAST
Repeati4328 – 436538Plectin 53
Add
BLAST
Repeati4366 – 440338Plectin 54
Add
BLAST
Repeati4404 – 444138Plectin 55
Add
BLAST
Repeati4445 – 447935Plectin 56
Add
BLAST
Repeati4800 – 484243Plectin 57
Add
BLAST
Repeati4843 – 488038Plectin 58
Add
BLAST
Repeati4881 – 491838Plectin 59
Add
BLAST
Repeati4919 – 495638Plectin 60
Add
BLAST
Repeati4960 – 499435Plectin 61
Add
BLAST
Repeati5315 – 535743Plectin 62
Add
BLAST
Repeati5358 – 539538Plectin 63
Add
BLAST
Repeati5396 – 543338Plectin 64
Add
BLAST
Repeati5434 – 547138Plectin 65
Add
BLAST
Repeati5475 – 550935Plectin 66
Add
BLAST
Repeati5830 – 587243Plectin 67
Add
BLAST
Repeati5873 – 591038Plectin 68
Add
BLAST
Repeati5911 – 594838Plectin 69
Add
BLAST
Repeati5949 – 598638Plectin 70
Add
BLAST
Repeati5990 – 602435Plectin 71
Add
BLAST
Repeati6345 – 638743Plectin 72
Add
BLAST
Repeati6388 – 642538Plectin 73
Add
BLAST
Repeati6426 – 646338Plectin 74
Add
BLAST
Repeati6464 – 650138Plectin 75
Add
BLAST
Repeati6505 – 653935Plectin 76
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili545 – 56521 Reviewed prediction
Add
BLAST
Coiled coili851 – 88636 Reviewed prediction
Add
BLAST
Coiled coili1819 – 185133 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Contains 76 plectin repeats.

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

HOVERGENiHBG051491.

Family and domain databases

Gene3Di3.90.1290.10. 16 hits.
InterProiIPR001101. Plectin_repeat.
[Graphical view]
PfamiPF00681. Plectin. 38 hits.
[Graphical view]
SMARTiSM00250. PLEC. 77 hits.
[Graphical view]
SUPFAMiSSF75399. SSF75399. 16 hits.

Sequencei

Sequence statusi: Complete.

