ID   Q8R041_MOUSE            Unreviewed;       134 AA.
AC   Q8R041;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 116.
DE   SubName: Full=Cck protein {ECO:0000313|EMBL:AAH28487.1};
DE   SubName: Full=Cholecystokinin {ECO:0000313|Ensembl:ENSMUSP00000150080.2};
GN   Name=Cck {ECO:0000313|Ensembl:ENSMUSP00000150080.2,
GN   ECO:0000313|MGI:MGI:88297};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH28487.1};
RN   [1] {ECO:0000313|EMBL:AAH28487.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Mammary gland {ECO:0000313|EMBL:AAH28487.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000150080.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000150080.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000150080.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000150080.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; BC028487; AAH28487.1; -; mRNA.
DR   RefSeq; NP_001271437.1; NM_001284508.2.
DR   ProteomicsDB; 334880; -.
DR   Antibodypedia; 29187; 300 antibodies from 34 providers.
DR   DNASU; 12424; -.
DR   Ensembl; ENSMUST00000216138.2; ENSMUSP00000150080.2; ENSMUSG00000032532.8.
DR   GeneID; 12424; -.
DR   UCSC; uc009sdh.3; mouse.
DR   AGR; MGI:88297; -.
DR   CTD; 885; -.
DR   MGI; MGI:88297; Cck.
DR   VEuPathDB; HostDB:ENSMUSG00000032532; -.
DR   GeneTree; ENSGT00390000003571; -.
DR   OrthoDB; 5293435at2759; -.
DR   BioGRID-ORCS; 12424; 2 hits in 77 CRISPR screens.
DR   ChiTaRS; Cck; mouse.
DR   Proteomes; UP000000589; Chromosome 9.
DR   Bgee; ENSMUSG00000032532; Expressed in primary motor cortex and 143 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; IEA:InterPro.
DR   InterPro; IPR015499; CCK-like.
DR   InterPro; IPR001651; Gastrin/CCK.
DR   PANTHER; PTHR10786; CHOLECYSTOKININ; 1.
DR   PANTHER; PTHR10786:SF0; CHOLECYSTOKININ; 1.
DR   Pfam; PF00918; Gastrin; 1.
PE   2: Evidence at transcript level;
KW   Amidation {ECO:0000256|ARBA:ARBA00022815};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..134
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015099307"
FT   DOMAIN          3..72
FT                   /note="Gastrin/cholecystokinin peptide hormone"
FT                   /evidence="ECO:0000259|Pfam:PF00918"
SQ   SEQUENCE   134 AA;  15163 MW;  9651DDD6C1D785E0 CRC64;
     MKSGVCLCVV MAVLAAGALA QPVVPAEATD PVEQRAQEAP RRQLRAVLRT DGEPRARLGA
     LLARYIQQVR KVAWMVTSGW VLTWTSRAGL KHRRWASFLW SSRTQFFLPA FEQPMACRPV
     CIWLDCSFWP HVRS
//