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Q8PTU3 (RNP3_METMA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 3

Short name=RNase P component 3
EC=3.1.26.5
Alternative name(s):
Rpp30
Gene names
Name:rnp3
Ordered Locus Names:MM_2618
OrganismMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) [Complete proteome] [HAMAP]
Taxonomic identifier192952 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits Potential.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00756.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239Ribonuclease P protein component 3 HAMAP-Rule MF_00756
PRO_0000140041

Sequences

Sequence LengthMass (Da)Tools
Q8PTU3 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 4753C3632EAA7063

FASTA23926,002
        10         20         30         40         50         60 
MGKPEFYDFC VHAVPDGANA VEELSSLSRH LGYSGIALAN HSDKLPSKKP VLPSIEGFEV 

        70         80         90        100        110        120 
FRGIELVEEN PSKLHGLVGK FRSSMDVLIV HGGSEAVNRA ALENPRVDIL NHPAFDKSSG 

       130        140        150        160        170        180 
LNQVLAKAAA ENGVAIGITL RPLLHSRGSR RIRMLSDLKA NLELARKYDV PLVLCSDAMS 

       190        200        210        220        230 
CYDLRSPMET LAFAEVCGLE EDEALDALST VPKKIIKKNR PGPGYVREGI EVLEGEDIF 

« Hide

References

[1]"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R. expand/collapse author list , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008384 Genomic DNA. Translation: AAM32314.1.
RefSeqNP_634642.1. NC_003901.1.

3D structure databases

ProteinModelPortalQ8PTU3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING192952.MM_2618.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM32314; AAM32314; MM_2618.
GeneID1480960.
KEGGmma:MM_2618.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1603.
HOGENOMHOG000229552.
KOK03539.
OMAESFIAPG.

Enzyme and pathway databases

BioCycMMAZ192952:GCK2-2678-MONOMER.

Family and domain databases

HAMAPMF_00756. RNase_P_3.
InterProIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERPTHR13031. PTHR13031. 1 hit.
PfamPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP3_METMA
AccessionPrimary (citable) accession number: Q8PTU3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: October 1, 2002
Last modified: July 9, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families