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Protein
Submitted name:

Envelope glycoprotein

Gene

env

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Fusion of virus membrane with host membraneSAAS annotation, Host-virus interaction, Viral attachment to host cellSAAS annotation, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Submitted name:
Envelope glycoproteinImported
Gene namesi
Name:envImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MembraneSAAS annotation, Viral envelope proteinImported, Virion

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi? ↔ 81Combined sources
Disulfide bondi? ↔ 72Combined sources
Disulfide bondi94 ↔ 123Combined sources
Disulfide bondi104 ↔ 115Combined sources
Glycosylationi110 – 1101N-linked (GlcNAc...)Combined sources
Glycosylationi138 – 1381N-linked (GlcNAc...)Combined sources
Glycosylationi152 – 1521N-linked (GlcNAc...)Combined sources
Glycosylationi165 – 1651N-linked (GlcNAc...)Combined sources
Glycosylationi171 – 1711N-linked (GlcNAc...)Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NY6X-ray2.80A71-173[»]
ProteinModelPortaliQ8Q7Z9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8Q7Z9.

Family & Domainsi

Family and domain databases

Gene3Di2.170.40.20. 1 hit.
InterProiIPR000777. HIV1_GP160.
[Graphical view]
PfamiPF00516. GP120. 1 hit.
[Graphical view]
SUPFAMiSSF56502. SSF56502. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8Q7Z9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LCVSLKCTDL KNDTNTNSSS GRMIMEKGEI KNCSFNISTS KRGKVQKEYA
60 70 80 90 100
FFYKLDIIPI DNDTTSYTLT SCNTSVITQA CPKVSFEPIP IHYCAPAGFA
110 120 130 140 150
ILKCNNKTFN GTGPCTNVST VQCTHGIRPV VSTQLLLNGS LAEEEVVIRS
160 170 180 190 200
VNFTDNAKTI IVQLNTSVEI NCTRPTNNTR KKIRIQRGPG RAFVTIGKIG

NMRQAHC
Length:207
Mass (Da):22,760
Last modified:June 1, 2002 - v1
Checksum:iBB1255A4F09ADE69
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei207 – 2071Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB077815 Genomic DNA. Translation: BAB85748.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB077815 Genomic DNA. Translation: BAB85748.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NY6X-ray2.80A71-173[»]
ProteinModelPortaliQ8Q7Z9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ8Q7Z9.

Family and domain databases

Gene3Di2.170.40.20. 1 hit.
InterProiIPR000777. HIV1_GP160.
[Graphical view]
PfamiPF00516. GP120. 1 hit.
[Graphical view]
SUPFAMiSSF56502. SSF56502. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Multiple HIV-1 infection of homogenous R5 and varied X4 viruses in a case with acute infection."
    Takeuchi H., Suzuki Y., Daar E.S., Koyanagi Y.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 71-173, DISULFIDE BONDS, GLYCOSYLATION AT ASN-110; ASN-138; ASN-152; ASN-165 AND ASN-171.

Entry informationi

Entry nameiQ8Q7Z9_9HIV1
AccessioniPrimary (citable) accession number: Q8Q7Z9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: May 27, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.