Q8PTU3 (RNP3_METMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 3
Short name=RNase P component 3
EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	MM_2618

Organism

Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) [Complete proteome] [HAMAP]

Taxonomic identifier

192952 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	239 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 239	239	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_0000140041

Sequences

	Sequence		Length	Mass (Da)
	Q8PTU3 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 4753C3632EAA7063	FASTA	239	26,002
	10 20 30 40 50 60 MGKPEFYDFC VHAVPDGANA VEELSSLSRH LGYSGIALAN HSDKLPSKKP VLPSIEGFEV 70 80 90 100 110 120 FRGIELVEEN PSKLHGLVGK FRSSMDVLIV HGGSEAVNRA ALENPRVDIL NHPAFDKSSG 130 140 150 160 170 180 LNQVLAKAAA ENGVAIGITL RPLLHSRGSR RIRMLSDLKA NLELARKYDV PLVLCSDAMS 190 200 210 220 230 CYDLRSPMET LAFAEVCGLE EDEALDALST VPKKIIKKNR PGPGYVREGI EVLEGEDIF

References

[1]

"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea." Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R. , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G. J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed: 12125824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008384 Genomic DNA. Translation: AAM32314.1.
RefSeq	NP_634642.1. NC_003901.1.
3D structure databases
ProteinModelPortal	Q8PTU3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1480960.
GenomeReviews	Gene locus MM_2618 in contig AE008384_GR.
KEGG	mma:MM_2618.
NMPDR	fig|192952.1.peg.2618.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG551632.
OMA	RFAVEQP.
ProtClustDB	PRK00912.
Enzyme and pathway databases
BioCyc	MMAZ192952:MM2618-MONOMER.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR023539. RNase_P_comp-3. IPR002738. RNase_P_p30. [Graphical view]
KO	K03539.
PANTHER	PTHR13031. RNase_P_p30. 1 hit.
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP3_METMA

Accession

Primary (citable) accession number: Q8PTU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	October 1, 2002
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program