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Q8PTU2

- RNP2_METMA

UniProt

Q8PTU2 - RNP2_METMA

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Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciMMAZ192952:GCK2-2679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:MM_2619
OrganismiMethanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic identifieri192952 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000000595: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 116116Ribonuclease P protein component 2PRO_0000140022Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi192952.MM_2619.

Structurei

3D structure databases

ProteinModelPortaliQ8PTU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1369.
HOGENOMiHOG000286243.
KOiK03537.
OMAiNPWLIDY.

Family and domain databases

HAMAPiMF_00755. RNase_P_2.
InterProiIPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFiPIRSF004952. RNase_P_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8PTU2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKRLLPSLRA KKRYLAFELI SEEPASRSDI VKEVMSSASS LLGDVTTSDC
60 70 80 90 100
DIRVLGFENG KGIIQCSHTK VKQTRASLAA LTRINGKRAT LHVLGVSGTV
110
KRATEKFLQD EGVFSS
Length:116
Mass (Da):12,653
Last modified:October 1, 2002 - v1
Checksum:iF4FE4B094476C847
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32315.1.
RefSeqiNP_634643.1. NC_003901.1.

Genome annotation databases

EnsemblBacteriaiAAM32315; AAM32315; MM_2619.
GeneIDi1480961.
KEGGimma:MM_2619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008384 Genomic DNA. Translation: AAM32315.1 .
RefSeqi NP_634643.1. NC_003901.1.

3D structure databases

ProteinModelPortali Q8PTU2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 192952.MM_2619.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM32315 ; AAM32315 ; MM_2619 .
GeneIDi 1480961.
KEGGi mma:MM_2619.

Phylogenomic databases

eggNOGi COG1369.
HOGENOMi HOG000286243.
KOi K03537.
OMAi NPWLIDY.

Enzyme and pathway databases

BioCyci MMAZ192952:GCK2-2679-MONOMER.

Family and domain databases

HAMAPi MF_00755. RNase_P_2.
InterProi IPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view ]
Pfami PF01900. RNase_P_Rpp14. 1 hit.
[Graphical view ]
PIRSFi PIRSF004952. RNase_P_2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea."
    Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R.
    , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Entry informationi

Entry nameiRNP2_METMA
AccessioniPrimary (citable) accession number: Q8PTU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3