Q8QGU2 (Q8QGU2_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
FK506 binding protein 12.6 EMBL BAB89371.1

Submitted name:
Uncharacterized protein Ensembl ENSGALP00000026566

Gene names

Name:	FKBP12.6 EMBL BAB89371.1
Synonyms:	Gga.2210 Ensembl ENSGALP00000026566

Organism

Gallus gallus (Chicken) EMBL BAB89371.1

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the FKBP-type PPIase family. RuleBase RU004231

Ontologies

Keywords
Molecular function	Isomerase Rotamase RuleBase RU003715
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	brain development Inferred from expression pattern. Source: AgBase embryo development ending in birth or egg hatching Inferred from expression pattern Ref.2. Source: AgBase embryonic heart tube development Inferred from expression pattern Ref.2. Source: AgBase limb development Inferred from expression pattern. Source: AgBase lung development Inferred from expression pattern. Source: AgBase negative regulation of protein phosphatase type 2B activity Inferred from Biological aspect of Ancestor. Source: RefGenome protein folding Inferred from electronic annotation. Source: UniProtKB-KW regulation of ryanodine-sensitive calcium-release channel activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular component	calcium channel complex Inferred from Biological aspect of Ancestor. Source: RefGenome microsome Inferred from direct assay. Source: AgBase sarcoplasmic reticulum membrane Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular function	FK506 binding Inferred from Biological aspect of Ancestor. Source: RefGenome peptidyl-prolyl cis-trans isomerase activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8QGU2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 64F6E312FFEFA9F5	FASTA	108	11,957
	10 20 30 40 50 60 MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFRFK IGRQEVIKGF 70 80 90 100 EEGVTQMSLG QRAKLTCTPE MAYGATGHPG VIPPNATLLF DVELLRLE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution." International Chicken Genome Sequencing Consortium Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A. , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K. Nature 432:695-716(2004) [PubMed: 15592404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Red jungle fowl Ensembl ENSGALP00000026566.
[2]	"Heart-selective expression of the chicken FK506-binding protein (FKBP) 12.6 gene during embryonic development." Yazawa S., Obata K., Iio A., Koide M., Yokota M., Sasaki S., Kagami H., Ono T. Dev. Dyn. 226:33-41(2003) [PubMed: 12508222] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Leghorn EMBL BAB89371.1. Tissue: Brain EMBL BAB89371.1.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Red jungle fowl Ensembl ENSGALP00000026566.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AADN02018477 Genomic DNA. No translation available. AADN02018478 Genomic DNA. No translation available. AADN02018479 Genomic DNA. No translation available. AB074887 mRNA. Translation: BAB89371.1.
IPI	IPI00601848.
RefSeq	NP_989898.1. NM_204567.1.
UniGene	Gga.2210.
3D structure databases
HSSP	HSSP built from PDB template 1C9H based on UniProtKB Q16645.
ProteinModelPortal	Q8QGU2.
SMR	Q8QGU2. Positions 2-108.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8QGU2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSGALT00000026617; ENSGALP00000026566; ENSGALG00000016500.
GeneID	395254.
KEGG	gga:395254.
Organism-specific databases
CTD	2281.
Phylogenomic databases
eggNOG	veNOG20041.
GeneTree	ENSGT00550000074272.
HOGENOM	HBG731200.
HOVERGEN	HBG051623.
InParanoid	Q8QGU2.
OMA	DMAYGAT.
OrthoDB	EOG42NJ1X.
PhylomeDB	Q8QGU2.
Family and domain databases
InterPro	IPR023566. PPIase_FKBP. IPR001179. PPIase_FKBP_dom. [Graphical view]
KO	K09568.
PANTHER	PTHR10516. PPIase_FKBP. 1 hit.
Pfam	PF00254. FKBP_C. 1 hit. [Graphical view]
PROSITE	PS50059. FKBP_PPIASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8QGU2_CHICK

Accession

Primary (citable) accession number: Q8QGU2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	November 16, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)