ID   Q8QDX5_9HIV1            Unreviewed;       545 AA.
AC   Q8QDX5;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   22-FEB-2023, entry version 102.
DE   SubName: Full=Envelope glycoprotein {ECO:0000313|EMBL:AAL78482.1};
DE   Flags: Fragment;
GN   Name=env {ECO:0000313|EMBL:AAL78482.1};
OS   Human immunodeficiency virus 1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11676 {ECO:0000313|EMBL:AAL78482.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:AAL78482.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=98BY10443 {ECO:0000313|EMBL:AAL78482.1};
RX   PubMed=14601597; DOI=10.1089/088922203322493139;
RA   Masharsky A.E., Klimov N.A., Kozlov A.P.;
RT   "Molecular cloning and analysis of full-length genome of HIV type 1 strains
RT   prevalent in countries of the former Soviet Union.";
RL   AIDS Res. Hum. Retroviruses 19:933-939(2003).
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DR   EMBL; AF414002; AAL78482.1; -; Genomic_DNA.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.210; -; 1.
DR   Gene3D; 2.170.40.20; Human immunodeficiency virus 1, Gp160, envelope glycoprotein; 2.
DR   InterPro; IPR036377; Gp120_core_sf.
DR   InterPro; IPR000777; HIV1_Gp120.
DR   Pfam; PF00516; GP120; 2.
DR   SUPFAM; SSF56502; gp120 core; 2.
DR   SUPFAM; SSF58069; Virus ectodomain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Viral envelope protein {ECO:0000313|EMBL:AAL78482.1};
KW   Virion {ECO:0000313|EMBL:AAL78482.1}.
FT   TRANSMEM        488..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          27..135
FT                   /note="Human immunodeficiency virus 1 envelope glycoprotein
FT                   Gp120"
FT                   /evidence="ECO:0000259|Pfam:PF00516"
FT   DOMAIN          132..487
FT                   /note="Human immunodeficiency virus 1 envelope glycoprotein
FT                   Gp120"
FT                   /evidence="ECO:0000259|Pfam:PF00516"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAL78482.1"
FT   NON_TER         545
FT                   /evidence="ECO:0000313|EMBL:AAL78482.1"
SQ   SEQUENCE   545 AA;  60567 MW;  CD3457DF29CDEEC7 CRC64;
     KEIRKHLWRW GTLFLGMLMT CNATENLWVT VYYGVPVWKE ATTTLFCASD AKAYSKEVHN
     VWATYACVPT DPSPQEIPLE NVTENFNMGK NNMVEQMHED IISLWDQSLK PCVKLTPLCV
     TLNCTDLKKN VTNNNTISPE MREMKNCSFN ITTGLRNKVK NEYALFYELD VVQINNDSYR
     LISCNTSVVT QACPKISFEP IPIHYCAPAG FAILKCNDKE FNGTGPCTNV STVQCTHGIK
     PVVSTQLLLN GSLAEKEVVI RSVNFTDNTK TIIVQLTEPV EINCTRPNNN TRKGIHIGPG
     RAFYVTGDII GDIRQAHCNI STTKWNNTLK QIGDKLKEQF GNKTIVFNQS SGGDPEIVMH
     SFNCGGEFFY CNTTGLFNST WNGTESNNTI TLPCRIKQII NMWQEVGKAM YAPPIAGQIR
     CSSNITGLLL TRDGGDQSNG TEIFRPGGGD MRDNWRSELY KYKVVKIEPL GVAPAKAKRR
     VVQREKRAVG IGAVFLGFLG AAGSTMGAAS ITLTVQARQL LSGIVQQQNN LLRAIEAQQH
     LLQLT
//