Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mothers against decapentaplegic homolog

Gene

Smad8A

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Mothers against decapentaplegic homologUniRule annotation
Short name:
MAD homologUniRule annotation
Short name:
Mothers against DPP homologUniRule annotation
Alternative name(s):
SMAD family memberUniRule annotation
Gene namesi
Name:Smad8AImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ8QGG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 140MH1InterPro annotationAdd BLAST125
Domaini272 – 466MH2InterPro annotationAdd BLAST195

Sequence similaritiesi

Belongs to the dwarfin/SMAD family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG053353.
KOiK16791.

Family and domain databases

Gene3Di2.60.200.10. 1 hit.
3.90.520.10. 1 hit.
InterProiView protein in InterPro
IPR013790. Dwarfin.
IPR003619. MAD_homology1_Dwarfin-type.
IPR013019. MAD_homology_MH1.
IPR017855. SMAD_dom-like.
IPR001132. SMAD_dom_Dwarfin-type.
IPR008984. SMAD_FHA_domain.
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiView protein in Pfam
PF03165. MH1. 1 hit.
PF03166. MH2. 1 hit.
SMARTiView protein in SMART
SM00523. DWA. 1 hit.
SM00524. DWB. 1 hit.
SUPFAMiSSF49879. SSF49879. 1 hit.
SSF56366. SSF56366. 1 hit.
PROSITEiView protein in PROSITE
PS51075. MH1. 1 hit.
PS51076. MH2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8QGG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHASTPISSL FTFTSPAVKR LLGWKQGDEE EKWAEKAVDS LVKKLKKKKG
60 70 80 90 100
AMEELERALS CPGQPSKCVT IPRSLDGRLQ VSHRKGLSHV IYCRVWRWPD
110 120 130 140 150
LQSHHELKPM ECCEFPFGSK QKDVCINPYH YRRVETPVLP PVLVPRHSEF
160 170 180 190 200
NPQLSLLAKF SNTSLNNEPL MPHNATFPES FQQPPRTPFS SSPSNIFPQS
210 220 230 240 250
PNTVGYPDSP RSSTDPGSPP YQITETPPPP YNAPDLQGNQ NRPTADPAEC
260 270 280 290 300
QLVLSALNRD FRPVCYEEPL HWCSVAYYEL NNRVGETFQA SARSVLIDGF
310 320 330 340 350
TDPSNNKNRF CLGLLSNVNR NSTIENTRRH IGKGVHLYYV GGEVYAECVS
360 370 380 390 400
DSSIFVQSRN CNYQHGFHPS TVCKIPSGCS LKIFNNQLFA QLLSQSVNQG
410 420 430 440 450
FEVVYELTKM CTIRMSFVKG WGAEYHRQDV TSTPCWIEIH LHGPLQWLDK
460
VLTQMGSPHN PISSVS
Length:466
Mass (Da):52,559
Last modified:June 1, 2002 - v1
Checksum:iDC2453E9960A08B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF464927 mRNA. Translation: AAL86772.1.
RefSeqiNP_001165671.1. NM_001172200.1.
UniGeneiXl.741.
Xl.85567.

Genome annotation databases

GeneIDi100337601.
KEGGixla:100337601.

Similar proteinsi

Entry informationi

Entry nameiQ8QGG6_XENLA
AccessioniPrimary (citable) accession number: Q8QGG6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: September 27, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)