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Protein

Ribonuclease P protein component 1

Gene

rnp1

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2186-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 1UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 1UniRule annotation
Alternative name(s):
Rpp29UniRule annotation
Gene namesi
Name:rnp1UniRule annotation
Ordered Locus Names:MM_2132
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110Ribonuclease P protein component 1PRO_0000128431Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi192952.MM_2132.

Structurei

3D structure databases

ProteinModelPortaliQ8PV42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1588.
HOGENOMiHOG000231353.
KOiK03538.
OMAiQPENRIP.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
HAMAPiMF_00754. RNase_P_1.
InterProiIPR002730. RNase_P/MRP_p29.
IPR023538. RNP1.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PV42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSKVEILPS TLIFHELIGL EIKVSNSTNP SLIGIRGRVI NETKNMLVVE
60 70 80 90 100
NSESRELKIP KADSEFVFRI PAELSEKGRR SDIFVKIQGN LLLSQPENRI
110
KNIKKLRKWG
Length:110
Mass (Da):12,582
Last modified:October 1, 2002 - v1
Checksum:i4D94C0DEC0981940
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31828.1.
RefSeqiNP_634156.1. NC_003901.1.
WP_011034063.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM31828; AAM31828; MM_2132.
GeneIDi1480474.
KEGGimma:MM_2132.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31828.1.
RefSeqiNP_634156.1. NC_003901.1.
WP_011034063.1. NC_003901.1.

3D structure databases

ProteinModelPortaliQ8PV42.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192952.MM_2132.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM31828; AAM31828; MM_2132.
GeneIDi1480474.
KEGGimma:MM_2132.

Phylogenomic databases

eggNOGiCOG1588.
HOGENOMiHOG000231353.
KOiK03538.
OMAiQPENRIP.

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2186-MONOMER.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
HAMAPiMF_00754. RNase_P_1.
InterProiIPR002730. RNase_P/MRP_p29.
IPR023538. RNP1.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiRNP1_METMA
AccessioniPrimary (citable) accession number: Q8PV42
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: October 1, 2002
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.