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Reviewed, UniProtKB/Swiss-Prot Q8PZN6 (PGP_METMA)

Last modified June 16, 2009. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phosphoglycolate phosphatase
      Short name=PGPase
      Short name=PGP
    EC=3.1.3.18
Gene names
Ordered Locus Names: MM_0456
OrganismMethanosarcina mazei (Methanosarcina frisia) [Complete proteome] [HAMAP]
Taxonomic identifier2209 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

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Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the dephosphorylation of 2-phosphoglycolate By similarity.

Catalytic activity

2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_01419

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the archaeal SPP-like hydrolase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycolate phosphatase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 226226Phosphoglycolate phosphatase HAMAP MF_01419
PRO_0000146719

Sites

Active site91Nucleophile By similarity
Metal binding91Magnesium By similarity
Metal binding111Magnesium By similarity
Metal binding1731Magnesium By similarity
Metal binding1771Magnesium By similarity
Binding site1501Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q8PZN6-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 9ED4C75961057A5D

FASTA22624,677
        10         20         30         40         50         60 
MKFKALVIDI DGTITCKNRE LHLGAVKKMR TLNVPVVLAT GNILCYARTA SRLIGLGGAV 

        70         80         90        100        110        120 
IAENGGAVTV RYDVNGIFEG SLEECEKAFS FLSQHFKLTK LDPTYRKTEI ALRRDFDLEE 

       130        140        150        160        170        180 
ARSLLETQPF DIELVDTKYA IHIKSIKINK GIGLQKLAGM MGFEAEDFVA IGDSANDAEM 

       190        200        210        220 
FEAAGFGIAV ANGDERVKEV ANYVTEASFG DGAVEAIEFL ESNGWI

« Hide

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References

[1]"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R. expand/collapse author list , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed: 12125824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11883 / OCM 88.

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Cross-references

Sequence databases

AE008384 Genomic DNA. Translation: AAM30152.1.
RefSeqNP_632480.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1478798.
GenomeReviewsGene locus MM_0456 in contig AE008384_GR.
KEGGmma:MM_0456.
NMPDRfig|192952.1.peg.456.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8PZN6.
OMAQ8PZN6. LEEVICI.

Enzyme and pathway databases

BioCycMMAZ192952:MM0456-MON.
BRENDA3.1.3.18. 261165.

Family and domain databases

HAMAPMF_01419.
[Tree]
InterProIPR013200. HAD-SF_hydro-like_3.
IPR006379. HAD-SF_hydro_IIB.
IPR006382. SPPlik_hydro_arc.
IPR006378. Suc_phosP.
[Graphical view]
PfamPF08282. Hydrolase_3. 2 hits.
[Graphical view]
TIGRFAMsTIGR01484. HAD-SF-IIB. 1 hit.
TIGR01487. SPP-like. 1 hit.
TIGR01482. SPP-subfamily. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePGP_METMA
AccessionPrimary (citable) accession number: Q8PZN6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: October 1, 2002
Last modified: June 16, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents