Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Envelope glycoprotein

Gene

env

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Fusion of virus membrane with host membraneSAAS annotation, Host-virus interaction, Viral attachment to host cellSAAS annotation, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Submitted name:
Envelope glycoproteinImported
Gene namesi
Name:envImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Virion membrane SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei488 – 511HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Viral envelope proteinImported, Virion

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ8QDX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 135GP120InterPro annotationAdd BLAST109
Domaini132 – 487GP120InterPro annotationAdd BLAST356

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di2.170.40.20. 2 hits.
InterProiIPR000777. HIV1_GP160.
[Graphical view]
PfamiPF00516. GP120. 2 hits.
[Graphical view]
SUPFAMiSSF56502. SSF56502. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q8QDX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KEIRKHLWRW GTLFLGMLMT CNATENLWVT VYYGVPVWKE ATTTLFCASD
60 70 80 90 100
AKAYSKEVHN VWATYACVPT DPSPQEIPLE NVTENFNMGK NNMVEQMHED
110 120 130 140 150
IISLWDQSLK PCVKLTPLCV TLNCTDLKKN VTNNNTISPE MREMKNCSFN
160 170 180 190 200
ITTGLRNKVK NEYALFYELD VVQINNDSYR LISCNTSVVT QACPKISFEP
210 220 230 240 250
IPIHYCAPAG FAILKCNDKE FNGTGPCTNV STVQCTHGIK PVVSTQLLLN
260 270 280 290 300
GSLAEKEVVI RSVNFTDNTK TIIVQLTEPV EINCTRPNNN TRKGIHIGPG
310 320 330 340 350
RAFYVTGDII GDIRQAHCNI STTKWNNTLK QIGDKLKEQF GNKTIVFNQS
360 370 380 390 400
SGGDPEIVMH SFNCGGEFFY CNTTGLFNST WNGTESNNTI TLPCRIKQII
410 420 430 440 450
NMWQEVGKAM YAPPIAGQIR CSSNITGLLL TRDGGDQSNG TEIFRPGGGD
460 470 480 490 500
MRDNWRSELY KYKVVKIEPL GVAPAKAKRR VVQREKRAVG IGAVFLGFLG
510 520 530 540
AAGSTMGAAS ITLTVQARQL LSGIVQQQNN LLRAIEAQQH LLQLT
Length:545
Mass (Da):60,567
Last modified:June 1, 2002 - v1
Checksum:iCD3457DF29CDEEC7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei545Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF414002 Genomic DNA. Translation: AAL78482.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF414002 Genomic DNA. Translation: AAL78482.1.

3D structure databases

ProteinModelPortaliQ8QDX5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.170.40.20. 2 hits.
InterProiIPR000777. HIV1_GP160.
[Graphical view]
PfamiPF00516. GP120. 2 hits.
[Graphical view]
SUPFAMiSSF56502. SSF56502. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8QDX5_9HIV1
AccessioniPrimary (citable) accession number: Q8QDX5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: July 6, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.