Q8R0W0-1 [UniParc]FASTAAdd to Basket

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MNGQAPPHDV VVANGTEKFI VPKIKKNQLG ASTPSRPQAE AALPTTARSI     50
AGVYVEASGQ TQSIYAAIKQ GLLPTGLGLT LLEAQAATGG LVDLAQGQLL 100
PVSEALRRGL VGLELKEKLL AAERAVTGYP DPYGGEKLSL FQAIKKEVVD 150
RTLGWRLLEA QLATGGLVDP TQGVQVAPEL ACQQGLLDKE TWLSLVESEP 200
SMGTPGFSDP NTLEQLPYSV LLGRCVQDPS SGLPLLPLKT TFHTLAGAAS 250
ASMLLEAGVL NEEMVRDLQE GMLVVSDVGT RPEVRRYLEG TGGLAGVVLL 300
PGGHKKSFFQ ATVEHLVSKG IALQLLEAQA ATRTLVHPTT GQRLWVEEAV 350
KAGLVGPELH EQLLVAEQAV TGYYDPFSSS RIPVFQAMKK GLVDQPLALR 400
LLDAQLATGG LICPARRFRL PLEAALRFGC LDEETRQRLS QAMGFSDPTT 450
HDRLGYEQLL ALSVTDPETG LAFLPLPGMS HANEPQGPTF IDHCTRQALS 500
KATTSISVGR YQGRPVSLWE LLFSESVPVK KRAMLAQRHQ EGALSVEELA 550
AELKNIVEQA AATAKVTFAG LRDTVTPGEL LKAEIINQDL FEQLERGQTS 600
AQDVGSLDSV QRYLQGTGSI AGLLLPDSQE RLSIYEARSK GLLRPGTALI 650
LLEAQAATGF IIDPKENKRY SVEEALRAGV IGPDVYAKLL SAEHAVTGYT 700
DPYSGEQISL FQAMQRDLIV RDHGIRLLEA QIATGGVIDP VHSHRVPVDV 750
AYQRGYFDQI LNSILLDPSD DTKGFFDPNT HENLTYLQLL ERCVHDSETG 800
LHLLPLSSTR PQLVDSSTRQ AFQKLLLSVK YGRFRGQRVS AWELVNSEYF 850
TEDRRRQLLQ RYRQRKITLE QVTQLLEKEM RRWTDITLPA LQGQVTAYQL 900
LEAHIINQEL LDQVLTGTIS PDALLQVGDV HRYLRGSGTV GGVLLKPSNQ 950
RISLYQAMKQ KLLPPSTALA LLEAQAATGT ITDPCSMETL SVDEAVCRGV 1000
VGAEVYGKLK RAEHSITGYR DPFSGKKVSL FRAMKKGLVP VEQATRLLEA 1050
QVSTGGVVDP TTHLHLPMPV AVQRGCIDRE MEAALSRSPE TFPTPDGRGH 1100
TSYAQLLEHC LQDKASGLHL LPLTEDAPNV PTDTQIQETL QASAGTEDGL 1150
SLWDLLTSCH FTEEQRRGYL EDVKVGKISV PQLQNTVRSW VHSAKLLARA 1200
RITVPGPRGE VPATWLRDAG IITQETLEAL AQGMQSPDEV AKQPTVKVCL 1250
WGTGCVAGVL LQPSGTKLSI AQAVRDGLLP TGLGQQLLEA QVASGFLVNP 1300
LTNQRLSVEG AVKAGLVGME QSEHLRQVEK AVTGYSDPFS GGSLSLWQAM 1350
EKGLVTQSEA FPLLQVQLAT GGVVDPVHGV HLPQEVAYKL GLLDEQTSRV 1400
LTATGKENKL FFDPNSREKV TYQQLRELCV LDADTGLWLL PLPQGTVLEV 1450
DDHTAVALRA MKVPINMGRF QGHSVSLWDL LHSEYVGAEK RRELVALCCS 1500
GRAAALRQVI GMLTTLVEAA EKQPSQATFK GLRKQVSAGD LFRSQLITKQ 1550
TLDELNQGKR TVQEVTEMDS VRRSLEGGNF IAGVLIQDTK EKMSIPEALR 1600
RHILRPGTAL VLLEAQAATG FIIDPVENRK LTVEQAFQAG MFGKETYMKL 1650
LSAERAVTGY TDPYTGEQIS LFQAMQRDLI VRDHGIRLLE AQIATGGIID 1700
PVHSHRVPVD VAYQRGYFNE EMNRILSDPS DDTKGFFDPN THENLTYLQL 1750
LERCVEDPET GLYMLEIVKK GETYTYIDEA TRQALTSRTV KMYVGKFAGQ 1800
TVSVWDLLSS QYFTEGRRRK LLREYRAQNI GLENLLEVIT STVEETEKQS 1850
QIFKVPGIHG DVTAAELFNS GILNKKTLDA LRSGDRGFQD LRWLEDVRVY 1900
LEGSNYIAGV IAPLTQKVMS FYEASREELI PAGFAAQMLE AQAATGYLMD 1950
PCTNQRLCVD EAIAAGLVGE DLRERLVNAE MAAKGYKDPA TGETIPLYQA 2000
MERKLVGREE ALRLLEVQVA TGGVIDPRHH HRVPLDTACQ RGCMCDDSLV 2050
LIADQKHMRK RFVDPNTQEK VTYQELQDRC QREEKSGWAL FPVVKDKKDI 2100
EYVDEATKRA LEAEQVEVTV GRYRGQRRSV WELLNSEYVS EEKKMELVRL 2150
YKEDTTRALQ KVVELILQMI ADKERRSRQL WFRGLRTQVT AEELLRSEVI 2200
TKQTLEDLEE GRTTVDQIER KEDVKRYLKG TSCIAGVLVP VQGEPGRQEK 2250
