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Protein

DNA-directed RNA polymerase subunit A''

Gene

rpoA2

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2327-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A''UniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoA2UniRule annotation
Ordered Locus Names:MM_2270
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000000595 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408DNA-directed RNA polymerase subunit A''PRO_0000074016Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi192952.MM_2270.

Structurei

3D structure databases

ProteinModelPortaliQ8PUR2.
SMRiQ8PUR2. Positions 232-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PUR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSISEATVD SMIKDLPLPS NILKTLRDDV IKAGVSKKEM EEIIERVMEE
60 70 80 90 100
YTVSCIEPCD AAGVVAAQSI GEPGTQMTMR TFHYAGVAEI NVTLGLPRLI
110 120 130 140 150
EIVDARKIPS TPMMTIALSK EHPEDYAYDR EKTRALAWEI EATKIDHIAD
160 170 180 190 200
VTTDLSQMKL IIDLHEKAME GRNITIDRVK EKFNEELNVL VSISPDIDNQ
210 220 230 240 250
IVITPGEPSY RELLQLAKSI HNVTLKGIEG IKRVVVRKEG EEYTLYTEGS
260 270 280 290 300
ALREVLQFEG VDRTRTSTNN INEIYEVLGI EAARNAIIKE ATDTLREQGL
310 320 330 340 350
TVDIRHIMLV ADLMTSDGEV KQIGRHGISG EKASVFARAA FEVTVNHLLD
360 370 380 390 400
AGMRGYVDQL QGVTENIIVG QPIRMGTGDV HLISRKAEKV VEVPPEIETA

EEIEVEEG
Length:408
Mass (Da):45,332
Last modified:October 10, 2002 - v1
Checksum:i72B511B9431E338D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31966.1.

Genome annotation databases

EnsemblBacteriaiAAM31966; AAM31966; MM_2270.
KEGGimma:MM_2270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008384 Genomic DNA. Translation: AAM31966.1.

3D structure databases

ProteinModelPortaliQ8PUR2.
SMRiQ8PUR2. Positions 232-385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192952.MM_2270.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM31966; AAM31966; MM_2270.
KEGGimma:MM_2270.

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2327-MONOMER.

Family and domain databases

HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOA2_METMA
AccessioniPrimary (citable) accession number: Q8PUR2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: November 11, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.