Q8PTU2 (RNP2_METMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	MM_2619

Organism

Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) [Complete proteome] [HAMAP]

Taxonomic identifier

192952 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Ribonuclease P protein component 2 HAMAP MF_00755		PRO_0000140022

Sequences

	Sequence		Length	Mass (Da)
	Q8PTU2 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: F4FE4B094476C847	FASTA	116	12,653
	10 20 30 40 50 60 MKRLLPSLRA KKRYLAFELI SEEPASRSDI VKEVMSSASS LLGDVTTSDC DIRVLGFENG 70 80 90 100 110 KGIIQCSHTK VKQTRASLAA LTRINGKRAT LHVLGVSGTV KRATEKFLQD EGVFSS

References

[1]

"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea." Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R. , Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G. J. Mol. Microbiol. Biotechnol. 4:453-461(2002) [PubMed: 12125824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008384 Genomic DNA. Translation: AAM32315.1.
RefSeq	NP_634643.1. NC_003901.1.
3D structure databases
ProteinModelPortal	Q8PTU2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1480961.
GenomeReviews	Gene locus MM_2619 in contig AE008384_GR.
KEGG	mma:MM_2619.
NMPDR	fig|192952.1.peg.2619.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG551631.
OMA	RACEEKY.
ProtClustDB	CLSK2558365.
Enzyme and pathway databases
BioCyc	MMAZ192952:MM2619-MONOMER.
Family and domain databases
HAMAP	MF_00755. RNase_P_2. [Tree]
InterPro	IPR002759. RNase_P/MRP_subunit. IPR016434. RNase_P_comp-2. [Graphical view]
KO	K03537.
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_METMA

Accession

Primary (citable) accession number: Q8PTU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	October 1, 2002
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program