MSIYQAMWKG VLRPGTALVL LEAQAATGFI IDPVNNRRLS VEEAVAAGVV 2300
GGEIQEKLLS AERAVTGYTD PYTGDQISLF QAMQRDLIVR DHGIRLLEAQ 2350
IATGGVIDPV HSHRVPVDVA YQRGYFDEDM NSILADPGDD TKGFFDPNTH 2400
ENLTYLQLLR RCVRDPETGF YMLQLAGKGS SVHHLSEELR RALREARVTP 2450
GTGDFQGQSI SVWELLFYRE VPESLRQDLL RCYQAGGLTV HDVTTTLTSL 2500
LARAKDGSPR GDPQGALGKA TMEVKRGHLR GHEVPVWDIL TSNYVSRDTR 2550
KELLAQFSSG SLTLPMLKRR LTTIIEEAEE TQESKPKPRD ASLKQQDTGA 2600
RGSGTSPDEG DAQDSSESAR QQQEQTLRAT TMQVHRGQFR DQQVSVWKVL 2650
FSSYLSETRR EELLAQHLAG KLGVMELVSL LTQIIEETEE RLSKVSFPGL 2700
RRQVSASELC TSGILDRDTM RELAQGTKTI HEVTEMDSVK RYLGGSSCIA 2750
GVLVPVQGEP GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA ATGFIIDPVN 2800
NRRLSVEEAV AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD QISLFQAMQR 2850
DLIVRDHGIR LLEAQIATGG VIDPVHSHRV PVDVAYQRGY FDEDMNSILA 2900
DPGDDTKGFF DPNTHENLTY LQLLRRCVRD PETGFYMLQL AGKGSSVHHL 2950
SEELRRALRE ARVTPGTGDF QGQSISVWEL LFYREVPESL RQDLLRRYQA 3000
GGLTVHDVTT TLTSLLARAK DGSPRXDPQG ALGKATMEVK RGHLRGHXVP 3050
VWDILTSNYV SRDTRKELLA QFSSGSLTLP MLKRRLTTII EEAEETQESK 3100
PKPRDASLKQ QDTGARGSGT SPDEGDAQDS SESARQQQEQ TLRATTMQVH 3150
RGQFRDQQVS VWKVLFSSYL SETRREELLA QHLAGKLGVM ELVSLLTQII 3200
EETEERLSKV SFPGLRRQVS ASELCTSGIL DRDTMRELAQ GTKTIHEVTE 3250
MDSVKRYLGG SSCIAGVLVP VQGEPGRQEK MSIYQAMWKG VLRPGTALVL 3300
LEAQAATGFI IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS AERAVTGYTD 3350
PYTGDQISLF QAMQRDLIVR DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA 3400
YQRGYFDEDM NSILADPGDD TKGFFDPNTH ENLTYLQLLR RCVRDPETGF 3450
YMLQLAGKGS SVHHLSEELR RALREARVTP GTGDFQGQSI SVWELLFYRE 3500
VPESLRQDLL RRYQAGGLTV HDVTTTLTSL LARAKDGSPR XDPQGALGKA 3550
TMEVKRGHLR GHXVPVWDIL TSNYVSRDTR KELLAQFSSG SLTLPMLKRR 3600
LTTIIEEAEE TQESKPKPRD ASLKQQDTGA RGSGTSPDEG DAQDSSESAR 3650
QQQEQTLRAT TMQVHRGQFR DQQVSVWKVL FSSYLSETRR EELLAQHLAG 3700
KLGVMELVSL LTQIIEETEE RLSKVSFPGL RRQVSASELC TSGILDRDTM 3750
RELAQGTKTI HEVTEMDSVK RYLGGSSCIA GVLVPVQGEP GRQEKMSIYQ 3800
AMWKGVLRPG TALVLLEAQA ATGFIIDPVN NRRLSVEEAV AAGVVGGEIQ 3850
EKLLSAERAV TGYTDPYTGD QISLFQAMQR DLIVRDHGIR LLEAQIATGG 3900
VIDPVHSHRV PVDVAYQRGY FDEDMNSILA DPGDDTKGFF DPNTHENLTY 3950
LQLLRRCVRD PETGFYMLQL AGKGSSVHHL SEELRRALRE ARVTPGTGDF 4000
QGQSISVWEL LFYREVPESL RQDLLRRYQA GGLTVHDVTT TLTSLLARAK 4050
DGSPRXDPQG ALGKATMEVK RGHLRGHXVP VWDILTSNYV SRDTRKELLA 4100
QFSSGSLTLP MLKRRLTTII EEAEETQESK PKPRDASLKQ QDTGARGSGT 4150
SPDEGDAQDS SESARQQQEQ TLRATTMQVH RGQFRDQQVS VWKVLFSSYL 4200
SETRREELLA QHLAGKLGVM ELVSLLTQII EETEERLSKV SFPGLRRQVS 4250
ASELCTSGIL DRDTMRELAQ GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP 4300
VQGEPGRQEK MSIYQAMWKG VLRPGTALVL LEAQAATGFI IDPVNNRRLS 4350
VEEAVAAGVV GGEIQEKLLS AERAVTGYTD PYTGDQISLF QAMQRDLIVR 4400
DHGIRLLEAQ IATGGVIDPV HSHRVPVDVA YQRGYFDEDM NSILADPGDD 4450
TKGFFDPNTH ENLTYLQLLR RCVRDPETGF YMLQLAGKGS SVHHLSEELR 4500
