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Protein

Nascent polypeptide-associated complex protein

Gene

nac

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Contacts the emerging nascent chain on the ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2069-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nascent polypeptide-associated complex proteinUniRule annotation
Gene namesi
Name:nacUniRule annotation
Ordered Locus Names:MM_2015
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000000595 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 120120Nascent polypeptide-associated complex proteinPRO_0000135605Add
BLAST

Interactioni

Subunit structurei

Homodimer. Interacts with the ribosome. Binds ribosomal RNA.UniRule annotation

Protein-protein interaction databases

STRINGi192952.MM_2015.

Structurei

3D structure databases

ProteinModelPortaliQ8PVF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 8069NAC-A/BUniRule annotationAdd
BLAST
Domaini81 – 11838UBAUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the NAC-alpha family.UniRule annotation
Contains 1 NAC-A/B (NAC-alpha/beta) domain.UniRule annotation
Contains 1 UBA domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Family and domain databases

HAMAPiMF_00814. NAC_arch.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8PVF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPGMGGVGG RGMNPAKMKQ MMKQMGIDVK ELKDVEEVVI KTADSNIVIE
60 70 80 90 100
NANVTIMTVQ GSETYQIVGD VKEVPKSLEI PAEDIKLVME QTGVSEEEAR
110 120
NALKNSNGDL AEAIVALSSA
Length:120
Mass (Da):12,839
Last modified:October 1, 2002 - v1
Checksum:iB65C0210ABB68C01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31711.1.
RefSeqiWP_011033947.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM31711; AAM31711; MM_2015.
GeneIDi24881697.
KEGGimma:MM_2015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31711.1.
RefSeqiWP_011033947.1. NC_003901.1.

3D structure databases

ProteinModelPortaliQ8PVF0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192952.MM_2015.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM31711; AAM31711; MM_2015.
GeneIDi24881697.
KEGGimma:MM_2015.

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2069-MONOMER.

Family and domain databases

HAMAPiMF_00814. NAC_arch.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiNAC_METMA
AccessioniPrimary (citable) accession number: Q8PVF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 1, 2002
Last modified: May 11, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.