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Q8PX04

- APGM_METMA

UniProt

Q8PX04 - APGM_METMA

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Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

apgM

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.By similarity

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.

Pathwayi

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. phosphoglycerate mutase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Glycolysis

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-1456-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC:5.4.2.12)
Short name:
BPG-independent PGAM
Short name:
Phosphoglyceromutase
Short name:
aPGAM
Gene namesi
Name:apgM
Ordered Locus Names:MM_1418
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3973972,3-bisphosphoglycerate-independent phosphoglycerate mutasePRO_0000138137Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_1418.

Structurei

3D structure databases

ProteinModelPortaliQ8PX04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3635.
HOGENOMiHOG000004785.
KOiK15635.
OMAiYRHLMVW.

Family and domain databases

Gene3Di3.40.720.10. 2 hits.
HAMAPiMF_01402_A. ApgM_A.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR013371. Homoserine_kinase_put.
IPR006124. Metalloenzyme.
[Graphical view]
PfamiPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFiPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
TIGRFAMsiTIGR00306. apgM. 1 hit.
TIGR02535. hyp_Hser_kinase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PX04-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYAILIGDG MADYPIEKLG NRTILQAART PAMDSIAARG RAGLAKTVPD
60 70 80 90 100
SFPPGSDVAN MSILGYDPAT YYSGRAPLEA ASMGVALAAD DVAFRCNLIT
110 120 130 140 150
TEHGMIKDYS AGHISSDEAE ILIDTLDYEL STENIRFYPG ISYRHLIVAG
160 170 180 190 200
NNLGAETECT PPHDITGEKI DKYLPRGKDG EFFSELIEAS KVVLELHPVN
210 220 230 240 250
LKRVEEGKNP ANSIWVWGQG YAPKFTAFMK LYGKKGAVIS AVDLLKGIGI
260 270 280 290 300
YAGLDVIEVH GATGYLDTNY EGKVRAAIEA LKTRDLVFVH VEAPDEAGHE
310 320 330 340 350
GSIEKKLKAV EDFDSRIVAP ILEYAENSDE PFTILVLPDH PTPISVKTHT
360 370 380 390
RDPIPFAIYR TDKPETDNVE AFDEESVKNG SMGLVKASDL IGILIKS
Length:397
Mass (Da):43,175
Last modified:October 10, 2002 - v1
Checksum:iFFB8BC932E9E15EC
GO

Sequence cautioni

The sequence AAM31114.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31114.1. Different initiation.
RefSeqiNP_633442.2. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM31114; AAM31114; MM_1418.
GeneIDi1479760.
KEGGimma:MM_1418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31114.1 . Different initiation.
RefSeqi NP_633442.2. NC_003901.1.

3D structure databases

ProteinModelPortali Q8PX04.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_1418.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM31114 ; AAM31114 ; MM_1418 .
GeneIDi 1479760.
KEGGi mma:MM_1418.

Phylogenomic databases

eggNOGi COG3635.
HOGENOMi HOG000004785.
KOi K15635.
OMAi YRHLMVW.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00186 .
BioCyci MMAZ192952:GCK2-1456-MONOMER.

Family and domain databases

Gene3Di 3.40.720.10. 2 hits.
HAMAPi MF_01402_A. ApgM_A.
InterProi IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR013371. Homoserine_kinase_put.
IPR006124. Metalloenzyme.
[Graphical view ]
Pfami PF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view ]
PIRSFi PIRSF006392. IPGAM_arch. 1 hit.
SUPFAMi SSF53649. SSF53649. 2 hits.
TIGRFAMsi TIGR00306. apgM. 1 hit.
TIGR02535. hyp_Hser_kinase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiAPGM_METMA
AccessioniPrimary (citable) accession number: Q8PX04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: October 1, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3