ID   Q8PX93_METMA            Unreviewed;       689 AA.
AC   Q8PX93;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 118.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAM31025.1};
GN   OrderedLocusNames=MM_1329 {ECO:0000313|EMBL:AAM31025.1};
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM31025.1, ECO:0000313|Proteomes:UP000000595};
RN   [1] {ECO:0000313|EMBL:AAM31025.1, ECO:0000313|Proteomes:UP000000595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC   {ECO:0000313|Proteomes:UP000000595};
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA   Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA   Fritz H.J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE008384; AAM31025.1; -; Genomic_DNA.
DR   RefSeq; WP_011033275.1; NC_003901.1.
DR   AlphaFoldDB; Q8PX93; -.
DR   DNASU; 1479671; -.
DR   GeneID; 82160370; -.
DR   KEGG; mma:MM_1329; -.
DR   PATRIC; fig|192952.21.peg.1543; -.
DR   eggNOG; arCOG02344; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR032255; HBM.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM01358; HBM; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51753; HBM; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          37..293
FT                   /note="HBM"
FT                   /evidence="ECO:0000259|PROSITE:PS51753"
FT   DOMAIN          320..372
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          391..627
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   DOMAIN          578..640
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
SQ   SEQUENCE   689 AA;  76635 MW;  AC432EC366EC56C5 CRC64;
     MYKSTKIGHV VIGFALLLIL IFFVGYTGYQ GMNEVDKKSR AIQNMTFIMN NMQDALQAEE
     SYVIHGDPAY KKEVYHYLSF VPTQAEISKV IYIGYLDPEN RDRMDLVLEA SREFNETFNR
     YVEAEDEQAK VRSKLVNDSE ILIINADKLS KNQMVQYREE FEAGYSNETL EKKFSNAESA
     QRIIVLTMKA QNEYQNYAMS PDQQYADNFN VFMEEIIELS TDLNRRMDRP ENIAAGNEIL
     RSAEDFQADF EQFKVLEERK TLEEKNMMSI ATRVGEVAEA ASADQKEKLD VLITNSVNKI
     FLVTFLSLLI GGLLVFVIMN IYRKPINELL EASDMVSEGN LDVDIKGSSR SEIFQLSEAF
     KAMVENLCSL IKEIQEGSLH LATLSEEMSA SSEEVASASR RISETAAEIS NGAEVQSTKI
     IDITHAMQDM THNIQEIADN TQKVSKSTNL VNDTVYNIGN VSRDVLLKMD LISSSVDETE
     IVIKDLDSKS QQINEIITLI TRIADQTNML ALNAAIEAAR AGEHGRGFSV VADEVRKLAE
     ESGTAAKDIS RLIDEIRESI SDTVESIDAS KKNVKNGSLS VSEEVEMVTG IVSTINEITN
     MIEDVAAATE EQSASIEEIT STLEDISSIS EQSAAGTQET AAALEEQSAS MAELASMAND
     LSLLGEKMKK VTEKFRLGNS KGESENISD
//