RALREARVTP GTGDFQGQSI SVWELLFYRE VPESLRQDLL RRYQAGGLTV 4550
HDVTTTLTSL LARAKDGSPR XDPQGALGKA TMEVKRGHLR GHXVPVWDIL 4600
TSNYVSRDTR KELLAQFSSG SLTLPMLKRR LTTIIEEAEE TQESKPKPRD 4650
ASLKQQDTGA RGSGTSPDEG DAQDSSESAR QQQEQTLRAT TMQVHRGQFR 4700
DQQVSVWKVL FSSYLSETRR EELLAQHLAG KLGVMELVSL LTQIIEETEE 4750
RLSKVSFPGL RRQVSASELC TSGILDRDTM RELAQGTKTI HEVTEMDSVK 4800
RYLGGSSCIA GVLVPVQGEP GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA 4850
ATGFIIDPVN NRRLSVEEAV AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD 4900
QISLFQAMQR DLIVRDHGIR LLEAQIATGG VIDPVHSHRV PVDVAYQRGY 4950
FDEDMNSILA DPGDDTKGFF DPNTHENLTY LQLLRRCVRD PETGFYMLQL 5000
AGKGSSVHHL SEELRRALRE ARVTPGTGDF QGQSISVWEL LFYREVPESL 5050
RQDLLRRYQA GGLTVHDVTT TLTSLLARAK DGSPRXDPQG ALGKATMEVK 5100
RGHLRGHXVP VWDILTSNYV SRDTRKELLA QFSSGSLTLP MLKRRLTTII 5150
EEAEETQESK PKPRDASLKQ QDTGARGSGT SPDEGDAQDS SESARQQQEQ 5200
TLRATTMQVH RGQFRDQQVS VWKVLFSSYL SETRREELLA QHLAGKLGVM 5250
ELVSLLTQII EETEERLSKV SFPGLRRQVS ASELCTSGIL DRDTMRELAQ 5300
GTKTIHEVTE MDSVKRYLGG SSCIAGVLVP VQGEPGRQEK MSIYQAMWKG 5350
VLRPGTALVL LEAQAATGFI IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS 5400
AERAVTGYTD PYTGDQISLF QAMQRDLIVR DHGIRLLEAQ IATGGVIDPV 5450
HSHRVPVDVA YQRGYFDEDM NSILADPGDD TKGFFDPNTH ENLTYLQLLR 5500
RCVRDPETGF YMLQLAGKGS SVHHLSEELR RALREARVTP GTGDFQGQSI 5550
SVWELLFYRE VPESLRQDLL RRYQAGGLTV HDVTTTLTSL LARAKDGSPR 5600
XDPQGALGKA TMEVKRGHLR GHXVPVWDIL TSNYVSRDTR KELLAQFSSG 5650
SLTLPMLKRR LTTIIEEAEE TQESKPKPRD ASLKQQDTGA RGSGTSPDEG 5700
DAQDSSESAR QQQEQTLRAT TMQVHRGQFR DQQVSVWKVL FSSYLSETRR 5750
EELLAQHLAG KLGVMELVSL LTQIIEETEE RLSKVSFPGL RRQVSASELC 5800
TSGILDRDTM RELAQGTKTI HEVTEMDSVK RYLGGSSCIA GVLVPVQGEP 5850
GRQEKMSIYQ AMWKGVLRPG TALVLLEAQA ATGFIIDPVN NRRLSVEEAV 5900
AAGVVGGEIQ EKLLSAERAV TGYTDPYTGD QISLFQAMQR DLIVRDHGIR 5950
LLEAQIATGG VIDPVHSHRV PVDVAYQRGY FDEDMNSILA DPGDDTKGFF 6000
DPNTHENLTY LQLLRRCVRD PETGFYMLQL AGKGSSVHHL SEELRRALRE 6050
ARVTPGTGDF QGQSISVWEL LFYREVPESL RQDLLRRYQA GGLTVHDVTT 6100
TLTSLLARAK DGSPREDPQG ALGKATMEVK RGHLRGHVVP VWDILTSNYV 6150
SRDTRKELLA QFSSGSLTLP MLKRRLTTII EEAEETQESK PKPRDASLKQ 6200
QDTGARGSGT SPDEGDAQDS SESARQQQEQ TLRATTMQVH RGQFRDQQVS 6250
VWKVLFSSYL SETRREELLA QHLAGKLGVM ELVSLLTQII EETEERLSKV 6300
SFPGLRRQVS ASELCTSGIL DRDTMRELAQ GTKTIHEVTE MDSVKRYLGG 6350
SSCIAGVLVP VQGEPGRQEK MSIYQAMWKG VLRPGTALVL LEAQAATGFI 6400
IDPVNNRRLS VEEAVAAGVV GGEIQEKLLS AERAVTGYTD PYTGDQISLF 6450
QAMQRDLIVK NHGIRLLEAQ IATGGVIDPV HSHRVPVDVA YQRGYFDQEM 6500
NSILADPGDD TKGFFDPNTH ENLTYLQLLQ RATIDPETGL LFLSLSKG 6548
Length:6,548
Mass (Da):724,646
Last modified:August 15, 2003 - v2
Checksum:i9162C07AFCA157B6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY312170 mRNA. Translation: AAP70316.1.
BC026387 mRNA. Translation: AAH26387.1.
RefSeqiNP_659097.2. NM_144848.2.
UniGeneiMm.259929.

Genome annotation databases

GeneIDi223650.
KEGGimmu:223650.
UCSCiuc007wio.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY312170 mRNA. Translation: AAP70316.1 .
BC026387 mRNA. Translation: AAH26387.1 .
RefSeqi NP_659097.2. NM_144848.2.
UniGenei Mm.259929.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

BioGridi 230168. 1 interaction.
IntActi Q8R0W0. 1 interaction.
MINTi MINT-1866986.

PTM databases

PhosphoSitei Q8R0W0.

Proteomic databases

MaxQBi Q8R0W0.
PRIDEi Q8R0W0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 223650.
KEGGi mmu:223650.
UCSCi uc007wio.1. mouse.

Organism-specific databases

CTDi 83481.
MGIi MGI:2386306. Eppk1.

Phylogenomic databases

HOVERGENi HBG051491.

Miscellaneous databases

NextBioi 376784.
PROi Q8R0W0.
SOURCEi Search...

Gene expression databases

CleanExi MM_EPPK1.
Genevestigatori Q8R0W0.

Family and domain databases

Gene3Di 3.90.1290.10. 16 hits.
InterProi IPR001101. Plectin_repeat.
[Graphical view ]
Pfami PF00681. Plectin. 38 hits.
[Graphical view ]
SMARTi SM00250. PLEC. 77 hits.
[Graphical view ]
SUPFAMi SSF75399. SSF75399. 16 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Epiplakin gene analysis in mouse reveals a single exon encoding a 725-kDa protein with expression restricted to epithelial tissues."
    Spazierer D., Fuchs P., Proell V., Janda L., Oehler S., Fischer I., Hauptmann R., Wiche G.
    J. Biol. Chem. 278:31657-31666(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Strain: C57BL/6J.
    Tissue: Skin.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6318-6548.
    Tissue: Salivary gland.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1537; SER-2606; SER-3121; SER-3636; SER-4151; SER-4666; SER-5181; SER-5696 AND SER-6211, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  4. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
    Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
    J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2705; SER-3220; SER-3735; SER-4250; SER-4765; SER-5280; SER-5795 AND SER-6310, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  5. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
    Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
    Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiEPIPL_MOUSE
AccessioniPrimary (citable) accession number: Q8R0W0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: August 15, 2003
Last modified: May 14, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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