Envelope glycoprotein - Human immunodeficiency virus 1

Preferred order of sections

Names and origin

Protein names

Submitted name:
Envelope glycoprotein EMBL BAB85748.1

Gene names

Name:

env EMBL BAB85748.1

Organism

Human immunodeficiency virus 1 EMBL BAB85748.1

Taxonomic identifier

11676 [NCBI]

Taxonomic lineage

Viruses › Retro-transcribing viruses › Retroviridae › Orthoretrovirinae › Lentivirus › Primate lentivirus group

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	207 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

Ontologies

Keywords
Biological process	Fusion of virus membrane with host membrane SAAS SAAS000777 Host-virus interaction Viral attachment to host cell SAAS SAAS000777 Viral penetration into host cytoplasm Virus entry into host cell
Cellular component	Viral envelope protein EMBL BAB85748.1 Virion
PTM	Disulfide bond SAAS SAAS000777
Technical term	3D-structure PDB 2NY6
Gene Ontology (GO)
Biological_process	viral attachment to host cell Inferred from electronic annotation. Source: UniProtKB-KW viral entry into host cell Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	viral envelope Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Amino acid modifications

Glycosylation

110

1

N-linked (GlcNAc...) PDB 2NY6

Glycosylation

138

1

N-linked (GlcNAc...) PDB 2NY6

Glycosylation

152

1

N-linked (GlcNAc...) PDB 2NY6

Glycosylation

165

1

N-linked (GlcNAc...) PDB 2NY6

Glycosylation

171

1

N-linked (GlcNAc...) PDB 2NY6

Experimental info

Non-terminal residue

Non-terminal residue

1

Sequences

Sequence

Length

Mass (Da)

Tools

Q8Q7Z9 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: BB1255A4F09ADE69
Show »

FASTA

207

22,760

        10         20         30         40         50         60 
LCVSLKCTDL KNDTNTNSSS GRMIMEKGEI KNCSFNISTS KRGKVQKEYA FFYKLDIIPI 

        70         80         90        100        110        120 
DNDTTSYTLT SCNTSVITQA CPKVSFEPIP IHYCAPAGFA ILKCNNKTFN GTGPCTNVST 

       130        140        150        160        170        180 
VQCTHGIRPV VSTQLLLNGS LAEEEVVIRS VNFTDNAKTI IVQLNTSVEI NCTRPTNNTR 

       190        200 
KKIRIQRGPG RAFVTIGKIG NMRQAHC

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References

[1]

"Multiple HIV-1 infection of homogenous R5 and varied X4 viruses in a case with acute infection."
Takeuchi H., Suzuki Y., Daar E.S., Koyanagi Y.
Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

[2]

"Structural definition of a conserved neutralization epitope on HIV-1 gp120."
Zhou T., Xu L., Dey B., Hessell A.J., Van Ryk D., Xiang S.H., Yang X., Zhang M.Y., Zwick M.B., Arthos J., Burton D.R., Dimitrov D.S., Sodroski J., Wyatt R., Nabel G.J., Kwong P.D.
Nature 445:732-737(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 71-173, GLYCOSYLATION AT ASN-110; ASN-138; ASN-152; ASN-165 AND ASN-171.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AB077815 Genomic DNA. Translation: BAB85748.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NY6	X-ray	2.80	A	71-173	[»]

ProteinModelPortal

Q8Q7Z9.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.170.40.20. 1 hit.

InterPro

IPR000777. HIV1_GP160.
[Graphical view]

Pfam

PF00516. GP120. 1 hit.
[Graphical view]

SUPFAM

SSF56502. GP120. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q8Q7Z9.

Entry information

Entry name

Q8Q7Z9_9HIV1

Accession

Primary (citable) accession number: Q8Q7Z9

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	March 6, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)